Abstract: The present invention provides a method for preparing a chiral 4-aryl-?-amino acid derivative. The preparation method comprises hydrogenating an enamine compound having a structure as shown in Formula III in an organic solvent in the presence of a catalyst containing a transition metal and BIBOPs. The preparation method of the present invention uses a small amount of a selected asymmetric catalyst, and has a simple operation, mild reaction conditions, a high yield, a high stereoselectivity, and better industrial application and economic values.

Abstract: Mechanisms are provided for a user equipment (UE) to determine to use a shared resource such as an antenna to access a land based wireless communication system or a satellite communication system. The UE can provide a first priority indication to indicate whether to access the land based wireless communication system based on one or more wireless link metrics of the land based wireless communication system or one or more application metrics for applications using the land based wireless communication system; and provide a second priority indication to indicate whether to access the satellite wireless communication system based on one or more service metrics provided by the satellite wireless communication system. The UE can determine to use the shared resources to access the land based wireless communication system or the satellite communication system based on the first priority indication and the second priority indication.

Abstract: Provided are a water and acid adsorbing battery separator and a preparation method therefor, a water and acid adsorbing electrode plate, and a battery. A metal organic framework material is used and scrape-coated on a battery separator to prepare a composite separator, which can efficiently adsorb impurities such as water/acid from a battery, as a water and acid adsorbing battery separator. In one aspect, the water and acid adsorbing battery separator can effectively improve the cycling stability of a battery by adsorbing impurities such as water and an acid from the battery. In another aspect, the water and acid adsorbing battery separator can reduce control conditions of water during a battery assembly process, thereby effectively reducing the cost.

Abstract: Disclosed are an aromatic heterocyclic compound and an application thereof. The aromatic heterocyclic compound is represented by formula I, and the compound has good LSD1 enzyme inhibitory activity, and can be used as an LSD1 inhibitor for treatment of tumors etc.

Abstract: The present disclosure provides a purification method for 3-amino-5-methylpiperidine with amino protected by Boc. The method includes adding a solvent to the crude product of 3-amino-5-methylpiperidine with amino protected by Boc, heating until it is dissolved to obtain a mixed solution; adding an acid and an amine crystallization auxiliary to the mixed solution, stirring and dispersing to obtain a dispersed solution; cooling the dispersed solution until crystallization, separating and drying same to obtain a salt crystal of 3-amino-5-methylpiperidine with amino protected by Boc. The present disclosure improves the product characters of 3-amino-5-methylpiperidine with amino protected by Boc after salifying and crystallization, thereby improving the yield and purity of the product, at the same time, it simplifies the operation steps of salifying and crystallization of 3-amino-5-methylpiperidine with amino protected by Boc, shortens the operation time, and reduces production costs.

Abstract: Provided in the present disclosure are a nemonoxacin malate active pharmaceutical ingredient with low combination impurities, and a preparation method thereof, specifically, provided in the present disclosure is a method for preparing the nemonoxacin malate active pharmaceutical ingredient, the method includes the following steps: 1) providing a C1-C3 alcohol/water mixed solvent in which nemonoxacin free base (Formula II) and D,L-malic acid are dissolved; and 2) performing cooling crystallization on a mixed solution obtained in the step 1), and then performing solid-liquid separation, washing and drying on a precipitated solid, so as to obtain the nemonoxacin malate active pharmaceutical ingredient.

Abstract: The present disclosure discloses a method for synthesizing quinolones intermediates by a continuous flow reaction. Specifically, according to the method, a microchannel reactor is used, which improves the selectivity and conversion rate of the reaction, and the conversion rate of compound ii is increased to more than 95% and the yield is increased to more than 85%; avoids the use of a solvent such as methanol, and methyl tert-butyl ether, etc., in the intermittent reaction process, which simplifies the post-processing method, shortens the overall operation time from about 24 hours to a few minutes, greatly improving the production efficiency, and realizing the continuity and automation of the whole process; and thus makes the product have high purity and high yield, which is suitable for industrial production.

Abstract: The present invention belongs to the technical field of oil field drilling, and relates to a ground testing device for a stabilized platform of a rotary steerable drilling tool. The ground testing device includes: a first supporting member and a second supporting member that are oppositely arranged, where the second supporting member is provided with a first mounting hole; a drill collar and a drill collar motor mounted outside the first supporting member, where a motor shaft of the drill collar motor penetrates the first supporting member and is connected to the drill collar, and a stabilized platform mounting assembly is arranged inside the drill collar; and a first vibration member connected to the drill collar and a second vibration member arranged in the first mounting hole in a sleeved manner, where an elastic member is arranged between the second vibration member and the second supporting member, and the elastic member is arranged on the second vibration member in a sleeving manner.

Abstract: The present invention belongs to the technical field of oil field drilling, and relates to a ground testing device for a stabilized platform of a rotary steerable drilling tool. The ground testing device includes: a first supporting member and a second supporting member that are oppositely arranged, where the second supporting member is provided with a first mounting hole; a drill collar and a drill collar motor mounted outside the first supporting member, where a motor shaft of the drill collar motor penetrates the first supporting member and is connected to the drill collar, and a stabilized platform mounting assembly is arranged inside the drill collar; and a first vibration member connected to the drill collar and a second vibration member arranged in the first mounting hole in a sleeved manner, where an elastic member is arranged between the second vibration member and the second supporting member, and the elastic member is arranged on the second vibration member in a sleeving manner.

Abstract: Provided in the present disclosure are a nemonoxacin malate active pharmaceutical ingredient with low combination impurities, and a preparation method thereof, specifically, provided in the present disclosure is a method for preparing the nemonoxacin malate active pharmaceutical ingredient, the method includes the following steps: 1) providing a C1-C3 alcohol/water mixed solvent in which nemonoxacin free base (Formula II) and D,L-malic acid are dissolved; and 2) performing cooling crystallization on a mixed solution obtained in the step 1), and then performing solid-liquid separation, washing and drying on a precipitated solid, so as to obtain the nemonoxacin malate active pharmaceutical ingredient.

Abstract: The present invention provides a method for preparing a chiral 4-aryl-?-amino acid derivative. The preparation method comprises hydrogenating an enamine compound having a structure as shown in Formula III in an organic solvent in the presence of a catalyst containing a transition metal and BIBOPs. The preparation method of the present invention uses a small amount of a selected asymmetric catalyst, and has a simple operation, mild reaction conditions, a high yield, a high stereoselectivity, and better industrial application and economic values.

Abstract: Mechanisms are provided for a user equipment (UE) to determine to use a shared resource such as an antenna to access a land based wireless communication system or a satellite communication system. The UE can provide a first priority indication to indicate whether to access the land based wireless communication system based on one or more wireless link metrics of the land based wireless communication system or one or more application metrics for applications using the land based wireless communication system; and provide a second priority indication to indicate whether to access the satellite wireless communication system based on one or more service metrics provided by the satellite wireless communication system. The UE can determine to use the shared resources to access the land based wireless communication system or the satellite communication system based on the first priority indication and the second priority indication.

Abstract: Aspects of the present disclosure implement techniques that allow a vehicle performing V2X communications to provide more accurate S-RSSI measurements and CBR calculations for use in channel selection and congestion control. Techniques may include measuring a sidelink received signal strength indicator (S-RSSI) for each of a plurality of sub-channels, determining one or more signal impairment adjustment factors based on the S-RSSI for each of the plurality of sub-channels, calculating a channel busy ratio (CBR) for the plurality of sub-channels based on the one or more signal impairment adjustment factors, and initiating communication with at least one of the plurality of sub-channels based on at least the CBR.

Abstract: An electrically controlled pneumatic surge prevention device includes a controller, an air filter, a turbocharger, an intercooler, a throttle valve, air pipes, an electromagnetic valve connected using signals to the controller, and a surge prevention valve connected to the electromagnetic valve. The surge prevention valve is connected to a sixth air pipe connecting the intercooler and the throttle valve via a fourth air pipe. The electromagnetic valve is arranged at a third air pipe, and the surge prevention valve is connected to a second air pipe connecting the air filter and the turbocharger via the third air pipe. Also provided is a control method of an electrically controlled pneumatic surge prevention device.

Abstract: An electrically controlled pneumatic surge prevention device includes a controller, an air filter, a turbocharger, an intercooler, a throttle valve, air pipes, an electromagnetic valve connected using signals to the controller, and a surge prevention valve connected to the electromagnetic valve. The surge prevention valve is connected to a sixth air pipe connecting the intercooler and the throttle valve via a fourth air pipe. The electromagnetic valve is arranged at a third air pipe, and the surge prevention valve is connected to a second air pipe connecting the air filter and the turbocharger via the third air pipe. Also provided is a control method of an electrically controlled pneumatic surge prevention device.

Abstract: Aspects of the present disclosure implement techniques that allow a vehicle performing V2X communications to provide more accurate S-RSSI measurements and CBR calculations for use in channel selection and congestion control. Techniques may include measuring a sidelink received signal strength indicator (S-RSSI) for each of a plurality of sub-channels, determining one or more signal impairment adjustment factors based on the S-RSSI for each of the plurality of sub-channels, calculating a channel busy ratio (CBR) for the plurality of sub-channels based on the one or more signal impairment adjustment factors, and initiating communication with at least one of the plurality of sub-channels based on at least the CBR.

Abstract: The present invention provides N6-substituted adenosine derivatives and N6-substituted adenine derivatives, manufacturing methods thereof, a pharmaceutical composition comprising the said compounds above, and uses of these compounds in manufacturing medicaments and health-care products for treating insomnia, convulsion, epilepsy, and Parkinson's diseases, and preventing and treating dementia.

Abstract: The present invention provides N6-substituted adenosine derivatives and N6-substituted adenine derivatives, manufacturing methods thereof, a pharmaceutical composition comprising the said compounds above, and uses of these compounds in manufacturing medicaments and health-care products for treating insomnia, convulsion, epilepsy, and Parkinson's diseases, and preventing and treating dementia.