Patents by Inventor Li-Hsin LIN

Li-Hsin LIN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20250129316
    Abstract: This disclosure relates to a biological tissue forming method includes the following steps: providing a biological tissue forming package with a base, a membrane, a sliding assembly and a sealing film that seals a chamber of the base used for receiving the membrane and the sliding assembly with one of the base and the sealing film being light-transmitting; passing a biological tissue fluid through the sealing film and the sliding assembly so as to be dispensed on the membrane; moving the sliding assembly away from a covering position used for covering the membrane via at least one passive magnetic element so as to expose the biological tissue fluid on the membrane; and emitting the biological tissue fluid exposed on the membrane by a curing light transmitting through the one of the base and the sealing film so as to cure the biological tissue fluid into a biological tissue.
    Type: Application
    Filed: December 15, 2023
    Publication date: April 24, 2025
    Applicant: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
    Inventors: Chao-Hong HSU, Teng-Yen WANG, Yang-Cheng LIN, Hsin-Yi HSU, Yu-Bing LIOU, Chang-Chou LI, Chih-Hung HUANG, Tung-Ying LIN, Li-Hsin LIN, Yuchi WANG, Hsin-Hsin SHEN
  • Patent number: 12258546
    Abstract: A cell and tissue sheet forming package includes a container body, a membrane, a sliding door plate and a sealing film. The sliding door plate is disposed slidably on a top of the container body to cover or expose the membrane. The sliding door plate has a hole and a passive magnetic assembly. The cell injection equipment includes a carrier, an injection mechanism and a drive mechanism. The carrier carries the package, and the drive mechanism moves the carrier and the injection mechanism to have the injection mechanism to inject a solution, through the hole, into the package. A heating element of the carrier is introduced to heat the membrane and the solution to transform the solution into a colloid sheet on the membrane. Then, the positive magnetic assembly engages magnetically the passive magnetic assembly to slide the sliding door plate to expose the colloid sheet on the membrane.
    Type: Grant
    Filed: December 23, 2021
    Date of Patent: March 25, 2025
    Assignee: Industrial Technology Research Institute
    Inventors: Hsin-Yi Hsu, Yang-Cheng Lin, Chao-Hong Hsu, Yu-Bing Liou, Li-Hsin Lin, Hsin-Hsin Shen, Yu-Chi Wang, Chang-Chou Li, Chih-Hung Huang
  • Patent number: 12227759
    Abstract: A temperature-sensitive cell culture composition is provided. The temperature-sensitive cell culture composition includes a hydrogel, a cellulose, a gelatin and a collagen. Based on 1 part by weight of the collagen, a content of the hydrogel is between 0.03 parts by weight and 60 parts by weight, a content of the cellulose is between 150 parts by weight and 360 parts by weight, and a content of the gelatin is between 21 parts by weight and 12 parts by weight. In addition, a method for using the temperature-sensitive cell culture composition, a method for forming the temperature-sensitive cell culture composition, and a use of the temperature-sensitive cell culture composition are also provided.
    Type: Grant
    Filed: December 18, 2020
    Date of Patent: February 18, 2025
    Assignee: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
    Inventors: Chia-Jung Lu, Jing-En Huang, Liang-Cheng Su, Hsin-Hsin Shen, Yuchi Wang, Ying-Hsueh Chao, Li-Hsin Lin, Hsiu-Hua Huang
  • Patent number: 12054612
    Abstract: A bioprintable material is provided. The bioprintable material includes a hydrogel and microfilaments mixed in the hydrogel. The hydrogel includes a first collagen. The microfilament includes a second collagen. The diameter of the microfilament is ranging from 5 microns to 200 microns. The weight ratio of the microfilaments to the first collagen is ranging from 0.01:1 to 10:1.
    Type: Grant
    Filed: December 23, 2021
    Date of Patent: August 6, 2024
    Assignee: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
    Inventors: Yun-Chung Teng, Jen-Huang Huang, Ying-Wen Shen, Yu-Bing Liou, Hsin-Yi Hsu, Li-Hsin Lin, Yuchi Wang, Hsin-Hsin Shen
  • Patent number: 11760853
    Abstract: An anti-curling film is provided. The anti-curling film includes a first portion and a second portion covering the first portion. The first portion includes polylactic acid (PLA), polycaprolactone (PCL), polyethylene glycol dimethacrylate (PEGDMA) and a photoinitiator. The second portion includes polycaprolactone (PCL), gelatin, hyaluronic acid (HA), alginate (AA), polyvinyl alcohol (PVA) or a combination thereof.
    Type: Grant
    Filed: November 30, 2021
    Date of Patent: September 19, 2023
    Assignee: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
    Inventors: Wei-Hong Chang, Ching-Mei Chen, Grace H. Chen, Hsin-Hsin Shen, Yuchi Wang, Ming-Chia Yang, Li-Hsin Lin, Sen-Lu Chen, Yi-Hsuan Lee, Jian-Wei Lin, Liang-Cheng Su
  • Publication number: 20230203415
    Abstract: A cell and tissue sheet forming package includes a container body, a membrane, a sliding door plate and a sealing film. The sliding door plate is disposed slidably on a top of the container body to cover or expose the membrane. The sliding door plate has a hole and a passive magnetic assembly. The cell injection equipment includes a carrier, an injection mechanism and a drive mechanism. The carrier carries the package, and the drive mechanism moves the carrier and the injection mechanism to have the injection mechanism to inject a solution, through the hole, into the package. A heating element of the carrier is introduced to heat the membrane and the solution to transform the solution into a colloid sheet on the membrane. Then, the positive magnetic assembly engages magnetically the passive magnetic assembly to slide the sliding door plate to expose the colloid sheet on the membrane.
    Type: Application
    Filed: December 23, 2021
    Publication date: June 29, 2023
    Inventors: HSIN-YI HSU, YANG-CHENG LIN, CHAO-HONG HSU, YU-BING LIOU, LI-HSIN LIN, HSIN-HSIN SHEN, YU-CHI WANG, CHANG-CHOU LI, CHIH-HUNG HUANG
  • Publication number: 20220204772
    Abstract: A bioprintable material is provided. The bioprintable material includes a hydrogel and microfilaments mixed in the hydrogel. The hydrogel includes a first collagen. The microfilament includes a second collagen. The diameter of the microfilament is ranging from 5 microns to 200 microns. The weight ratio of the microfilaments to the first collagen is ranging from 0.01:1 to 10:1.
    Type: Application
    Filed: December 23, 2021
    Publication date: June 30, 2022
    Applicant: Industrial Technology Research Institute
    Inventors: Yun-Chung TENG, Jen-Huang HUANG, Ying-Wen SHEN, Yu-Bing LIOU, Hsin-Yi HSU, Li-Hsin LIN, Yuchi WANG, Hsin-Hsin SHEN
  • Publication number: 20220169808
    Abstract: An anti-curling film is provided. The anti-curling film includes a first portion and a second portion covering the first portion. The first portion includes polylactic acid (PLA), polycaprolactone (PCL), polyethylene glycol dimethacrylate (PEGDMA) and a photoinitiator. The second portion includes polycaprolactone (PCL), gelatin, hyaluronic acid (HA), alginate (AA), polyvinyl alcohol (PVA) or a combination thereof.
    Type: Application
    Filed: November 30, 2021
    Publication date: June 2, 2022
    Applicant: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
    Inventors: Wei-Hong CHANG, Ching-Mei CHEN, Grace H. CHEN, Hsin-Hsin SHEN, Yuchi WANG, Ming-Chia YANG, Li-Hsin LIN, Sen-Lu CHEN, Yi-Hsuan LEE, Jian-Wei LIN, Liang-Cheng SU
  • Publication number: 20210269765
    Abstract: A temperature-sensitive cell culture composition is provided. The temperature-sensitive cell culture composition includes a hydrogel, a cellulose, a gelatin and a collagen. Based on 1 part by weight of the collagen, a content of the hydrogel is between 0.03 parts by weight and 60 parts by weight, a content of the cellulose is between 150 parts by weight and 360 parts by weight, and a content of the gelatin is between 21 parts by weight and 12 parts by weight. In addition, a method for using the temperature-sensitive cell culture composition, a method for forming the temperature-sensitive cell culture composition, and a use of the temperature-sensitive cell culture composition are also provided.
    Type: Application
    Filed: December 18, 2020
    Publication date: September 2, 2021
    Applicant: Industrial Technology Research Institute
    Inventors: Chia-Jung LU, Jing-En HUANG, Liang-Cheng SU, Hsin-Hsin SHEN, Yuchi WANG, Ying-Hsueh CHAO, Li-Hsin LIN, Hsiu-Hua HUANG
  • Publication number: 20210196648
    Abstract: A drug-containing multilayer film provided. The drug-containing multilayer film includes: a drug-containing layer; and an anti-adhesion layer on a surface of the drug-containing layer. The drug-containing layer is composed of a first composition including a first polymer material and a drug, and the first polymer material includes at least one selected from the group consisting of: polylactic acid (PLA) and polyethylene glycol (PEG), and the weight ratio of the first polymer material to the drug is about 1:0.01-0.3. The anti-adhesion layer is composed of a second composition, and the second composition includes a second polymer material, and the second polymer material includes at least one selected from the group consisting of polylactic acid and polyethylene glycol.
    Type: Application
    Filed: December 31, 2019
    Publication date: July 1, 2021
    Applicant: Industrial Technology Research Institute
    Inventors: Hsin-Hsin SHEN, Yuchi WANG, Li-Hsin LIN, Ming-Chia YANG, Hsiu-Hua HUANG, Liang-Cheng SU, Ying-Hsueh CHAO, Jing-En HUANG
  • Patent number: 9107979
    Abstract: A bioresorbable porous film, including a blend mixture of polylactic acid and at least two kinds of polyethylene glycol, wherein the at least two kinds of polyethylene glycol include a first polyethylene glycol, which is in a solid form under ambient temperature and atmospheric pressure, and a second polyethylene glycol, which is in a liquid form under ambient temperature and atmospheric pressure is provided. The film has a porosity of 10%-90%.
    Type: Grant
    Filed: April 25, 2013
    Date of Patent: August 18, 2015
    Assignee: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
    Inventors: Li-Hsin Lin, Hsin-Hsin Shen, Ying-Hsueh Chao, Hsiu-Hua Huang, Yu-Bing Liou, Chih-Bing Hung, Chin-Fu Chen
  • Patent number: 9084822
    Abstract: The disclosure provides a solid form and a method for preparing the same. The solid form consists essentially of a biodegradable copolymer and an amide-containing compound. The biodegradable copolymer is semi-crystalline due to the dipole-dipole interaction between the biodegradable copolymer and the urea. The method for preparing the above solid form includes: dissolving a biodegradable copolymer and an amide-containing compound in water at a first temperature, obtaining a solution; cooling the solution at a second temperature to form a solid mixture; and the solid mixture is subjected to a freeze-drying process at a third temperature.
    Type: Grant
    Filed: April 26, 2013
    Date of Patent: July 21, 2015
    Assignee: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
    Inventors: Hsin-Hsin Shen, Yu-Bing Liou, Chin-Fu Chen, Li-Hsin Lin, Hsiu-Hua Huang, Ying-Hsueh Chao, Meng-Yow Hsieh, Miao-Tzu Chen, Chih-Bing Hung
  • Publication number: 20140187591
    Abstract: The disclosure provides a solid form and a method for preparing the same. The solid form consists essentially of a biodegradable copolymer and an amide-containing compound. The biodegradable copolymer is semi-crystalline due to the dipole-dipole interaction between the biodegradable copolymer and the urea. The method for preparing the above solid form includes: dissolving a biodegradable copolymer and an amide-containing compound in water at a first temperature, obtaining a solution; cooling the solution at a second temperature to form a solid mixture; and the solid mixture is subjected to a freeze-drying process at a third temperature.
    Type: Application
    Filed: April 26, 2013
    Publication date: July 3, 2014
    Applicant: Industrial Technology Research Institute
    Inventors: Hsin-Hsin SHEN, Yu-Bing LIOU, Chin-Fu CHEN, Li-Hsin LIN, Hsiu-Hua HUANG, Ying-Hsueh CHAO, Meng-Yow HSIEH, Miao-Tzu CHEN, Chih-Bing HUNG
  • Publication number: 20140161842
    Abstract: A bioresorbable porous film, including a blend mixture of polylactic acid and at least two kinds of polyethylene glycol, wherein the at least two kinds of polyethylene glycol include a first polyethylene glycol, which is in a solid form under ambient temperature and atmospheric pressure, and a second polyethylene glycol, which is in a liquid form under ambient temperature and atmospheric pressure is provided. The film has a porosity of 10%-90%.
    Type: Application
    Filed: April 25, 2013
    Publication date: June 12, 2014
    Applicant: Industrial Technology Research Institute
    Inventors: Li-Hsin LIN, Hsin-Hsin SHEN, Ying-Hsueh CHAO, Hsiu-Hua HUANG, Yu-Bing LIOU, Chih-Bing HUNG, Chin-Fu CHEN