Abstract: A lighting apparatus comprises a controller and three lights sources each with a different color temperature. The controller turns on the second light source and the third light source alternately at a strobing frequency between 30 Hz and 65 Hz, resulting in a strobing light (out of the second light source and the third light source) with a combined color temperature approximating the color temperature of the first light source. Alternatively, the lighting apparatus includes a controller and two light sources. The first light source and the second light source operate at different frequencies, resulting in a superimposed light with an operating frequency equal to the difference of these two frequencies. Alternatively, the lighting apparatus turns off one of the two light sources periodically for a short period of time to induce the brain of a subject to better recognize the frequency of the superimposed light.

Abstract: A self-disinfecting photocatalyst sheet includes a substrate material, a photocatalyst layer, and a primer. The photocatalyst layer comprises a primary photocatalyst and a secondary photocatalyst. The primary photocatalyst is anatase titanium dioxide and the secondary photocatalyst comprises a metallic photocatalyst. The secondary photocatalyst absorbs a visible light energy, transfers the energy to the primary photocatalyst, thus activating the primary photocatalyst as the primary disinfecting agent. The substrate material binds the photocatalyst layer by either connecting the primary photocatalyst and/or the secondary photocatalyst through two oxygen atoms of a carboxyl group (COO) comprising the primer, or by forming hydrogen bonds between the carbonyl group and a surface hydroxyl group (OH—) of the primary photocatalyst. The self-disinfecting photocatalyst sheet is activatable by a visible light and can self-disinfect against bacteria and viruses.

Abstract: A self-disinfecting photocatalyst sheet includes a substrate material and a photocatalyst layer with a primary photocatalyst and a secondary photocatalyst. The primary photocatalyst is a metal oxide photocatalyst, whereas the secondary photocatalyst is a metallic photocatalyst. The substrate material binds the photocatalyst layer by either connecting a metal ion of the primary photocatalyst and/or the secondary photocatalyst through two oxygen atoms of a carboxyl group (COO), or by forming hydrogen bonds between a carbonyl group and a surface hydroxyl group (OH?) of the primary photocatalyst. The self-disinfecting photocatalyst sheet is activatable by a visible light and can self-disinfect against bacteria and viruses.

Abstract: A germicidal lighting device includes an ultraviolet (UV) light source, a planar waveguide with a first surface, a second surface opposite to the first surface, and at least one edge surface perpendicular to the two parallel surfaces, and an optical filter. The UV light source is positioned adjacent to the edge surface of the planar waveguide to shine its UV light into the planar waveguide through the edge surface, and the UV light travels in the planar waveguide via total internal reflection. The first surface of the planer waveguide has a mechanism to reflect the UV light at an exit angle to exit the planar waveguide through the second surface. The optical filter filters a portion of the UV. Moreover, the light emitting area of the second surface of the planar waveguide is bigger than the light emitting surface area of the UV light source.

Abstract: A spectral power distribution (SPD) fusion lighting apparatus includes a first visible light source with a first SPD, a second visible light source with a second SPD, a driver circuit, and a controller. The first SPD is different than the second SPD markedly in a 50 nm wavelength range. The controller toggles the turning on of the first visible light and the second visible light at a frequency greater than 25 Hz. The first visible light source is turned on during one half of the duty cycle, whereas the second visible light source is turned on during the other half of the duty cycle. The first visible light source and the second visible light emit similar light outputs and have similar chromaticity coordinates on the CIE 1931 color space chromaticity diagram. In some embodiments a sound wave generator is used to generate a sound wave at the same frequency.

Abstract: A self-disinfecting photocatalyst sheet includes a substrate material and a photocatalyst layer with a primary photocatalyst and a secondary photocatalyst. The primary photocatalyst is a metal oxide photocatalyst, whereas the secondary photocatalyst is a metallic photocatalyst. The substrate material binds the photocatalyst layer by either connecting a metal ion of the primary photocatalyst and/or the secondary photocatalyst through two oxygen atoms of a carboxyl group (COO), or by forming hydrogen bonds between a carbonyl group and a surface hydroxyl group (OH?) of the primary photocatalyst. The self-disinfecting photocatalyst sheet is activatable by a visible light and can self-disinfect against bacteria and viruses.

Abstract: Disclosed herein is an ocular drug delivery system, comprising a positively charged chitosan-modified hydrogel, a secretory phospholipase A2 (sPLA2) hydrolysable liposome encapsulating an anti-inflammatory drug and having a negative surface charge, a first thiolated hyaluronic acid (HA-SH) nanoparticle encapsulating a wound-healing drug and having a negative surface charge, and a second HA-SH nanoparticle encapsulating a transforming growth factor-? inhibitor and having a negative surface charge. The sPLA2 hydrolysable liposome and the first and second HA-SH nanoparticles are attached to the positively charged chitosan-modified hydrogel by electrostatic attraction. Uses of the system are also disclosed.

Abstract: Disclosed herein is an ocular drug delivery system, comprising a positively charged chitosan-modified hydrogel, a secretory phospholipase A2 (sPLA2) hydrolysable liposome encapsulating an anti-inflammatory drug and having a negative surface charge, a first thiolated hyaluronic acid (HA-SH) nanoparticle encapsulating a wound-healing drug and having a negative surface charge, and a second HA-SH nanoparticle encapsulating a transforming growth factor-? inhibitor and having a negative surface charge. The sPLA2 hydrolysable liposome and the first and second HA-SH nanoparticles are attached to the positively charged chitosan-modified hydrogel by electrostatic attraction. Uses of the system are also disclosed.

Abstract: A hollow particle is provided. The hollow particle of the invention comprises (a) a hollow microparticle, (b) a plural of linking molecules binding the surface of the microparticle, (c) a polypeptide binding the linking molecule, and (d) a target molecule binding the linking molecule. The hollow microparticle of the invention can deliver more cells and provides a higher rate of cell transplantation by the hollow structures, polypeptides and target molecules. The present invention also provides a manufacture of the hollow microparticle and a cell carrier.