Abstract: The present disclosure provides methods for treating hematological malignancies and Ewing's sarcoma using menin inhibitors. Compositions for use in these methods are also provided.

Abstract: A vehicle brake system, includes a brake fluid control assembly and a brake master cylinder assembly. The brake fluid control assembly a manifold block, and a pressure buildup device mounted at the manifold block. The brake master cylinder assembly is in communication with the manifold block. The brake master cylinder assembly and the pressure buildup device drive brake fluid to be output via the manifold block. A central axis of the brake master cylinder assembly is non-perpendicular to a first axis along a movement direction of a piston of the pressure buildup device.

Abstract: Provided is a method for preparing a trifluoromethyl aromatic compound, including: mixing a trichloromethyl aromatic compound with an organic alkali hydrofluoride to obtain a mixture, and subjecting the mixture to fluorination to obtain a reaction solution; subjecting the reaction solution to solid-liquid separation to obtain an organic alkali hydrochloride wet product and a filtrate, drying the organic alkali hydrochloride wet product, and condensing and recycling a gas generated during the drying to obtain a condensed product; and purifying the filtrate and the condensed product by rectification to obtain the trifluoromethyl aromatic compound.

Abstract: Disclosed are an oxadiazole compound having a structure of formula (I), a pharmaceutical composition comprising same, and the use thereof as an HDAC6 inhibitor.

Abstract: Disclosed is a trifluoromethyl-substituted sulfonamide BCL-2-selective inhibitor, in particular disclosed are a compound of formula I, a stereoisomer or a pharmaceutically acceptable salt thereof, a preparation method therefore, and a pharmaceutical composition thereof. Also disclosed are the uses of said compound and of a pharmaceutical composition comprising same for treating anti-apoptotic BCL-2-related diseases, such as cancer.

Abstract: The present invention belongs to the field of pharmaceuticals, and particularly relates to a tricyclic compound, a method for preparing same, and use thereof. In particular, the present invention relates to a compound represented by formula (I) or a pharmaceutically acceptable salt, ester, stereoisomer, tautomer, polymorph, solvate, N-oxide, isotope-labeled compound, metabolite or prodrug thereof, a method for preparing same, a pharmaceutical composition comprising same, and uses thereof.

Abstract: Monoorgano tin trialkoxide compounds having chemical formula R?SnX3 and containing less than about 5 mol % R?2SnX2 are described. R? is an optionally substituted organic substituent having about 1 to about 20 carbon atoms and each X is independently ORf, wherein Rf is a fluorinated organic substituent having about 1 to about 20 carbon atoms. Methods for synthesizing and purifying these compounds are also provided. The monoorgano tin compounds may be used for the formation of high-resolution EUV lithography patterning precursors and are attractive due to their high purity and minimal concentration of diorgano tin impurities.

Abstract: Apparatus and methods for bandgap reference generators are disclosed. In certain embodiments, a bandgap reference generator includes a low voltage bandgap reference circuit that generates a first bandgap reference voltage, a high voltage bandgap reference circuit that generates a second bandgap reference voltage, a bandgap selector circuit that outputs the first bandgap reference voltage or the second bandgap reference voltage as a selected bandgap reference voltage based on a voltage level of the power supply voltage, and a bandgap translator circuit that generates an output bandgap reference voltage based on the selected bandgap reference voltage.

Abstract: Composite materials with good electrical conductivity at low metal loadings are prepared using flowable, curable ink compositions that include polymer matrix precursor, silver nanowires, and reducible metal ions such as silver ions. The composite materials as electrically conductive structures can include up to about 20 wt % total metal and exhibit resistivity of no more than about 500 Ohm-cm. The electrically conductive structures can be designed to exhibit a variety of performance features, for example, the structures can be opaque or translucent, or they can have a total transmittance of visible light of at least about 80%.

Abstract: A light strip assembly, a backlight module, and a display device are provided. The light strip assembly includes: a light board, provided with at least two different types of light-emitting unit arrays, where each type of light-emitting unit array includes a plurality of light-emitting units, different types of light-emitting units are configured to emit lights with different wavelengths, and wirings of the plurality of light-emitting units of each type of light-emitting unit array are integrated into an outlet terminal; and a control circuit board, provided with at least two connectors, where different connectors are connected to the outlet terminals of the different types of light-emitting unit arrays in one-to-one correspondence to control lighting ratios of the light-emitting units of the different types of light-emitting unit arrays.

Abstract: An unsupervised region-growing network (RGN) is trained to perform object segmentation on video data degraded by atmospheric turbulence. The method includes obtaining input data containing turbulence-degraded video, extracting a video frame sequence, and training the RGN using a selected algorithm incorporating a region-growing algorithm and a grouping loss function. A bidirectional optical flow sequence is computed for multiple reference frames within the video sequence. Pixel-level masks are generated for detected moving objects, followed by applying the region-growing algorithm to create coarse masks. A grouping loss function refines these masks to ensure consistency across consecutive frames. The trained RGN outputs refined masks as object segmentation data for the received video, improving segmentation accuracy in turbulent environments.

Abstract: According to implementations of the subject matter described herein, there is provided a solution for semantic representation of text in a document. In this solution, textual information comprising a sequence of text elements and layout information of the text element are determined from a document. The layout information indicates a spatial arrangement of the plurality of text elements presented within the document. Based at least in part on the plurality of text elements and the layout information, respective semantic feature representations of the plurality of text elements are generated. By jointly using both the textual information and the layout information, rich semantics of the text elements in the document can be effectively captured in the feature representations.

Abstract: A data fusion method and apparatus, and a device and a storage medium are provided. The method includes: acquiring, from a first data center, a plurality of pieces of first data to be compared that are within a preset time period, and acquiring, from a second data center, a plurality of pieces of second data to be compared that are within the preset time period; then, determining the same data unique identifier in the plurality of pieces of first data to be compared and the plurality of pieces of second data to be compared, and taking the same data unique identifier as a first data identifier; and acquiring first data to be compared that corresponds to the first data identifier, and acquiring second data to be compared that corresponds to the first data identifier.

Abstract: A method for repairing copper and low-k dielectric films on a substrate is provided. In some embodiments, the method includes positioning the substrate within a process chamber, introducing a reducing agent into the process chamber to remove copper oxide from a copper layer on the substrate, removing the reducing agent from the process chamber, and introducing a recovery precursor into the process chamber to decrease a k value of a low-k film on the substrate.

Abstract: Exemplary semiconductor processing methods may include providing a first etchant precursor to a processing region of a semiconductor processing chamber. A substrate may be housed within the processing region. A first layer of silicon-and-germanium-containing material, a second layer of silicon-and-germanium-containing material, and a layer of silicon-containing material may be disposed on the substrate. The methods may include providing a passivation precursor to the processing region. The methods may include contacting the substrate with the first etchant precursor and the passivation precursor. The contacting may selectively etch the first layer of silicon-and-germanium-containing material. The contacting may form a passivation material on the substrate.

Abstract: Embodiments of this application provide a chip system and a collective communication method, and relate to the field of chip technologies. A specific solution is: The chip system includes a processor core, a task scheduler, and a first accelerator. The processor core is configured to: orchestrate all tasks of collective communication in an expected execution sequence, to obtain an orchestrated execution sequence of the tasks, and deliver the orchestrated execution sequence of the tasks and a synchronization task to the task scheduler, where the synchronization task is used to control the orchestrated execution sequence of the tasks. The task scheduler is configured to: schedule the tasks to the first accelerator in the orchestrated execution sequence of the tasks, and control the orchestrated execution sequence of the tasks based on the synchronization task. The first accelerator is configured to execute the tasks in the orchestrated execution sequence of the tasks.

Abstract: The present application provides a current collector, a secondary battery and a power consuming device. The current collector is divided into a first region and a second region, wherein the first region is in contact with the second region, and the first region has an elastic modulus greater than that of the second region.

Abstract: The embodiments of the present application provide a method, apparatus and system for thermal runaway processing and a storage medium. The method first obtains a battery parameter for each of a plurality of battery modules in a power battery pack, then determines that a thermal runaway is occurred in a first battery module based on the battery parameter for each of the plurality of battery modules; and then obtains a second battery module based on the first battery module, wherein the second battery module corresponds to at least one battery module excluding the first battery module in the power battery pack; and finally supplies power to a chiller system with the second battery module.

Abstract: The present application provides a protection case of an intelligent terminal. The protection case of the intelligent terminal includes a housing, a base, a RFID coil, at least one RFID chip and at least one switching element. A first surface of the housing defines a mounting groove, and a second surface of the housing defines a positioning groove. The base is disposed in the mounting groove, and the RFID coil is at least partially disposed on the base. The at least one RFID chip is disposed in the mounting groove and electrically connected to the RFID coil. The at least one switching element is disposed in the positioning groove, and one of the at least one switching element is connected to a circuit where one of the at least one RFID chip is connected with the RFID coil.

Abstract: This application relates to the field of communication technologies, and discloses a communication method and apparatus. The method includes: performing layering on first data, to obtain N layers of data, where N is an integer greater than or equal to 2; receiving modulation and coding indication information from a second communication apparatus, where the modulation and coding indication information indicates an MCS corresponding to each layer of data in P layers of data, the P layers of data belong to the N layers of data, and the MCS corresponding to each layer of data in the P layers of data; and separately performing coding and modulation on the P layers of data based on the MCS corresponding to each layer of data in the P layers of data.