Abstract: A tape for detecting bio-analytes is provided. The tape includes a flexible, elongate band defining identifiable sections disposed lengthwise thereon. The tape also includes biological or biochemical probes. At least one probe is attached to a section. Probes in different sections are capable of binding specifically to different biological or biochemical targets. The tape can be enclosed in a cassette. Sections of the tape can be advanced sequentially to a test location. Whether a probe in a section has bonded to a corresponding target is detected when the section is at the test location. A detection system for use with the tape or cassette can include a mechanism for holding the tape and advancing the tape lengthwise through a detection location, and a detector disposed proximate the detection location, for detecting a signal originated from a section of the tape at the detection location.