Patents by Inventor Lgnace Laster

Lgnace Laster has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Antibody variants having modifications in the constant region
    Patent number: 9085625
    Abstract: The present invention relates to positions in the constant region of antibodies, in particular the CH3 region of IgG4, which affect the strength of CH3-CH3 interactions. Mutations that either stabilize or destabilize this interaction are disclosed.
    Type: Grant
    Filed: December 3, 2009
    Date of Patent: July 21, 2015
    Assignee: Genmab A/S
    Inventors: Aran Frank Labrijn, Stefan Loverix, Paul Parren, Jau Van De Winkel, Janine Schuurman, Lgnace Laster
  • Antibody Variants Having Modifications In The Constant Region
    Publication number: 20110293607
    Abstract: The present invention relates to positions in the constant region of antibodies, in particular the CH3 region of IgG4, which affect the strength of CH3-CH3 interactions. Mutations that either stabilize or destabilize this interaction are disclosed.
    Type: Application
    Filed: December 3, 2009
    Publication date: December 1, 2011
    Inventors: Aran Frank Labrijn, Stefan Loverix, Paul Parren, Jau Van De Winkel, Janine Schuurman, Lgnace Laster