Abstract: The present invention relates to a novel regulatory T cell protein. This protein, designated PD-L3 OR VISTA resembles members of the PD-L1 family, identified a novel and structurally-distinct, Ig-superfamily inhibitory ligand, whose extracellular domain bears homology to the B7 family ligand PD-L1. This molecule is designated as PD-L3 OR VISTA or V-domain Immunoglobulin Suppressor of T cell Activation (VISTA). Expression of VISTA is primarily within the hematopoietic compartment and is highly regulated on myeloid APCs and T cells. Therapeutic intervention of the VISTA inhibitory pathway represents a novel approach to modulate T cell-mediated immunity for the treatment of a wide variety of cancers, e.g., ovarian, bladder cancer and melanomas. Also, VISTA proteins, especially multimeric VISTA proteins and antibodies may be used to suppress T cell immunity in autoimmune disease, allergy, infection and inflammatory conditions, e.g. multiple sclerosis and arthritic conditions such as RA.

Abstract: Provided is a GABAA receptor agonist phenol derivative that has a novel structure and better efficacy, can effectively reduce side effects, and is safer for clinical use. Specifically disclosed are a compound as represented by the following formula (I), a stereoisomer and pharmaceutically acceptable salt thereof, a pharmaceutical composition containing same, and an application of the compound or composition of the present invention in the central nervous field, thereby providing more and better choices for medicaments for inducing and/or maintaining anesthesia in animal or human bodies, facilitating sedation and hypnosis, and treating and/or preventing anxiety, nausea, vomiting, migraine, convulsion, epilepsy, neurodegenerative diseases, and central nervous system-related diseases.

Abstract: A method includes: obtaining a total data length of an information bit; and obtaining C code blocks based on the total data length of the information bit and a preset first code rate. The C code blocks correspond to one or more code lengths, where the one or more code lengths meet a form of a positive integer power of 2, and where C is a positive integer.

Abstract: A display panel, including: a base substrate including an Under Display Camera (UDC) area and a normal display area located around a periphery of the UDC area, and specifically, the normal display area includes a plurality of sub-pixel driving circuits, and the UDC area includes a plurality of groups of sub-pixels, each of the plurality of groups of sub-pixels including at least two sub-pixels of a same color which have their anodes coupled to each other; and a plurality of first transparent wires, anodes in each group of sub-pixels coupled to a corresponding sub-pixel driving circuit among the plurality of sub-pixel driving circuits through a corresponding first transparent wire among the plurality of first transparent wires.

Abstract: A battery slurry, an electrode plate and a lithium battery are provided. The battery slurry includes an aqueous binder and an organic additive. The organic additive includes at least one of —NHR and —SH, where R is alkyl.

Abstract: The disclosure provides techniques for facilitating video creations. The techniques comprise turning on a first camera on a first side of a terminal; turning on a second camera on a second side of the terminal; capturing, by the first camera, a first video; capturing, by the second camera, a second video; displaying the first video and the second video concurrently, wherein the displaying further comprises displaying the first video in a first area and the second video in a second area during a first time period, and in response to a first instruction to switch video content, displaying the second video in the first area and the first video in the second area during a second time period; and creating a timeline including the first time period, the second time period, and a time stamp of the video content switch in the first area.

Abstract: The embodiments of the present disclosure provide an antibody or antigen-binding fragment against SARS-CoV-2 spike(S) protein, comprising: three complementarity determining regions (HCDRs) of a heavy chain variable region or one or more variants thereof, the heavy chain variable region set forth as SEQ ID NO. 30 or SEQ ID NO. 46, each of the one or more variants having at most two amino acid changes compared to the corresponding CDR; and three complementarity determining regions (LCDRs) of a light chain variable region or one or more variants thereof, the light chain variable region set forth as SEQ ID NO. 32 or SEQ ID NO. 48, each of the one or more variants having at most two amino acid changes compared to the corresponding CDR.

Abstract: A sending device performs first encoding on at least one first code block, to obtain at least one first code word, where each first code block includes a first information block and a first check block for checking the first information block. The sending device performs at least one type of second encoding on at least one second code block, to obtain at least one second code word, where the at least one second code block includes a second check block for checking a portion of information in the at least one second code block, and a code length of the first code word is greater than a code length of the second code word. The sending device generates and sends a data packet that includes the at least one first code word and the at least one second code word.

Abstract: A display panel and a display device are provided. The display panel includes: a base substrate, having a first display region and a second display region, the first display region is located at at least one side of the second display region; a plurality of first pixel circuits, located in the first display region; a plurality of first light-emitting elements, located in the first display region to each drive at least one first light-emitting element; a plurality of second pixel circuits, located in the first display region; a plurality of second light-emitting elements, located in the second display region to each drive at least one second light-emitting element; and a plurality of conductive lines, the second pixel circuit is connected to the second light-emitting element through at least one conductive line.

Abstract: A display substrate and a display device are provided. The display substrate includes a base substrate, at least one group of contact pads, a plurality of first light-emitting elements, a plurality of first pixel driving circuits, a plurality of connecting traces, a plurality of data lines and a plurality of leads. The display area includes a first display area and a second display area; the first light-emitting elements are located in the first display area; the first pixel driving circuits are located in the second display area; the leads are located in the first display area and the peripheral area, and connect the data lines and the at least one group of contact pads; orthographic projections of the first light-emitting elements on a substrate surface of the base substrate are at least partly overlapped with orthographic projections of the leads on the substrate surface of the base substrate.

Abstract: A display panel (10) includes a circuit backplane (1) and a reflective layer (3). The circuit backplane (1) includes a first main surface (11), a second main surface (12), and a plurality of side surfaces (13). The second main surface (12) is disposed opposite to the first main surface (11). The side surfaces (13) each connect the first main surface (11) and the second main surface (12). At least one side surface in the plurality of side surfaces (13) is a selected side surface (13a). The selected side surface (13a) is covered by the reflective layer (3), the reflective layer (3) being configured to be removed under a predetermined process condition.

Abstract: The display substrate includes: a display area and a bezel area, the display area including a first display area and a second display area; first light emitting devices in the first display area and second light emitting devices in the second display area; first pixel drive circuits in the bezel area and second pixel drive circuits in the second display area, the first pixel drive circuits are connected to the first light emitting devices, and the second pixel drive circuits are connected to the second light emitting devices; and data lines in the second display area, each data line being connected to the first pixel drive circuits and the second pixel drive circuits which are respectively electrically connected to a column of first light emitting devices and a column of second light emitting devices, which are in the same column.

Abstract: The present invention discloses a system for providing mobile power, in which the required equipment for the power supply system at fracturing fields as well as connection cables and connection hoses are integrated properly, assigned onto three transport vehicles for movement and effectively connected. Intake components and a turbine generation system are combined on a first transport vehicle and installed together, then transported to customer sites directly, thus saving the installation time at the user sites. The two different designs on the locations of an exhaust stack and an exhaust silencer not only meet the requirements of road transportation, but also meet the requirements of exhaust gas emission during operations.

Abstract: A display substrate. In a plane parallel to the display substrate, the display substrate includes a plurality of sub-pixels, at least one sub-pixel includes a pixel driving circuit and a light emitting device connected to the pixel driving circuit, the pixel driving circuit at least includes a storage capacitor and a plurality of transistors, the plurality of transistors at least includes a driving transistor and at least one switching transistor of a dual-gate structure. In a plane perpendicular to the display substrate, the display substrate includes a plurality of conductive layers, the first polar plate and the gate electrode of the drive transistor are arranged in the same layer, the second polar plate and the first power line are arranged in the same layer.

Abstract: A large-load unmanned aerial vehicle (UAV) for plant protection with adjustable spraying swath and pesticide application amount is provided, relating to the technical field of pesticide application of unmanned aerial vehicles. The large-load unmanned aerial vehicle for plant protection comprises a large-load unmanned aerial vehicle, a pesticide box, a variable pesticide application system, and adjustable spraying swath mechanisms, wherein the pesticide box is fixed to landing gears of the unmanned aerial vehicle and is positioned below a control platform of the unmanned aerial vehicle; the adjustable spraying swath mechanisms are arranged on the landing gears, the variable pesticide application system is connected with the pesticide box and the adjustable spraying swath mechanisms, the variable pesticide application system and the adjustable spraying swath mechanisms are electrically connected with the control platform, and the control platform is in communication connection with a remote control handle.

Abstract: A lifting device for building a steel structure hoistway and a method for building a steel structure hoistway. The lifting device includes a lifting mechanism and a crane mechanism. The lifting mechanism includes a bottom platform, a middle platform and a top platform. The crane mechanism is arranged on the top platform of the lifting mechanism, and includes a base and a crane on the base. The base is arranged on the top platform and is rotatable relative to the top platform along a vertical axis, and the hanger frame of the crane is movable between a vertical orientation and an inclined orientation. The lifting mechanism is configured to ascend and descend in the constructed steel structure hoistway, and the crane mechanism is configured to lift building materials, such as steel beams, steel columns, etc., for use in building the steel structure hoistway to their designed installation locations.

Abstract: A display substrate and a display device are provided. In the display substrate, a first display region includes a first light emitting unit column and a second light emitting unit column each connected with a column of first sub-pixel circuits; a second display region includes a third light emitting unit column and a fourth light emitting unit column each connected with a column of first sub-pixel circuit pairs; each second sub data line is connected with each second light emitting unit column, and each fourth sub data line is connected with each fourth light emitting unit column. The first sub-pixel circuits connected with the fourth light emitting unit column and the first sub-pixel circuits connected with the second light emitting unit column are located in different columns, and the second sub data line and the fourth sub data line are connected by a data line connection portion.