Abstract: An apparatus including a battery cell includes an electrode stack. The electrode stack includes an anode electrode, a cathode electrode, and a separator disposed between the anode electrode and the cathode electrode. The apparatus further includes an enclosure configured for encasing and mechanically protecting the electrode stack. The apparatus further includes an electrolyte. The apparatus further includes a thermally conductive and electrically insulated inert fill material located between the electrode stack and the enclosure configured for providing a thermally conductive connection between the electrode stack and the enclosure.

Abstract: The present application provides an audio and video playing system, a playing method and a playing device. The system comprises: a display device; a directional sound output module configured to output a directional sound signal; a tracking element configured to monitor a target visual area and to monitor the target display area on the display screen; and a processor, connected with the directional sound output module and the tracking element respectively, and configured to acquire a first audio and video data to be output in the target display area, display image information of the first audio and video data in the target display area, and output sound information of the first audio and video data to the directional sound output module such that the directional sound output module output a directional sound signal towards the target visual area.

Abstract: A rotary-transmission-target microfocus X-ray source and an X-ray generation method based on the rotary-transmission-target microfocus X-ray source are provided. The X-ray source comprises a chamber, and an electron beam system is installed in the chamber. The electron beam system is arranged on a same side as an anode target rotating shaft. A motor in a rotary anode target system drives an anode target to rotate through a bevel gear transmission device. The microstructure of a target is designed. An electron beam emitted by the electron beam system vertically bombards the metal target of the rotating anode target. A cooling system is configured to cool the anode target.

Abstract: A rotary-transmission-target microfocus X-ray source and an X-ray generation method based on the rotary-transmission-target microfocus X-ray source are provided. The X-ray source comprises a chamber, and an electron beam system is installed in the chamber. The electron beam system is arranged on a same side as an anode target rotating shaft. A motor in a rotary anode target system drives an anode target to rotate through a bevel gear transmission device. The microstructure of a target is designed. An electron beam emitted by the electron beam system vertically bombards the metal target of the rotating anode target. A cooling system is configured to cool the anode target.

Abstract: The present invention relates to a method for treating inflammatory bowel disease (IBD) in a patient, the method comprising administering to the patient an anti-TNF-like ligand 1A (TL1A) antibody in an induction dosing regimen sufficient to improve signs and symptoms of IBD by at least 12 weeks after the start of treatment with the anti-TL1A antibody, said induction dosing regimen comprising a plurality of individual induction doses, wherein the method further comprises administering to the patient a subsequent maintenance dosing regimen after completion of the induction dosing regimen, said maintenance dosing regimen comprising a plurality of individual maintenance doses separated from each other by at least 2 weeks.

Abstract: Provided herein are compounds, compositions, and methods for treating cancer in a subject in need thereof.

Abstract: Provided herein are compounds, compositions, and methods for treating cancer in a subject in need thereof.

Abstract: Provided herein are compounds, compositions, and methods for treating cancer in a subject in need thereof; wherein the compound has formula (I): or an N-oxide thereof, or a pharmaceutically acceptable salt of each thereof, or a pharmaceutically acceptable solvate of each of the foregoing, wherein R1 is H or has a structure of: R3 is H, an optionally substituted C1-C8 alkyl, an optionally substituted 3-10 membered cycloalkyl, an optionally substituted 3-10 membered heterocyclyl, an optionally substituted 6-10 membered aryl, or an optionally substituted 5-10 membered heteroaryl; R5 is H or has a structure of: and R11 and R12 independently is an optionally substituted C1-C8 alkyl.

Abstract: Provided herein are compounds, compositions, and methods for treating cancer in a subject in need thereof.

Abstract: Provided herein are compounds, compositions, and methods for treating cancer in a subject in need thereof.

Abstract: Camptothecin-based compounds are useful for treating a neoplasm in mammalian subjects by administering such compound to the subjects in combination with radiotherapy, i.e., the treatment of tumors with radioactive substances or radiation from a source external to the subject. Camptothecin-based compounds are modified by positioning at least one electron-affinic group around the camptothecin structure to enhance their value in combination with radiotherapy. New Camptothecin-based compounds are disclosed that are useful for treating cancer by administering the novel compounds alone or in combination with radiotherapy.

Abstract: Camptothecin-based compounds are useful for treating a neoplasm in mammalian subjects by administering such compound to the subjects in combination with radiotherapy, i.e., the treatment of tumors with radioactive substances or radiation from a source external to the subject. Camptothecin-based compounds are modified by positioning at least one electron-affinic group around the camptothecin structure to enhance their value in combination with radiotherapy. New Camptothecin-based compounds are disclosed that are useful for treating cancer by administering the novel compounds alone or in combination with radiotherapy.

Abstract: 4-O esters of podophyllotoxin and 4?-demethylepipodophyllotoxin are provided. The compounds are 4-O esters of an alkanoic acid or substituted alkanoic acid and podophyllotoxin and 4?-demethylepipodophyllotoxin. The compounds are useful for treating cancer.

Abstract: Camptothecin-based compounds are useful for treating a neoplasm in mammalian subjects by administering such compound to the subjects in combination with radiotherapy, i.e., the treatment of tumors with radioactive substances or radiation from a source external to the subject. Camptothecin-based compounds are modified by positioning at least one electron-affinic group around the camptothecin structure to enhance their value in combination with radiotherapy. New Camptothecin-based compounds are disclosed that are useful for treating cancer by administering the novel compounds alone or in combination with radiotherapy.

Abstract: Camptothecin-based compounds are useful for treating a neoplasm in mammalian subjects by administering such compound to the subjects in combination with radiotherapy, i.e., the treatment of tumors with radioactive substances or radiation from a source external to the subject. Camptothecin-based compounds are modified by positioning at least one electron-affinic group around the camptothecin structure to enhance their value in combination with radiotherapy. New Camptothecin-based compounds are disclosed that are useful for treating cancer by administering the novel compounds alone or in combination with radiotherapy.

Abstract: 4-O esters of podophyllotoxin and 4?-demethylepipodophyllotoxin are provided. The compounds are 4-O esters of an alkanoic acid or substituted alkanoic acid and podophyllotoxin and 4?-demethylepipodophyllotoxin. The compounds are useful for treating cancer.

Abstract: A loop antenna device is disclosed with an increased number of turns, a large opening area, and a high Q value. The loop antenna device includes: a conductor wound spirally on an insulating substrate, wherein the conductor is constituted by a plurality of loops which are connected and each of which has a substantially rectangular shape with predetermined height and width in a cross-sectional view, and with regard to the adjacent loops of which height portions face each other, a height of the one loop is smaller than a height of the other loop, and a width of the other loop is smaller than a width of the one loop.

Abstract: 4-O esters of podophyllotoxin and 4?-demethylepipodophyllotoxin are provided. The compounds are 4-O esters of an alkanoic acid or substituted alkanoic acid and podophyllotoxin and 4?-demethylepipodophyllotoxin. The compounds are useful for treating cancer.

Abstract: The disclosure provides androsterone derivatives. The derivatives of the disclosure are useful in the treatment of androgen- and estrogen-associated diseases and disorders, including breast cancer.

Abstract: Camptothecin-based compounds are useful for treating a neoplasm in mammalian subjects by administering such compound to the subjects in combination with radiotherapy, i.e., the treatment of tumors with radioactive substances or radiation from a source external to the subject. Camptothecin-based compounds are modified by positioning at least one electron-affinic group around the camptothecin structure to enhance their value in combination with radiotherapy. New Camptothecin-based compounds are disclosed that are useful for treating cancer by administering the novel compounds alone or in combination with radiotherapy.