Abstract: Provided is a series of homologous small molecule immune agonists and novel bifunctional immune targeting compounds having targeting and immune activation functions, which are obtained by coupling the small molecule immune agonists to targeting drugs. The resulting immune targeting compounds are beneficial for enhancing immune activation effects, and anti-tumor and other disease fighting effects of the targeting drug. The enhanced effect is produced from a synergy of immunological anti-tumor factors (such as IFN-?) and inhibition at pathogenic targeting sites.

Abstract: A method for estimating a remaining range of a vehicle battery charge includes identifying at least one route characteristic of a portion of a selected route, determining a vehicle energy consumption profile for a vehicle, and determining a current state of charge of a vehicle battery of the vehicle. The method also includes determining, for the selected route, a route energy consumption profile and calculating an estimated remaining charge for the vehicle battery at an end of the selected route based on the state of charge of the vehicle battery and the route energy consumption profile. The method also includes, in response to a determination that the estimated remaining charge is less than a lower limit of the vehicle battery charge range, determining a target vehicle speed profile based on the at least one route characteristic, the vehicle energy consumption profile, and the state of charge of the vehicle battery.

Abstract: A process and system for creating a lithium ion anolyte from lithium alloys. Metal and lithium alloys are processed to remove the metal with lithium from the alloy remaining. A lithium ion anolyte formed may be used in a process to form lithium metal. Alternatively, a process and system for recovering lithium from sources such as lithium alloys and lithium metal oxides and other feedstock such as recycled batteries into a thin lithium metal film via electrodeposition in an organic electrolyte contacting both anode (holder for lithium source) and cathode (substrate for lithium deposition) in a single-compartment electrolysis cell.

Abstract: A method for controller vehicle propulsion. The method includes identifying at least one route characteristic of a portion of a most probable path, determining a vehicle energy consumption profile for a vehicle based on at least historical data indicating energy consumption of the vehicle for at least a portion of a route previously traversed by the vehicle having at least one route characteristic corresponding to the at least one route characteristic of the portion of the most probable path, and determining, for the most probable path, a route energy consumption profile based on the at least one route characteristic of the portion of the most probable path and the vehicle energy consumption profile. The method also includes determining a target vehicle speed profile based on the at least one route characteristic and the vehicle energy consumption profile and selectively controlling vehicle propulsion based on the target vehicle speed profile.

Abstract: A semiconductor integrated circuit design method and apparatus, and relates to the technical field of semiconductors are provided. The semiconductor integrated circuit design method includes: determining, based on an original layout, an original length of an end of a gate structure extending out of an active region in which the gate structure is located; redetermining, based on a preset rule and the original length, a correction length of the end of the gate structure extending out of the active region in which the gate structure is located; and integrating the original layout and the correction lengths, and forming an updated layout.

Abstract: A lithium ion conducting membrane and methods of making the same. The membrane includes a polymeric matrix and a plurality of ion-conducting particles disposed within the polymeric matrix. An inorganic coating deposited in the polymeric matrix.

Abstract: A method for estimating a remaining range of a vehicle battery charge includes identifying at least one route characteristic of a portion of a selected route, determining a vehicle energy consumption profile for a vehicle, and determining a current state of charge of a vehicle battery of the vehicle. The method also includes determining, for the selected route, a route energy consumption profile and calculating an estimated remaining charge for the vehicle battery at an end of the selected route based on the state of charge of the vehicle battery and the route energy consumption profile. The method also includes, in response to a determination that the estimated remaining charge is less than a lower limit of the vehicle battery charge range, determining a target vehicle speed profile based on the at least one route characteristic, the vehicle energy consumption profile, and the state of charge of the vehicle battery.

Abstract: A method for controlling vehicle propulsion may include identifying at least one route characteristic of a portion of a route being traversed by a vehicle and determining a profile for a target vehicle speed based on the at least one route characteristic and a vehicle energy consumption profile. The method may also include, in response to detecting a lead vehicle, determining a vehicle speed of the lead vehicle and determining whether to avoid triggering initiation of the vehicle follow mode by the vehicle propulsion controller based on (i) a distance between the vehicle and a triggering threshold and (ii) the vehicle speed of the vehicle. The method may also include, in response to not triggering vehicle follow mode, determining, based on the vehicle speed of the lead vehicle and the profile for the target vehicle speed, a traveling distance between the vehicle and a trigger threshold.

Abstract: The present invention relates generally to the field of anti-cancer therapy, in particular to the use of adoptive T cell transfer therapy for treating cancer, in particular sold tumors. More specifically, the present invention relates to immune cells comprising one or more recombinant constructs, wherein at least one recombinant construct encodes an interleukin-10, a fragment or a variant thereof.

Abstract: A layout method for an integrated circuit includes the following steps: providing a layout, the layout including a first element region and a second element region, a spacing region being provided between the first element region and the second element region; and detecting whether a width of the spacing region is less than a preset width, and if yes, marking at least one of the first element region, the second element region and the spacing region, the preset width being a minimum width meeting a requirement, wherein the requirement is to fill the spacing region with at least one dummy pattern. A layout apparatus employing the layout method for the integrated circuit can quickly and accurately position a poorly-placed element region in the layout, improve the layout efficiency and layout precision of the integrated circuit, and lay a foundation for improving photolithography quality.

Abstract: Embodiments of the present disclosure relate to a video processing method and apparatus, a device, and a medium. The method includes: obtaining a reference editing operation sequence specified by a user, where the reference editing operation sequence includes at least one reference editing operation arranged in a sequential order of operations; and providing operation prompts according to the sequential order of the reference editing operations, to direct the user to perform the reference editing operations on a target video step by step, where each reference editing operation in the reference editing operation sequence has a corresponding operation prompt.

Abstract: A method for controlling vehicle propulsion may include identifying at least one route characteristic of a portion of a route being traversed by a vehicle and determining a profile for a target vehicle speed based on the at least one route characteristic and a vehicle energy consumption profile. The method may also include, in response to detecting a lead vehicle, determining a vehicle speed of the lead vehicle and determining whether to avoid triggering initiation of the vehicle follow mode by the vehicle propulsion controller based on (i) a distance between the vehicle and a triggering threshold and (ii) the vehicle speed of the vehicle. The method may also include, in response to not triggering vehicle follow mode, determining, based on the vehicle speed of the lead vehicle and the profile for the target vehicle speed, a traveling distance between the vehicle and a trigger threshold.

Abstract: A method of manufacturing a hollow fiber carbon membrane, the method includes heating a polymeric precursor to a pyrolysis temperature that is greater than or equal to 900° C. and less than or equal to 1200° C., and pyrolyzing the polymeric precursor at the pyrolysis temperature in a pyrolysis atmosphere that comprises oxygen in an amount that is greater than 0 ppm and less than 200 ppm.

Abstract: A method for estimating a remaining range of a vehicle battery charge includes identifying at least one route characteristic of a portion of a selected route, determining a vehicle energy consumption profile for a vehicle and determining a current state of charge of a vehicle battery of the vehicle. The method also includes determining, for the selected route, a route energy consumption profile and calculating an estimated remaining charge for the vehicle battery at an end of the selected route based on the state of charge of the vehicle battery and the route energy consumption profile. The method also includes determining whether the estimated remaining charge for the vehicle battery is within a vehicle battery charge range and, in response to a determination that the estimated remaining charge is within the vehicle battery charge range, generating a first indication; and providing the first indication.

Abstract: A numerical control process design and optimization method based on machining knowledge includes: constructing a machining knowledge data model by taking a machining feature as a carrier, performing ordered integration on various stages of programming, post-processing, cutting simulation, machining process monitoring and inspection, and machining result measurement, determining various storage data types, and storing data in each stage. By means of the numerical control process design and optimization method, data stream during the whole flow of product machining are connected; effective accumulation of knowledge in a full cycle of product machining is realized; a numerical control process basic data model is constructed by means of establishing an association relationship between machining knowledge and a feature of a part.

Abstract: A method for providing a vehicle energy optimization rationality check includes identifying at least one route characteristic of a portion of a route being traversed by a vehicle, determining a vehicle energy consumption profile for the vehicle, determining a profile for a target vehicle speed based on the at least one route characteristic and the vehicle energy consumption profile, determining, based on at least the at least one route characteristic, an alternative target vehicle speed, and, in response to a difference between the target vehicle speed and the alternative vehicle speed being greater than a threshold, performing a default action.

Abstract: A memory apparatus and a data rearrangement method for computing in memory (CIM) are provided. The method includes determining whether first sequence data has two target bits that are both of a first value, inserting a non-target bit of a second value between the two target bits that are both of the first value and adjacent to each other to generate second sequence data, and receiving the second sequence data through memory cells in a memory to perform a multiply-accumulate (MAC) operation on the second sequence data. Each bit in the first sequence data is the first value or the second value. One of the two target bits is located adjacent to the other one of the two target bits in the first sequence data. The two target bits and the non-target bit are located in the first sequence data. Accordingly, the error rate is decreased.

Abstract: A process for producing a deformed nonwoven is described. The process includes the steps of: adjusting a water content of a nonwoven such that the nonwoven has at least one area having a water content of at least about 12% by weight of the nonwoven in the area, and subjecting the nonwoven to a mechanical deformation process. The deformation process is a mechanical deformation of the nonwoven and dewatering of the nonwoven to obtain a deformed nonwoven.

Abstract: A stem removal device for a cigarette making process is disclosed, including a feeding unit (N1), a flexible air sorting unit (N2), a pure tobacco collection unit (N3), a tobacco conveying unit (N4), a coarse stem removal unit (N5) and a fine stem removal unit (N6). A method for removing the stems during the cigarette making process using the stem removal device is also disclosed.