Patents by Inventor Leyuan Xu

Leyuan Xu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions Comprising 5-Cholesten-3, 25-Diol, 3-Sulfate (25HC3S) or Pharmaceutically Acceptable Salt Thereof And at Least One Cyclic Oligosaccharide
    Publication number: 20250249021
    Abstract: Compositions comprising 5-cholesten-3, 25-diol, 3-sulfate (25HC3S) or pharmaceutically acceptable salt thereof and at least one cyclic oligosaccharide, e.g., a cyclodextrin (CD), are provided. The compositions may be used to prevent and/or treat a variety of diseases and conditions, including organ failure (e.g. acute liver failure), high cholesterol/high lipids, and various inflammatory diseases and conditions.
    Type: Application
    Filed: January 6, 2025
    Publication date: August 7, 2025
    Inventors: Shunlin Ren, Leyuan Xu, Yanxia Ning, Jin Koung Kim, WeiQi Lin, Andrew R. Miksztal, Hongwei Wu, Min L. Lee
  • Compositions comprising 5-cholesten-3, 25-diol, 3-sulfate (25HC3S) or pharmaceutically acceptable salt thereof and at least one cyclic oligosaccharide
    Patent number: 12226423
    Abstract: Compositions comprising 5-cholesten-3, 25-diol, 3-sulfate (25HC3S) or pharmaceutically acceptable salt thereof and at least one cyclic oligosaccharide, e.g., a cyclodextrin (CD), are provided. The compositions may be used to prevent and/or treat a variety of diseases and conditions, including organ failure (e.g. acute liver failure), high cholesterol/high lipids, and various inflammatory diseases and conditions.
    Type: Grant
    Filed: June 28, 2022
    Date of Patent: February 18, 2025
    Assignees: Virginia Commonwealth University, Durect Corporation, The United States Government as Represented by The Department of Veterans Affairs
    Inventors: Shunlin Ren, Leyuan Xu, Yanxia Ning, Jin Koung Kim, WeiQi Lin, Andrew R. Miksztal, Hongwei Wu, Min L. Lee
  • COMPOSITIONS COMPRISING 5-CHOLESTEN-3, 25-DIOL, 3-SULFATE (25HC3S) OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF AND AT LEAST ONE CYCLIC OLIGOSACCHARIDE
    Publication number: 20230047788
    Abstract: Compositions comprising 5-cholesten-3, 25-diol, 3-sulfate (25HC3S) or pharmaceutically acceptable salt thereof and at least one cyclic oligosaccharide, e.g., a cyclodextrin (CD), are provided. The compositions may be used to prevent and/or treat a variety of diseases and conditions, including organ failure (e.g. acute liver failure), high cholesterol/high lipids, and various inflammatory diseases and conditions.
    Type: Application
    Filed: June 28, 2022
    Publication date: February 16, 2023
    Inventors: Shunlin Ren, Leyuan Xu, Yanxia Ning, Jin Koung Kim, WeiQi Lin, Andrew R. Miksztal, Hongwei Wu, Min L. Lee
  • Compositions comprising 5-cholesten-3, 25-diol, 3-sulfate (25HC3S) or pharmaceutically acceptable salt thereof and at least one cyclic oligosaccharide
    Patent number: 11406646
    Abstract: Compositions comprising 5-cholesten-3,25-diol, 3-sulfate (25HC3S) or pharmaceutically acceptable salt thereof and at least one cyclic oligosaccharide, e.g., a cyclodextrin (CD), are provided. The compositions may be used to prevent and/or treat a variety of diseases and conditions, including organ failure (e.g. acute liver failure), high cholesterol/high lipids, and various inflammatory diseases and conditions.
    Type: Grant
    Filed: November 10, 2020
    Date of Patent: August 9, 2022
    Assignees: Virginia Commonwealth University, Durect Corporation, The United States Government as Represented by The Department of Veterans Affairs
    Inventors: Shunlin Ren, Leyuan Xu, Yanxia Ning, Jin Koung Kim, WeiQi Lin, Andrew R. Miksztal, Hongwei Wu, Min L. Lee
  • COMPOSITIONS COMPRISING 5-CHOLESTEN-3, 25-DIOL, 3-SULFATE (25HC3S) OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF AND AT LEAST ONE CYCLIC OLIGOSACCHARIDE
    Publication number: 20210169898
    Abstract: Compositions comprising 5-cholesten-3, 25-diol, 3-sulfate (25HC3S) or pharmaceutically acceptable salt thereof and at least one cyclic oligosaccharide, e.g., a cyclodextrin (CD), are provided. The compositions may be used to prevent and/or treat a variety of diseases and conditions, including organ failure (e.g. acute liver failure), high cholesterol/high lipids, and various inflammatory diseases and conditions.
    Type: Application
    Filed: November 10, 2020
    Publication date: June 10, 2021
    Inventors: Shunlin Ren, Leyuan Xu, Yanxia Ning, Jin Koung Kim, WeiQi Lin, Mee Jean Kim, Andrew R. Miksztal, Hongwei Wu, Min L. Lee, Wilma Tamraz
  • Service Data Transmission Method, Network Device, and Terminal Device
    Publication number: 20190320297
    Abstract: This application provides a service data transmission method, a network device, and a terminal device. A network device sends a first indication message to a terminal device, where the first indication message indicates a second air interface parameter configuration, and the first indication message is sent by using an air interface resource with a first air interface parameter configuration. The network device performs service data transmission with the terminal device by using an air interface resource with the second air interface parameter configuration.
    Type: Application
    Filed: June 28, 2019
    Publication date: October 17, 2019
    Inventors: Leyuan Xu, Shaofeng Sun
  • COMPOSITIONS COMPRISING 5-CHOLESTEN-3, 25-DIOL, 3-SULFATE (25HC3S) OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF AND AT LEAST ONE CYCLIC OLIGOSACCHARIDE
    Publication number: 20190269695
    Abstract: Compositions comprising 5-cholesten-3, 25-diol, 3-sulfate (25HC3S) or pharmaceutically acceptable salt thereof and at least one cyclic oligosaccharide, e.g., a cyclodextrin (CD), are provided. The compositions may be used to prevent and/or treat a variety of diseases and conditions, including organ failure (e.g. acute liver failure), high cholesterol/high lipids, and various inflammatory diseases and conditions.
    Type: Application
    Filed: August 1, 2017
    Publication date: September 5, 2019
    Inventors: Shunlin Ren, Leyuan Xu, Yanxia Ning, Jin Koung Kim, WeiQi Lin, Mee Jean Kim, Andrew R. Miksztal, Hongwei Wu, Min L. Lee, Wilma Tamraz