Patents by Inventor Leying Chen

Leying Chen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210322361
    Abstract: The present application relates to use of a nitric oxide releasing agent in the preparation of a medicament for preventing or treating diseases or disorders associated with administration of a VEGFR inhibitor and/or VEGF inhibitor. The present application further provides a method for preventing or treating diseases or disorders associated with administration of a VEGFR inhibitor and/or VEGF inhibitor in a subject. The mothed comprise administering, to a subject in need, a prophylactically or therapeutically effective amount of the nitric oxide releasing agent.
    Type: Application
    Filed: March 29, 2021
    Publication date: October 21, 2021
    Inventors: Shiyi Zhang, Zhaoyu Wu, Chao Liu, Linan Yang, Leying Chen, Jie Luo
  • Patent number: 10987336
    Abstract: The present application relates to use of a nitric oxide releasing agent in the preparation of a medicament for preventing or treating diseases or disorders associated with administration of a VEGFR inhibitor and/or VEGF inhibitor. The present application further provides a method for preventing or treating diseases or disorders associated with administration of a VEGFR inhibitor and/or VEGF inhibitor in a subject. The method comprise administering, to a subject in need, a prophylactically or therapeutically effective amount of the nitric oxide releasing agent.
    Type: Grant
    Filed: April 22, 2020
    Date of Patent: April 27, 2021
    Assignee: ONQUALITY PHARMACEUTICALS CHINA LTD.
    Inventors: Shiyi Zhang, Zhaoyu Wu, Chao Liu, Linan Yang, Leying Chen, Jie Luo
  • Publication number: 20200253915
    Abstract: The present application relates to use of a nitric oxide releasing agent in the preparation of a medicament for preventing or treating diseases or disorders associated with administration of a VEGFR inhibitor and/or VEGF inhibitor. The present application further provides a method for preventing or treating diseases or disorders associated with administration of a VEGFR inhibitor and/or VEGF inhibitor in a subject. The method comprise administering, to a subject in need, a prophylactically or therapeutically effective amount of the nitric oxide releasing agent.
    Type: Application
    Filed: April 22, 2020
    Publication date: August 13, 2020
    Inventors: Shiyi Zhang, Zhaoyu Wu, Chao Liu, Linan Yang, Leying Chen, Jie Luo
  • Patent number: 10583111
    Abstract: The present application provides a use of a nitric oxide releasing agent in preparing a medicament, wherein the medicament is used for preventing or treating EGFR inhibition associated epithelial diseases in a subject. The present application further provides a pharmaceutical composition or a kit comprising EGFR inhibitor and nitric oxide releasing agent.
    Type: Grant
    Filed: May 28, 2019
    Date of Patent: March 10, 2020
    Assignee: ONQUALITY PHARMACEUTICALS CHINA LTD.
    Inventors: Shiyi Zhang, Zhaoyu Wu, Chao Liu, Leying Chen, Xin Zhao, Zhehui Gong, Rui Xing, Songxuan Sun, Jie Luo
  • Publication number: 20190282536
    Abstract: The present application provides a use of a nitric oxide releasing agent in preparing a medicament, wherein the medicament is used for preventing or treating EGFR inhibition associated epithelial diseases in a subject. The present application further provides a pharmaceutical composition or a kit comprising EGFR inhibitor and nitric oxide releasing agent.
    Type: Application
    Filed: May 28, 2019
    Publication date: September 19, 2019
    Inventors: Shiyi Zhang, Zhaoyu Wu, Chao Liu, Leying Chen, Xin Zhao, Zhehui Gong, Rui Xing, Songxuan Sun, Jie Luo