Abstract: In some embodiments, the present disclosure relates to a method for manufacturing an integrated chip. The method includes forming a transistor structure over a substrate. The transistor structure comprises a pair of source/drain regions and a gate electrode between the source/drain regions. A lower inter-level dielectric (ILD) layer is formed over the pair of source/drain regions and around the gate electrode. A gate capping layer is formed over the gate electrode. A selective etch and deposition process is performed to form a dielectric protection layer on the gate capping layer while forming a contact opening within the lower ILD layer. A lower source/drain contact is formed within the contact opening.

Abstract: In one aspect, a system for in vivo and transcranial stimulation of brain tissue of a subject may include at least one light source, a controller to control operation of the light source, a signal detecting unit and a processor configured to receive signals from the signal detecting unit, analyze the signals and generate a feedback signal to the controller to control the light source until optimal results are obtained. In one embodiment, the light source is a laser instrument and the wavelength can range from 800 to 1100 nm. In another embodiment, the irradiance of the laser instrument can range from 50 to 1000 mW/cm2.

Abstract: An orthopedic insole may include at least one strength layer and at least one shock absorbing layer. In one embodiment, the strength layer may be relatively rigid and includes a heel portion and an arch portion, contoured to fit the plantar or bottom surface of the foot to provide arch support. The shock absorbing layer may include a plurality of shock absorbing cells such as recoverable honeycombs or any other negative stiffness structure with the capability to recover. A gait analysis that may include an individual's weight transfer trajectory may have to be conducted to determine the structure of the shock absorbing layer. The orthopedic insole may further include an adjusting layer to supplement the strength layer and the shock absorbing layer to make adjustment to the orthopedic insole if needed.

Abstract: In one aspect, a system for in vivo and transcranial stimulation of brain tissue of a subject may include at least one light source, a controller to control operation of the light source, a signal detecting unit and a processor configured to receive signals from the signal detecting unit, analyze the signals and generate a feedback signal to the controller to control the light source until optimal results are obtained. In one embodiment, the light source is a laser instrument and the wavelength can range from 800 to 1100 nm. In another embodiment, the irradiance of the laser instrument can range from 50 to 1000 mW/cm2.

Abstract: In one aspect, a system for in vivo stimulation of targeted tissues of a subject integrated in Exosome and/or stem cell therapies may include at least one light source, a controller to control operation of the light source, a signal detecting unit and a processor configured to receive signals from the signal detecting unit, analyze the signals and generate a feedback signal to the controller to control the light source until optimal results are obtained. In one embodiment, the light source is a laser instrument and the wavelength can range from 400 to 1100 nm. In another embodiment, the irradiance of the laser instrument can range from 10 to 3000 mW/cm2.

Abstract: In one aspect, a system for in vivo and transcranial stimulation of brain tissue of a subject may include at least one light source, a controller to control operation of the light source, a signal detecting unit and a processor configured to receive signals from the signal detecting unit, analyze the signals and generate a feedback signal to the controller to control the light source until optimal results are obtained. In one embodiment, the light source is a laser instrument and the wavelength can range from 800 to 1100 nm. In another embodiment, the irradiance of the laser instrument can range from 50 to 1000 mW/cm2.

Abstract: In one aspect, a method for measuring cell metabolism through photobiomodulation comprising steps of receiving a broadband near-infrared spectroscopy (bbNIRS) image including one or more responding signals to light stimulation regarding a specific cell; extracting two or more turning points on one of the responding signals; extracting two or more threshold points on one of the responding signals; generating a first line by curve fitting to approximate the turning points on the responding signal and determining a slop of the first line; generating a second line by curve fitting to approximate the threshold points on the responding signal and determining a slop of the second line; and comparing the input images, the first line and the second line to determine a rate of cell metabolism of the specific cell.

Abstract: A system for in vivo and transcranial stimulation of brain tissue of a subject may include at least one light source; a controller to control operation of the light source; a signal detecting unit and a processor configured to receive a signal from the signal detecting unit; analyze the signal and generate a feedback signal to the controller to control the light source until optimal results are obtained, wherein the detected signal is an electroencephalogram (EEG) signal, on which local peak frequencies are extracted and recorded periodically and repeatedly within a predetermined time frame before, during and after light stimulation, and the feedback signal is generated by comparing the local peak frequencies of before, during and after the brain stimulation to determine if brain synchronization occurs and sustains, and the feedback signal is generated.

Abstract: In one aspect, a system for in vivo and transcranial stimulation of brain tissue of a subject may include at least one light source, a controller to control operation of the light source, a signal detecting unit and a processor configured to receive signals from the signal detecting unit, analyze the signals and generate a feedback signal to the controller to control the light source until optimal results are obtained. In one embodiment, the light source is a laser instrument and the wavelength can range from 800 to 1100 nm. In another embodiment, the irradiance of the laser instrument can range from 50 to 1000 mW/cm2.

Abstract: A manufacturing method of a semiconductor device including the following steps is provided. A substrate having a device structure and a first interconnection structure on a front side is provided. A first annealing process is performed in an atmosphere of pure hydrogen at a first temperature. A second interconnection structure is formed on a back side of the substrate. A second annealing process is performed in an atmosphere of gas mixture including hydrogen at a second temperature.

Abstract: A manufacturing method of a semiconductor device including the following steps is provided. A substrate having a device structure and a first interconnection structure on a front side is provided. A first annealing process is performed in an atmosphere of pure hydrogen at a first temperature. A second interconnection structure is formed on a back side of the substrate. A second annealing process is performed in an atmosphere of gas mixture including hydrogen at a second temperature.

Abstract: In one aspect, a system for in vivo and transcranial stimulation of brain tissue of a subject may include at least one light source, a controller to control operation of the light source, a signal detecting unit and a processor configured to receive signals from the signal detecting unit, analyze the signals and generate a feedback signal to the controller to control the light source until optimal results are obtained. In one embodiment, the light source is a laser instrument and the wavelength can range from 800 to 1100 nm. In another embodiment, the irradiance of the laser instrument can range from 50 to 1000 mW/cm2.

Abstract: A system to generate and control a three-dimensional (3D) surface may include a surface supported by a plurality of actuating units, a control center, and a common media tank. The control center may include a movement control assembly that has a plurality of movement control unit, and each movement control unit is configured to control the movement of a corresponding actuating unit. In one embodiment, a predetermined amount of medium, such as air or liquid, is arranged in each actuating unit. The surface can be actually considered an array of small pieces divided from the surface, and supported and actuated by the actuating units. Since the control of the surface is through the control of every single piece thereof, the control of the surface would be more precise if the surface can be divided into more pieces.

Abstract: An orthopedic insole may include at least one strength layer and at least one shock absorbing layer. In one embodiment, the strength layer may be relatively rigid and includes a heel portion and an arch portion, contoured to fit the plantar or bottom surface of the foot to provide arch support. The shock absorbing layer may include a plurality of shock absorbing cells such as recoverable honeycombs or any other negative stiffness structure with the capability to recover. A gait analysis that may include an individual's weight transfer trajectory may have to be conducted to determine the structure of the shock absorbing layer. The orthopedic insole may further include an adjusting layer to supplement the strength layer and the shock absorbing layer to make adjustment to the orthopedic insole if needed.

Abstract: A system to generate and control a three-dimensional (3D) surface may include a surface supported by a plurality of actuating units, a control center, and a common media tank. The control center may include a movement control assembly that has a plurality of movement control unit, and each movement control unit is configured to control the movement of a corresponding actuating unit. In one embodiment, a predetermined amount of medium, such as air or liquid, is arranged in each actuating unit. The surface can be actually considered an array of small pieces divided from the surface, and supported and actuated by the actuating units. Since the control of the surface is through the control of every single piece thereof, the control of the surface would be more precise if the surface can be divided into more pieces.

Abstract: The invention provides a collaboration method for spatial navigation, including the steps of: providing a plurality of entities; building a self map; constructing a virtual self map, wherein the self map and at least one cognitive map received form at least one other entity are overlapped by combining at least one first possible match portion between the self map and at least one cognitive map when a confidence index of the cognitive map is no less than a threshold value; and constructing a virtual whole map, by repeating the step of constructing the virtual self map to form the virtual whole map for a specific space. Therefore, using the collaboration method for spatial navigation, the virtual whole map can be constructed in a short time, and the optimal virtual whole map can be obtained to improve the precision of the virtual whole map.