Patents by Inventor Li-Qiang Sun

Li-Qiang Sun has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Hepatitis C Virus Inhibitors
    Publication number: 20080119461
    Abstract: Hepatitis C virus inhibitors having the general formula are disclosed. Compositions comprising the compounds and methods for using the compounds to inhibit HCV are also disclosed.
    Type: Application
    Filed: November 5, 2007
    Publication date: May 22, 2008
    Inventors: Ny Sin, Brian Lee Venables, Li-Qiang Sun, Sing-Yuen Sit, Yan Chen, Paul Michael Scola
  • Hepatitis C Virus Inhibitors
    Publication number: 20080014173
    Abstract: Hepatitis C virus inhibitors having the general formula are disclosed. Compositions comprising the compounds and methods for using the compounds to inhibit HCV are also disclosed.
    Type: Application
    Filed: July 10, 2007
    Publication date: January 17, 2008
    Inventors: Paul Michael Scola, Li-Qiang Sun
  • Hepatitis C virus inhibitors
    Publication number: 20070010455
    Abstract: The present disclosure relates to tripeptide compounds, compositions and methods for the treatment of hepatitis C virus (HCV) infection. Also disclosed are pharmaceutical compositions containing such compounds and methods for using these compounds in the treatment of HCV infection.
    Type: Application
    Filed: July 6, 2006
    Publication date: January 11, 2007
    Inventors: Piyasena Hewawasam, Min Ding, Li-Qiang Sun, Paul Scola
  • Arylcyclopropylcarboxylic amides as potassium channel openers
    Patent number: 7144881
    Abstract: The present invention provides novel arylcyclopropylcarboxylic amides and related derivatives having the general Formula I wherein R, R1, R2, R3, R4, R5, R6 and R7 are as defined in the specification, or a nontoxic pharmaceutically acceptable salt, solvate or hydrate thereof which are openers or activators of KCNQ potassium channels. The present invention also provides pharmaceutical compositions comprising said arylcyclopropylcarboxylic amides and to the method of treatment of disorders sensitive to KCNQ potassium channel opening activity such as migraine or a migraine attack, bipolar disorders, epilepsy, acute and chronic pain and anxiety.
    Type: Grant
    Filed: November 21, 2003
    Date of Patent: December 5, 2006
    Assignee: Bristol-Myers Squibb Company
    Inventors: Yong-Jin Wu, Alexandre L'Heureux, Li-Qiang Sun
  • Hepatitis C virus inhibitors
    Patent number: 7135462
    Abstract: Hepatitis C virus inhibitors are disclosed having the general formula: wherein A, R2, R3, R?, B and Y are described in the description. Compositions comprising the compounds and methods for using the compounds to inhibit HCV are also disclosed.
    Type: Grant
    Filed: November 18, 2004
    Date of Patent: November 14, 2006
    Assignee: Bristol-Myers Squibb Company
    Inventors: Paul Michael Scola, Jeffrey Allen Campbell, Ny Sin, Li-Qiang Sun, Xiangdong Alan Wang
  • 3-(pyridinyl-piperazin-1-yl)-phenylethyl amides as potassium channel openers
    Patent number: 7087609
    Abstract: The present invention provides piperazinyl phenylethyl amides and related derivatives having the general Formula I wherein R1, R2, R3, R4, R5, R6, A and B are as defined in the specification, or a nontoxic pharmaceutically acceptable salt, solvate or hydrate thereof which are openers or activators of KCNQ potassium channels. The present invention also provides pharmaceutical compositions comprising said piperazinyl phenylethyl amides and to the method of treatment of disorders sensitive to KCNQ potassium channel opening activity such as migraine or a migraine attack, bipolar disorders, epilepsy, acute and chronic pain, and anxiety.
    Type: Grant
    Filed: November 21, 2003
    Date of Patent: August 8, 2006
    Assignee: Bristol-Myers Squibb Company
    Inventors: Yong-Jin Wu, Li-Qiang Sun, Jie Chen
  • Hepatitis C virus inhibitors
    Publication number: 20060172950
    Abstract: Hepatitis C virus inhibitors are disclosed having the general formula: wherein R1, R2, R3, R?, B, Y and X are described in the description. Compositions comprising the compounds and methods for using the compounds to inhibit HCV are also disclosed.
    Type: Application
    Filed: December 7, 2005
    Publication date: August 3, 2006
    Inventors: Xiangdong Wang, Li-Qiang Sun, Sing-Yuen Sit, Ny Sin, Paul Scola, Piyasena Hewawasam, Andrew Good, Yan Chen, Jeffrey Campbell
  • 1-aryl-2-hydroxyethyl amides as potassium channel openers
    Patent number: 7045551
    Abstract: The present invention provides novel aryl hydroxyethyl amides and related derivatives having the general Formula I wherein R1, R2, R3, R4, R5, R6, R7 and A are as defined in the specification, or a nontoxic pharmaceutically acceptable salt, solvate or hydrate thereof which are openers or activators of KCNQ potassium channels. The present invention also provides pharmaceutical compositions comprising said aryl hydroxyethyl amides and to the method of treatment of disorders sensitive to KCNQ potassium channel opening activity such as migraine or a migraine attack, bipolar disorders, epilepsy, acute and chronic pain and anxiety.
    Type: Grant
    Filed: November 21, 2003
    Date of Patent: May 16, 2006
    Assignee: Bristol-Myers Squibb Company
    Inventors: Yong-Jin Wu, Li-Qiang Sun, Huan He, Alexandre L'Heureux
  • Hepatitis C virus inhibitors
    Patent number: 6995174
    Abstract: Hepatitis C virus inhibitors are disclosed having the general formula: wherein R1, R2, R3, R?, B, Y and X are described in the description. Compositions comprising the compounds and methods for using the compounds to inhibit HCV are also disclosed.
    Type: Grant
    Filed: May 20, 2003
    Date of Patent: February 7, 2006
    Assignee: Bristol-Myers Squibb Company
    Inventors: Xiangdong Alan Wang, Li-Qiang Sun, Sing-Yuen Sit, Ny Sin, Paul Michael Scola, Piyasena Hewawasam, Andrew Charles Good, Yan Chen, Jeffrey Allen Campbell
  • Hepatitis C virus inhibitors
    Publication number: 20050267040
    Abstract: Hepatitis C virus inhibitors are having the general formula: wherein A, R2, R3, R?, B and Y are described in the description. Compositions comprising the compounds and methods for using the compounds to inhibit HCV are also disclosed.
    Type: Application
    Filed: November 18, 2004
    Publication date: December 1, 2005
    Inventors: Paul Scola, Jeffrey Campbell, Ny Sin, Li-Qiang Sun, Xiangdong Wang
  • Pyridinyl, pyrimidinyl and pyrazinyl amides as potassium channel openers
    Patent number: 6900210
    Abstract: The present invention provides novel heterocyclic amides and related derivatives having the general Formula I wherein R1, R2, R3, R4, R5, R6, A, B and Z are as defined in the specification, or a nontoxic pharmaceutically acceptable salt, solvate or hydrate thereof which are openers or activators of KCNQ potassium channels. The present invention also provides pharmaceutical compositions comprising said heterocyclic amides and to the method of treatment of disorders sensitive to KCNQ potassium channel opening activity such as migraine or a migraine attack, bipolar disorders, epilepsy, acute and chronic pain and anxiety.
    Type: Grant
    Filed: November 21, 2003
    Date of Patent: May 31, 2005
    Assignee: Bristol-Myers Squibb Company
    Inventors: Yong-Jin Wu, Li-Qiang Sun, Jie Chen, Huan He
  • 1-aryl-2-hydroxyethyl amides as potassium channel openers
    Publication number: 20040122007
    Abstract: The present invention provides novel aryl hydroxyethyl amides and related derivatives having the general Formula I 1
    Type: Application
    Filed: November 21, 2003
    Publication date: June 24, 2004
    Inventors: Yong-Jin Wu, Li-Qiang Sun, Huan He, Alexandre L'Heureux
  • 3-(Pyridinyl-piperazin-1-yl)-phenylethyl amides as potassium channel openers
    Publication number: 20040110765
    Abstract: The present invention provides piperazinyl phenylethyl amides and related derivatives having the general Formula I 1
    Type: Application
    Filed: November 21, 2003
    Publication date: June 10, 2004
    Inventors: Yong-Jin Wu, Li-Qiang Sun, Jie Chen
  • Arylcyclopropylcarboxylic amides as potassium channel openers
    Publication number: 20040110754
    Abstract: The present invention provides novel arylcyclopropylcarboxylic amides and related derivatives having the general Formula I 1
    Type: Application
    Filed: November 21, 2003
    Publication date: June 10, 2004
    Inventors: Yong-Jin Wu, Li-Qiang Sun, Alexandre L'Heureux
  • Hepatitis C virus inhibitors
    Publication number: 20040106559
    Abstract: Hepatitis C virus inhibitors are disclosed having the general formula: 1
    Type: Application
    Filed: May 20, 2003
    Publication date: June 3, 2004
    Inventors: Xiangdong Alan Wang, Li-Qiang Sun, Sing-Yuen Sit, Ny Sin, Paul Michael Scola, Piyasena Hewawasam, Andrew Charles Good, Yan Chen, Jeffrey Allen Campbell
  • Pyridinyl, pyrimidinyl and pyrazinyl amides as potassium channel openers
    Publication number: 20040102449
    Abstract: The present invention provides novel heterocyclic amides and related derivatives having the general Formula I 1
    Type: Application
    Filed: November 21, 2003
    Publication date: May 27, 2004
    Inventors: Yong-Jin Wu, Li-Qiang Sun, Jie Chen, Huan He
  • Benzoxazole derivatives as novel melatonergic agents
    Patent number: 6737431
    Abstract: Novel benzoxazole derivatives which have a binding affinity for the human melatonin receptor and, therefore, are useful as melatonergic agents.
    Type: Grant
    Filed: March 6, 2003
    Date of Patent: May 18, 2004
    Assignee: Bristol-Myers Squibb Company
    Inventors: Katherine S. Takaki, Li-Qiang Sun, Graham Johnson, Stephen R. Bertenshaw, Derek Denhart, Jie Chen
  • Benzoxazole derivatives as novel melatonergic agents
    Publication number: 20030216456
    Abstract: Novel benzoxazole derivatives which have a binding affinity for the human melatonin receptor and, therefore, are useful as melatonergic agents.
    Type: Application
    Filed: March 6, 2003
    Publication date: November 20, 2003
    Inventors: Katherine S. Takaki, Li-Qiang Sun, Graham Johnson, Stephen R. Bertenshaw, Derek Denhart, Jie Chen
  • 5-HT7 receptor antagonists
    Patent number: 6630469
    Abstract: Amino-pyrimidine and amino-triazine derivatives having 5-HT7 antagonist activity for the treatment of sleeping disorders, depression, schizophrenia, anxiety, obsessive compulsive disorders, circadian rhythm disorders, ocular disorders and/or centrally and peripherally mediated hypertension are provided.
    Type: Grant
    Filed: April 24, 2001
    Date of Patent: October 7, 2003
    Assignee: Bristol-Myers Squibb Company
    Inventors: Michael A. Poss, Ashok V. Purandare, Ronald J. Mattson, Li-Qiang Sun
  • 5-HT7 receptor antagonists
    Publication number: 20020032199
    Abstract: Amino-pyrimidine and amino-triazine derivatives having 5-HT7 antagonist activity for the treatment of sleeping disorders, depression, schizophrenia, anxiety, obsessive compulsive disorders, circadian rhythm disorders, ocular disorders and/or centrally and peripherally mediated hypertension are provided.
    Type: Application
    Filed: April 24, 2001
    Publication date: March 14, 2002
    Inventors: Michael A. Poss, Ashok V. Purandare, Ronald J. Mattson, Li-Qiang Sun