Patents by Inventor Li-Wu Chiang

Li-Wu Chiang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOUND FOR ACTIVATING NATURAL KILLER T CELLS AND PREPARING METHOD THEREOF
    Publication number: 20130217639
    Abstract: The present invention provides a compound selected from compound of formula (I), pharmaceutically acceptable salts of compound of formula (I), and pharmaceutically acceptable prodrugs of compound of formula (I), and a composition comprising the compound of the above and a pharmaceutically acceptable excipient. The present invention also provides a method for preparing a compound that activates natural killer T cells.
    Type: Application
    Filed: February 22, 2012
    Publication date: August 22, 2013
    Applicant: NATIONAL TSING HUA UNIVERSITY
    Inventors: Chung-Shan Yu, Li-Wu Chiang, Kai-Hsiang Chang, Kuo-Yen Liao, Wen-Chin Su, Yin-Cheng Huang
  • Construction and screening of solution-phase derived library of fenbufen and ethacrynic acid
    Patent number: 8093427
    Abstract: A process for synthesizing and screening solution phase derived libraries of fenbufen and ethacrynic acid is provided in the present invention. Compounds in the present invention having cytotoxicities are useful for a variety of therapeutic applications.
    Type: Grant
    Filed: June 9, 2010
    Date of Patent: January 10, 2012
    Assignee: National Tsing Hua University
    Inventors: Chung-Shan Yu, Yuan-Hsiao Su, Li-Wu Chiang, Chia-Rong Chen, Shao-Wei Chen, Chia-Wen Huang, Ho-Lien Huang, Yin-Cheng Huang
  • CONSTRUCTION AND SCREENING OF SOLUTION-PHASE DERIVED LIBRARY OF FENBUFEN AND ETHACRYNIC ACID
    Publication number: 20110306668
    Abstract: A process for synthesizing and screening solution phase derived libraries of fenbufen and ethacrynic acid is provided in the present invention. Compounds in the present invention having cytotoxicities are useful for a variety of therapeutic applications.
    Type: Application
    Filed: June 9, 2010
    Publication date: December 15, 2011
    Applicant: NATIONAL TSING HUA UNIVERSITY
    Inventors: Chung-Shan Yu, Yuan-Hsiao Su, Li-Wu Chiang, Chia-Rong Chen, Shao-Wei Chen, Chia-Wen Huang, Ho-Lien Huang, Yin-Cheng Huang
  • AMIDE-BASED SOLUTION-PHASE DERIVED LIBRARY AND METHOD FOR SCREENING THEREOF
    Publication number: 20110245088
    Abstract: An amide-based library is disclosed in the invention which is prepared via amide bond formation coupling an amine with a carboxylic acid. Also, a method using said library for screening a drug candidate is provided in the present invention. Compounds in the present invention having cytotoxicities are useful for a variety of therapeutic applications.
    Type: Application
    Filed: April 5, 2010
    Publication date: October 6, 2011
    Applicant: NATIONAL TSING HUA UNIVERSITY
    Inventors: Chung-Shan Yu, Li-Wu Chiang, Shao-Wei Chen, Chia-Wen Huang, Ho-Lien Huang, Kai Pei
  • Method and precursor for production of no-carrier-added N-(4-[18F] fluorobutyl)-Ethacrynic amide
    Publication number: 20110077430
    Abstract: The present invention is related to a precursor for no-carrier-added fluorine-18 labeled ethacrynic acid, N-(4-[18F]fluorobutyl)-Ethacrynic amide([18F]FBuEA) and the preparation method for HPLC non-radioactive standards. Its chemical structure is shown in the following: In the precursor, R1 represents a protective group for the amide functional group; R2 represents leaving group; or R1 represents carboxyl group, R2 represents p-tosyloxy, methane sulfonyloxy group or trifluoromethane sulfonyloxy group or bromine (Br). For the HPLC non-radioactive standards, R1 represents a protective group for the amide functional group and hydrogen, R2 represents fluorine.
    Type: Application
    Filed: September 30, 2009
    Publication date: March 31, 2011
    Inventors: Chung-Shan Yu, Li-Wu Chiang, Hao-Lien Huang, Yu-Hsuan Ku, Chia-Jung Chen, Shao Wei Chen, Yean-Hung Tu, Mao-Hsung Chang, Jenn-Tzong Chen, Wuu-Jyn Lin