Patents by Inventor Li-Hsin LIN
Li-Hsin LIN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Publication number: 20250129316Abstract: This disclosure relates to a biological tissue forming method includes the following steps: providing a biological tissue forming package with a base, a membrane, a sliding assembly and a sealing film that seals a chamber of the base used for receiving the membrane and the sliding assembly with one of the base and the sealing film being light-transmitting; passing a biological tissue fluid through the sealing film and the sliding assembly so as to be dispensed on the membrane; moving the sliding assembly away from a covering position used for covering the membrane via at least one passive magnetic element so as to expose the biological tissue fluid on the membrane; and emitting the biological tissue fluid exposed on the membrane by a curing light transmitting through the one of the base and the sealing film so as to cure the biological tissue fluid into a biological tissue.Type: ApplicationFiled: December 15, 2023Publication date: April 24, 2025Applicant: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTEInventors: Chao-Hong HSU, Teng-Yen WANG, Yang-Cheng LIN, Hsin-Yi HSU, Yu-Bing LIOU, Chang-Chou LI, Chih-Hung HUANG, Tung-Ying LIN, Li-Hsin LIN, Yuchi WANG, Hsin-Hsin SHEN
-
Patent number: 12258546Abstract: A cell and tissue sheet forming package includes a container body, a membrane, a sliding door plate and a sealing film. The sliding door plate is disposed slidably on a top of the container body to cover or expose the membrane. The sliding door plate has a hole and a passive magnetic assembly. The cell injection equipment includes a carrier, an injection mechanism and a drive mechanism. The carrier carries the package, and the drive mechanism moves the carrier and the injection mechanism to have the injection mechanism to inject a solution, through the hole, into the package. A heating element of the carrier is introduced to heat the membrane and the solution to transform the solution into a colloid sheet on the membrane. Then, the positive magnetic assembly engages magnetically the passive magnetic assembly to slide the sliding door plate to expose the colloid sheet on the membrane.Type: GrantFiled: December 23, 2021Date of Patent: March 25, 2025Assignee: Industrial Technology Research InstituteInventors: Hsin-Yi Hsu, Yang-Cheng Lin, Chao-Hong Hsu, Yu-Bing Liou, Li-Hsin Lin, Hsin-Hsin Shen, Yu-Chi Wang, Chang-Chou Li, Chih-Hung Huang
-
Patent number: 12227759Abstract: A temperature-sensitive cell culture composition is provided. The temperature-sensitive cell culture composition includes a hydrogel, a cellulose, a gelatin and a collagen. Based on 1 part by weight of the collagen, a content of the hydrogel is between 0.03 parts by weight and 60 parts by weight, a content of the cellulose is between 150 parts by weight and 360 parts by weight, and a content of the gelatin is between 21 parts by weight and 12 parts by weight. In addition, a method for using the temperature-sensitive cell culture composition, a method for forming the temperature-sensitive cell culture composition, and a use of the temperature-sensitive cell culture composition are also provided.Type: GrantFiled: December 18, 2020Date of Patent: February 18, 2025Assignee: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTEInventors: Chia-Jung Lu, Jing-En Huang, Liang-Cheng Su, Hsin-Hsin Shen, Yuchi Wang, Ying-Hsueh Chao, Li-Hsin Lin, Hsiu-Hua Huang
-
Patent number: 12054612Abstract: A bioprintable material is provided. The bioprintable material includes a hydrogel and microfilaments mixed in the hydrogel. The hydrogel includes a first collagen. The microfilament includes a second collagen. The diameter of the microfilament is ranging from 5 microns to 200 microns. The weight ratio of the microfilaments to the first collagen is ranging from 0.01:1 to 10:1.Type: GrantFiled: December 23, 2021Date of Patent: August 6, 2024Assignee: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTEInventors: Yun-Chung Teng, Jen-Huang Huang, Ying-Wen Shen, Yu-Bing Liou, Hsin-Yi Hsu, Li-Hsin Lin, Yuchi Wang, Hsin-Hsin Shen
-
Patent number: 11760853Abstract: An anti-curling film is provided. The anti-curling film includes a first portion and a second portion covering the first portion. The first portion includes polylactic acid (PLA), polycaprolactone (PCL), polyethylene glycol dimethacrylate (PEGDMA) and a photoinitiator. The second portion includes polycaprolactone (PCL), gelatin, hyaluronic acid (HA), alginate (AA), polyvinyl alcohol (PVA) or a combination thereof.Type: GrantFiled: November 30, 2021Date of Patent: September 19, 2023Assignee: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTEInventors: Wei-Hong Chang, Ching-Mei Chen, Grace H. Chen, Hsin-Hsin Shen, Yuchi Wang, Ming-Chia Yang, Li-Hsin Lin, Sen-Lu Chen, Yi-Hsuan Lee, Jian-Wei Lin, Liang-Cheng Su
-
Publication number: 20230203415Abstract: A cell and tissue sheet forming package includes a container body, a membrane, a sliding door plate and a sealing film. The sliding door plate is disposed slidably on a top of the container body to cover or expose the membrane. The sliding door plate has a hole and a passive magnetic assembly. The cell injection equipment includes a carrier, an injection mechanism and a drive mechanism. The carrier carries the package, and the drive mechanism moves the carrier and the injection mechanism to have the injection mechanism to inject a solution, through the hole, into the package. A heating element of the carrier is introduced to heat the membrane and the solution to transform the solution into a colloid sheet on the membrane. Then, the positive magnetic assembly engages magnetically the passive magnetic assembly to slide the sliding door plate to expose the colloid sheet on the membrane.Type: ApplicationFiled: December 23, 2021Publication date: June 29, 2023Inventors: HSIN-YI HSU, YANG-CHENG LIN, CHAO-HONG HSU, YU-BING LIOU, LI-HSIN LIN, HSIN-HSIN SHEN, YU-CHI WANG, CHANG-CHOU LI, CHIH-HUNG HUANG
-
Publication number: 20220204772Abstract: A bioprintable material is provided. The bioprintable material includes a hydrogel and microfilaments mixed in the hydrogel. The hydrogel includes a first collagen. The microfilament includes a second collagen. The diameter of the microfilament is ranging from 5 microns to 200 microns. The weight ratio of the microfilaments to the first collagen is ranging from 0.01:1 to 10:1.Type: ApplicationFiled: December 23, 2021Publication date: June 30, 2022Applicant: Industrial Technology Research InstituteInventors: Yun-Chung TENG, Jen-Huang HUANG, Ying-Wen SHEN, Yu-Bing LIOU, Hsin-Yi HSU, Li-Hsin LIN, Yuchi WANG, Hsin-Hsin SHEN
-
Publication number: 20220169808Abstract: An anti-curling film is provided. The anti-curling film includes a first portion and a second portion covering the first portion. The first portion includes polylactic acid (PLA), polycaprolactone (PCL), polyethylene glycol dimethacrylate (PEGDMA) and a photoinitiator. The second portion includes polycaprolactone (PCL), gelatin, hyaluronic acid (HA), alginate (AA), polyvinyl alcohol (PVA) or a combination thereof.Type: ApplicationFiled: November 30, 2021Publication date: June 2, 2022Applicant: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTEInventors: Wei-Hong CHANG, Ching-Mei CHEN, Grace H. CHEN, Hsin-Hsin SHEN, Yuchi WANG, Ming-Chia YANG, Li-Hsin LIN, Sen-Lu CHEN, Yi-Hsuan LEE, Jian-Wei LIN, Liang-Cheng SU
-
Publication number: 20210269765Abstract: A temperature-sensitive cell culture composition is provided. The temperature-sensitive cell culture composition includes a hydrogel, a cellulose, a gelatin and a collagen. Based on 1 part by weight of the collagen, a content of the hydrogel is between 0.03 parts by weight and 60 parts by weight, a content of the cellulose is between 150 parts by weight and 360 parts by weight, and a content of the gelatin is between 21 parts by weight and 12 parts by weight. In addition, a method for using the temperature-sensitive cell culture composition, a method for forming the temperature-sensitive cell culture composition, and a use of the temperature-sensitive cell culture composition are also provided.Type: ApplicationFiled: December 18, 2020Publication date: September 2, 2021Applicant: Industrial Technology Research InstituteInventors: Chia-Jung LU, Jing-En HUANG, Liang-Cheng SU, Hsin-Hsin SHEN, Yuchi WANG, Ying-Hsueh CHAO, Li-Hsin LIN, Hsiu-Hua HUANG
-
Publication number: 20210196648Abstract: A drug-containing multilayer film provided. The drug-containing multilayer film includes: a drug-containing layer; and an anti-adhesion layer on a surface of the drug-containing layer. The drug-containing layer is composed of a first composition including a first polymer material and a drug, and the first polymer material includes at least one selected from the group consisting of: polylactic acid (PLA) and polyethylene glycol (PEG), and the weight ratio of the first polymer material to the drug is about 1:0.01-0.3. The anti-adhesion layer is composed of a second composition, and the second composition includes a second polymer material, and the second polymer material includes at least one selected from the group consisting of polylactic acid and polyethylene glycol.Type: ApplicationFiled: December 31, 2019Publication date: July 1, 2021Applicant: Industrial Technology Research InstituteInventors: Hsin-Hsin SHEN, Yuchi WANG, Li-Hsin LIN, Ming-Chia YANG, Hsiu-Hua HUANG, Liang-Cheng SU, Ying-Hsueh CHAO, Jing-En HUANG
-
Patent number: 9107979Abstract: A bioresorbable porous film, including a blend mixture of polylactic acid and at least two kinds of polyethylene glycol, wherein the at least two kinds of polyethylene glycol include a first polyethylene glycol, which is in a solid form under ambient temperature and atmospheric pressure, and a second polyethylene glycol, which is in a liquid form under ambient temperature and atmospheric pressure is provided. The film has a porosity of 10%-90%.Type: GrantFiled: April 25, 2013Date of Patent: August 18, 2015Assignee: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTEInventors: Li-Hsin Lin, Hsin-Hsin Shen, Ying-Hsueh Chao, Hsiu-Hua Huang, Yu-Bing Liou, Chih-Bing Hung, Chin-Fu Chen
-
Patent number: 9084822Abstract: The disclosure provides a solid form and a method for preparing the same. The solid form consists essentially of a biodegradable copolymer and an amide-containing compound. The biodegradable copolymer is semi-crystalline due to the dipole-dipole interaction between the biodegradable copolymer and the urea. The method for preparing the above solid form includes: dissolving a biodegradable copolymer and an amide-containing compound in water at a first temperature, obtaining a solution; cooling the solution at a second temperature to form a solid mixture; and the solid mixture is subjected to a freeze-drying process at a third temperature.Type: GrantFiled: April 26, 2013Date of Patent: July 21, 2015Assignee: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTEInventors: Hsin-Hsin Shen, Yu-Bing Liou, Chin-Fu Chen, Li-Hsin Lin, Hsiu-Hua Huang, Ying-Hsueh Chao, Meng-Yow Hsieh, Miao-Tzu Chen, Chih-Bing Hung
-
Publication number: 20140187591Abstract: The disclosure provides a solid form and a method for preparing the same. The solid form consists essentially of a biodegradable copolymer and an amide-containing compound. The biodegradable copolymer is semi-crystalline due to the dipole-dipole interaction between the biodegradable copolymer and the urea. The method for preparing the above solid form includes: dissolving a biodegradable copolymer and an amide-containing compound in water at a first temperature, obtaining a solution; cooling the solution at a second temperature to form a solid mixture; and the solid mixture is subjected to a freeze-drying process at a third temperature.Type: ApplicationFiled: April 26, 2013Publication date: July 3, 2014Applicant: Industrial Technology Research InstituteInventors: Hsin-Hsin SHEN, Yu-Bing LIOU, Chin-Fu CHEN, Li-Hsin LIN, Hsiu-Hua HUANG, Ying-Hsueh CHAO, Meng-Yow HSIEH, Miao-Tzu CHEN, Chih-Bing HUNG
-
Publication number: 20140161842Abstract: A bioresorbable porous film, including a blend mixture of polylactic acid and at least two kinds of polyethylene glycol, wherein the at least two kinds of polyethylene glycol include a first polyethylene glycol, which is in a solid form under ambient temperature and atmospheric pressure, and a second polyethylene glycol, which is in a liquid form under ambient temperature and atmospheric pressure is provided. The film has a porosity of 10%-90%.Type: ApplicationFiled: April 25, 2013Publication date: June 12, 2014Applicant: Industrial Technology Research InstituteInventors: Li-Hsin LIN, Hsin-Hsin SHEN, Ying-Hsueh CHAO, Hsiu-Hua HUANG, Yu-Bing LIOU, Chih-Bing HUNG, Chin-Fu CHEN