Abstract: A method for creating a fluid barrier in a wellbore or a geological formation surrounding the wellbore includes delivering a plurality of swellable particulates into the wellbore and into a first zone in the wellbore or the formation, the plurality of swellable particulates configured to volumetrically swell to create a fluid barrier in response to exposure to a swelling activator. The method further includes delivering a plurality of fibre elements into the wellbore and into the first zone, the fibre elements configured to adhere to one another to create a web arrangement for constraining movement of the swellable particulates in response to exposure to an adhesion activator.

Abstract: A small molecule conjugate that degrades CDK12/13, and a preparation method therefor and the use thereof. The structure of the small molecule conjugate is: T-L-E, wherein T represents a ligand of a parent nucleus molecule, i.e., a CDK12/13 protein, L represents a moiety linked to T and E, which is also referred to as linker, and E represents a ligand of an E3 ligase. The compound as represented by formula I can be synthesized by means of an amide condensation reaction, a substitution reaction or a click reaction, etc. of a derivative of the T moiety, and an E3 enzyme ligand and a derivative thereof. The compound shows an efficient CDK12/13 degradation activity on a variety of cell lines, a highly specific tumor cell proliferation inhibition activity, and an efficient treatment effect when used in combination with other anti-tumor drugs. In biological and therapeutic aspects, the compound can be used as a lead compound for treating various cancers and other CDK12/13 abnormal diseases.

Abstract: Microenvironment viscositysensitive fluorescent dye, preparation method therefore and use thereof. The fluorescent molecules described in this invention exhibits negligible fluorescence emission in its free state but demonstrates activated fluorescence in high-viscosity microenvironments such as glycerol. It is a new microenvironmental viscosity-sensitive fluorescent dye with obvious viscosity responsiveness, whose fluorescence intensity varies with the viscosity of the microenvironment, and a high viscosity results in a strong fluorescence intensity. Furthermore, the fluorescent molecules exhibit extended emission wavelengths and enhanced brightness while maintaining superior photostability under high-intensity laser excitation, effectively resisting photobleaching. Additionally, this class of dye molecules demonstrates prolonged fluorescence lifetimes that exhibit microenvironment-dependent variations.

Abstract: An electronic device includes: a semiconductor die having opposite first and second sides and a conductive terminal along the first side; a conductive lead electrically coupled to the conductive terminal; a package structure that forms a top side of the electronic device and encloses a portion of the semiconductor die, the package structure including a first molding compound having a first thermal conductivity; and a thermally conductive layer on at least a portion of the second side of the semiconductor die, the thermally conductive layer including a second molding compound having a second thermal conductivity that is greater than the first thermal conductivity.

Abstract: A semiconductor device includes a transistor and an isolation structure. The transistor includes a semiconductor body extending along a first direction and a gate structure coupled with the semiconductor body in a second direction perpendicular to the first direction. The isolation structure is located adjacent to the semiconductor body. The isolation structure includes a first portion extending along the first direction and having at least one air gap therein and a second portion connected with a first end of the first portion along the first direction. The second portion is solid, and a size of the second portion in the reference plane is smaller than a size of the first portion in the reference plane.

Abstract: Apparatus and associated methods relate to a pole-zero balanced power switching regulating system for high power and frequency application. In an illustrative example, a trans-inductor voltage regulator (TLVR) may include at least two phases. For example, each phase may include a current inducing circuit. A second-order current sensing circuit (SOCSC) operably coupled to the TLVR may be configured to measure the current flow of each phase. In some implementations, the TLVR may include a first transfer function with two zeros and one pole and the SOCSC may include a second transfer function with two DCR-poles and one DCR-zero. For example, a difference between corresponding poles and zeros of the first and second transfer functions may effectively cancel each other. For example, a gain and phase difference between the first and the second transfer functions are close to zero. Various embodiments may advantageously allow fast transient current measurement at the TLVR.

Abstract: The present utility model provides a magnetic suspension drain, comprising a first connecting member and a second connecting member that are connected with each other and adapted to respective connection to a drain opening of a drain device and a drain pipe. The magnetic suspension drain further comprises a magnetic suspension inner core arranged in the first connecting member, and the magnetic suspension inner core comprises a rotary floating rod and a rotary sealing cover. The rotary floating rod is provided with a first magnet, and a repulsive second magnet is provided inside the first connecting member.

Abstract: A contact image sensor is provided, including: a control unit configured to receive output pulses from an encoder, where the control unit includes a comparator configured to compare the output pulses with a preset scanning cycle stored in the register to obtain an illumination control signal; an illumination unit configured to illuminate an object to be detected based on the illumination control signal; a scanning unit configured to scan the object to be detected based on the scanning trigger signal to obtain a scanning signal; a data processing unit configured to process the scanning signal to obtain an initial scanning result; and a data output unit configured to obtain a target scanning result based on the initial scanning result and output the target scanning result based on the output trigger signal.

Abstract: An implementation of a memory device includes a stack structure having alternating first layers and dielectric layers. The stack structure has a first surface and a second surface opposite to the first surface. First contact structures include a conductive material. The first contact structures penetrate from the first surface into the stack structure to be in contact respectively with a first portion of first layers. Second contact structures include a conductive material. Each of the second contact structures penetrates from the second surface into the stack structure to be in contact respectively with a remainder portion of conductive layers other than the first portion of the first layers.

Abstract: This application provides a hardware-assisted page table management system and method, a medium, a program product, and a terminal, to achieve efficient address translation through collaborative operation of a memory management unit and a memory cell. The method includes key steps such as translation lookaside buffer hit detection, guest page table lookup, and page walk cache lookup. After receiving an access instruction, the memory management unit performs detection through a translation lookaside buffer hit detection module. If a miss occurs, a guest page table lookup module acquires a corresponding host physical address. The system performs lookup in a page walk cache module, accesses a second-level cache of the memory cell when necessary, and stores a lookup result into a cache line of a preset format.

Abstract: The present disclosure provides a urinal, comprising: a urinal body; a flushing module, configured to flush the urinal body and comprising a flushing pipe; a sterilizing agent supply module, configured to supply a sterilizing agent to the flushing pipe; a sensing module, configured to sense a user of the urinal; and a control module, configured to control the flushing module and the sterilizing agent supply module according to a sensing result of the sensing module. The control module is configured to be capable of controlling the flushing module to start for flushing and controlling the flushing module and the sterilizing agent supply module to start so as to mix the sterilizing agent into water in the flushing pipe for sterilization water flushing. According to the urinal in the present disclosure, automatic flushing and automatic sterilization water flushing can be controlled according to the sensing result of the same sensing module, and a pipeline structure is simple.

Abstract: Provided in the present disclosure are a sensing flushing device with an anti-siphon function, and a sensing urinal. The sensing flushing device comprises: a water intake and output assembly, a water drainage assembly, a solenoid valve assembly and a power supply assembly; and further comprises: a sensing module, which is associated with the solenoid valve assembly and is attached to the water intake and output assembly, wherein the solenoid valve assembly controls the enabling or disabling of flushing in response to a sensing mode of the sensing module; an anti-siphon module, which is associated with the water intake and output assembly and is arranged above the water intake and output assembly, wherein the anti-siphon module is configured to be in communication with a path of the water intake and output assembly when flushing is enabled, and to cut off the path of the water intake and output assembly when flushing is disabled.

Abstract: A composition capable of dissolving inorganic scale in a bore comprises at least one chelating agent and at least one additive capable of enhancing the rate of dissolution of the inorganic scale in the bore. In some embodiments, the at least one additive comprises at least one non-ionic surfactant. In some embodiments, the at least one additive comprises one or more gas generation agents. In some embodiments, the at least one additive comprises at least one biosurfactant.

Abstract: A high-power four-quadrant converter system includes a double-secondary-side oil-immersed rectifier transformer with an output connected to four three-phase bridge type thyristor rectifiers, wherein every two rectifier bridges share a group of rectifier transformer secondary sides; two rectifier bridges sharing a group of rectifier transformer secondary sides are inversely connected in parallel, one of the two rectifier bridges realizes a forward output, and the other one realizes a reverse output; two groups of rectifier bridges which output in the same direction can operate independently or in parallel; when the two groups of rectifier bridges operate in parallel, reactors are connected in parallel to realize current sharing; and the rectifier bridges for the forward output and the reverse output realize free smooth transition under control of a controller, so that a four-quadrant operation of an output current is realized.

Abstract: A method for treating a geological formation surrounding a wellbore includes delivering a first media into the wellbore and into a fracture in the geological formation. The first media includes a plurality of swellable particulates configured to volumetrically swell in response to exposure to a swelling activator. The method includes delivering a second media into the wellbore and into the fracture in the geological formation, the second media being different to the first media and comprising a plurality of proppants. The first media is delivered ahead of the second media such that the swellable particulates are provided in a first region of the fracture towards a fracture tip and the proppants are provided in a second region of the fracture between the first region and the wellbore.

Abstract: A method and system provide the ability to segment a first point cloud. The first point cloud is rendered into multiple two-dimensional (2D) images. The images are segmented to generate a semantic segmentation mask. The images are then backprojected into a 3D classified point cloud. The classified point cloud is segmented into geometric segments and voting is performed for each segment to determine the majority classification and reassign minority classifications. A final point cloud is then exported as a segmented classified point cloud.