Patents by Inventor Li-Ru Zhao

Li-Ru Zhao has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHOD OF TREATING CEREBRAL AUTOSOMAL DOMINANT ARTERIOPATHY WITH SUBCORTICAL INFARCT AND LEUKOENCEPHALOPATHY (CADASIL)
    Publication number: 20230033523
    Abstract: The present disclosure relates to a method of improving neurological function and enhancing cerebrovascular maintenance and regeneration in a mammal suffering from cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL), including administering an effective amount of a composition including a granulocyte colony-stimulating factor (G-CSF) polypeptide in combination with a stem cell factor (SCF) polypeptide.
    Type: Application
    Filed: July 30, 2021
    Publication date: February 2, 2023
    Inventors: Li-Ru Zhao, Suning Ping
  • Peptide amphiphile suspension to prevent or reduce tumor formation from administered embryonic stem cells
    Patent number: 8697048
    Abstract: The present invention relates to the use of self-assembling peptide amphiphiles to prevent tumor formation by transplanted stem cells. The present invention further relates to the use of self-assembling peptide amphiphiles to treat cancers.
    Type: Grant
    Filed: December 21, 2011
    Date of Patent: April 15, 2014
    Assignee: Northwestern University
    Inventors: Li-Ru Zhao, John A. Kessler
  • Use of SCF and G-CSF in the treatment of cerebral ischemia and neurological disorders
    Patent number: 8524655
    Abstract: The present invention relates to the use of stem cell factor (SCF) polypeptide, alone and in combination with granulocyte colony stimulating factor (G-CSF) polypeptide, in the prevention or treatment of injury to the brain after cerebral ischemia or neurological disorder. More particularly, the invention provides methods of improving neurological function and outcome after stroke by the administration of SCF polypeptide, alone and in combination with G-CSF polypeptide. This treatment can be used alone or in combination with other well-known methods of treatment of cerebral ischemia and neurological disorders in a mammal.
    Type: Grant
    Filed: February 26, 2010
    Date of Patent: September 3, 2013
    Assignee: Northwestern University
    Inventors: Li-Ru Zhao, John Kessler, Seema Singhal, Jayesh Mehta
  • COMPOSITIONS AND METHODS FOR CONTROLLING STEM CELL AND TUMOR CELL DIFFERENTIATION, GROWTH, AND FORMATION
    Publication number: 20120093784
    Abstract: The present invention relates to the use of self-assembling peptide amphiphiles to prevent tumor formation by transplanted stem cells. The present invention further relates to the use of self-assembling peptide amphiphiles to treat cancers.
    Type: Application
    Filed: December 21, 2011
    Publication date: April 19, 2012
    Applicant: NORTHWESTERN UNIVERSITY
    Inventors: Li-Ru Zhao, John A. Kessler
  • Use of SCF and G-CSF in the Treatment of Cerebral Ischemia and Neurological Disorders
    Publication number: 20100286039
    Abstract: The present invention relates to the use of stem cell factor (SCF) polypeptide, alone and in combination with granulocyte colony stimulating factor (G-CSF) polypeptide, in the prevention or treatment of injury to the brain after cerebral ischemia or neurological disorder. More particularly, the invention provides methods of improving neurological function and outcome after stroke by the administration of SCF polypeptide, alone and in combination with G-CSF polypeptide. This treatment can be used alone or in combination with other well-known methods of treatment of cerebral ischemia and neurological disorders in a mammal.
    Type: Application
    Filed: February 26, 2010
    Publication date: November 11, 2010
    Applicant: NORTHWESTERN UNIVERSITY
    Inventors: Li-Ru Zhao, John Kessler, Seema Singhal, Jayesh Mehta
  • Use of SCF and G-CSF in the treatment of cerebral ischemia and neurological disorders
    Publication number: 20060153799
    Abstract: The present invention relates to the use of stem cell factor (SCF) polypeptide, alone and in combination with granulocyte colony stimulating factor (G-CSF) polypeptide, in the prevention or treatment of injury to the brain after cerebral ischemia or neurological disorder. More particularly, the invention provides methods of improving neurological function and outcome after stroke by the administration of SCF polypeptide, alone and in combination with G-CSF polypeptide. This treatment can be used alone or in combination with other well-known methods of treatment of cerebral ischemia and neurological disorders in a mammal.
    Type: Application
    Filed: November 4, 2005
    Publication date: July 13, 2006
    Applicant: NORTHWESTERN UNIVERSITY
    Inventors: Li-Ru Zhao, John Kessler, Seema Singhal, Mehta Jayesh
  • Compositions and methods for controlling stem cell and tumor cell differentiation, growth, and formation
    Publication number: 20050214257
    Abstract: The present invention relates to the use of self-assembling peptide amphiphiles to prevent tumor formation by transplanted stem cells. The present invention further relates to the use of self-assembling peptide amphiphiles to treat cancers.
    Type: Application
    Filed: December 21, 2004
    Publication date: September 29, 2005
    Applicant: Northwestern University
    Inventors: Li-Ru Zhao, John Kessler