Abstract: The invention relates to Proprotein Convertase Subtilisin Kexin type 9 (PCSK9) antagonists, such as antibodies and fragments, as well as methods, uses and combinations.

Abstract: Some embodiments relate to a roofing structure. The roofing structure comprises a plurality of roofing membranes positioned on a roofing substrate. Each of the plurality of roofing membranes comprises an edge portion that abuts or overlaps with, or is adjacent to, an edge portion of another roofing membrane, so as to define a plurality of seams between adjacent roofing membranes. The roofing structure further comprises a plurality of standing seam structures positioned over the plurality of seams so as to conceal the plurality of seams.

Abstract: Some embodiments of the present disclosure relate to a roofing system. In some embodiments, the roofing system includes a first roofing material, wherein the first roofing material comprises a top surface and a bottom surface. In some embodiments, the top surface of the first roofing material comprises a nail zone with a plurality of fines. In some embodiments, the roofing system includes a second roofing material, wherein the second roofing material comprises a top surface and a bottom surface. In some embodiments, the bottom surface of the second roofing material comprises a plurality of fines. In some embodiments, the roofing system comprises and a patterned adhesive, which directly contacts at least a portion of the plurality of fines in the nail zone and at least a portion of the plurality of fines on the bottom surface of the second roofing material.

Abstract: Provided are methods of reducing the stress of a semiconductor wafer. The method includes exposing depositing an aluminum layer on a top surface of a substrate; and cooling the substrate to a temperature of less than or equal to 20° C., or less than or equal to 10° C., or less than or equal to 0° C., or less than or equal to ?20° C. In some embodiments, the method is conducted within a processing tool, e.g., a cluster tool.

Abstract: Membranes are provided. A membrane comprises a cap layer, a core layer, and a substrate located between the cap layer and the core layer. The cap layer comprises a first cap sublayer and a second cap sublayer, with the second cap sublayer located between the first cap sublayer and the substrate. The first cap sublayer comprises a first thermoplastic polymer, and no greater than 10 parts of a first fire retardant per 100 parts of the first thermoplastic polymer. The second cap sublayer comprises a second thermoplastic polymer, and a second fire retardant, wherein an amount of the second fire retardant in the second cap sublayer is greater than an amount of the first fire retardant in the first cap sublayer. Related systems and methods are also provided.

Abstract: Some embodiments of the present disclosure relate to a roofing system. In some embodiments, the roofing system includes a roofing membrane, which may include a cap, a scrim, and a core. In some embodiments, the roofing system may also include an adhesive film, which may include a first adhesive layer adhered to the roofing membrane, a second adhesive layer configured to adhere the roofing membrane to a roofing substrate, and a barrier layer positioned between the first and second adhesive layers. Methods of manufacturing roofing systems are also disclosed.

Abstract: A method for depositing a film layer on a substrate incorporates ion flux control to alter sputtering atom trajectories. A method may include flowing argon gas around a periphery of the substrate with a surface of the substrate having a plurality of structures with sidewalls and an edge region containing edge structures near the periphery of the substrate, forming a plasma to ionize the argon gas to form Ar+ ion flux to induce sputtering of aluminum to generate aluminum atoms for deposition on the substrate, generating an AC bias on the substrate to increase the Ar+ ion flux density at the edge region of the substrate to alter aluminum atom trajectories striking the edge region, and heating the substrate to increase mobility of the aluminum atoms deposited on the edge structures.

Abstract: Some embodiments of the present disclosure relate to a roofing system. In some embodiments, the roofing system includes a first roofing material, wherein the first roofing material comprises a top surface and a bottom surface. In some embodiments, the top surface of the first roofing material comprises a nail zone with a plurality of fines. In some embodiments, the roofing system includes a second roofing material, wherein the second roofing material comprises a top surface and a bottom surface. In some embodiments, the bottom surface of the second roofing material comprises a plurality of fines. In some embodiments, the roofing system comprises and a patterned adhesive, which directly contacts at least a portion of the plurality of fines in the nail zone and at least a portion of the plurality of fines on the bottom surface of the second roofing material.

Abstract: Some embodiments relate to a roofing membrane. The roofing membrane comprises a scrim. The scrim has a top surface and a bottom surface. The roofing membrane comprises a cap layer on the top surface of the scrim. The cap layer comprises a first non-styrenic polypropylene polymer, a first polypropylene impact copolymer, and a first olefin block copolymer. The roofing membrane comprises a core layer on the bottom surface of the scrim. The core layer comprises a second non-styrenic polypropylene polymer, a second polypropylene impact copolymer, and a second olefin block copolymer. The roofing membrane is configured to prevent migration of at least one oil from a layer to the roofing membrane. Some embodiments relate to a roofing structure comprising the roofing membrane, a method for installing the roofing membrane, and the like.

Abstract: The present invention relates to antibodies that are specific for SARS-CoV-2. The present invention also provides methods of treatment, uses, pharmaceutical compositions and kits comprising the antibodies.

Abstract: Some embodiments of the present disclosure relate to a roofing system. In some embodiments, the roofing system includes a roofing membrane, which may include a cap, a scrim, and a core. In some embodiments, the roofing system may also include an adhesive film, which may include a first adhesive layer adhered to the roofing membrane, a second adhesive layer configured to adhere the roofing membrane to a roofing substrate, and a barrier layer positioned between the first and second adhesive layers. Methods of manufacturing roofing systems are also disclosed.

Abstract: A catalyst, a catalyst synthesis method (10) and a catalytic plastic conversion method (50) are provided. The catalyst includes a single metal oxide on a catalyst support. The catalyst synthesis method (10) includes dissolving (12) a single metal precursor in deionised water to form a precursor-containing solution, mixing (14) a catalyst support into the precursor-containing solution to impregnate the catalyst support with the precursor-containing solution, drying (18) the impregnated catalyst support, and calcining (20) the dried impregnated catalyst support to form a supported single metal oxide catalyst.

Abstract: An imaging device includes an imaging mechanism, a lens assembly having an optical axis and including a transparent lens, and a first moiré lens assembly including a first diffractive lens and a second diffractive lens. The imaging mechanism includes a light emitting element, a light receiving element, and a calculation element. A through hole is defined by the transparent lens. Along the optical axis, a projection of the light receiving element is located within a projection range of the through hole, a projection of the light emitting element is located within a projection range of the transparent lens. The first diffractive lens is fixed in the through hole. The second diffractive lens is fixed between the first diffractive lens and the light receiving element. The transparent lens is configured to drive the first diffractive lens to rotate to adjust a focal length of the first moiré lens assembly.

Abstract: The present invention provides a reduced-height image-capturing module, which includes a lens assembly, an image-sensing chip, a carrier base and a circuit substrate. The carrier base has a base body, two extending plate bodies extending and a base groove recessed. A lower portion of the base body enters a through opening of the circuit substrate, and the two extending plate bodies cross over the through opening of the circuit substrate and are disposed on an upper surface of the circuit substrate. The image-sensing chip is disposed on a recessed bottom surface of the base groove which is not at the same level as the upper surface of the circuit substrate, so that the recessed bottom surface is lower than the upper surface of the circuit substrate. The lens assembly is disposed on the upper portion of the base body and corresponds to the image-sensing chip.

Abstract: Some embodiments relate to a roofing membrane. The roofing membrane comprises a scrim. The scrim has a top surface and a bottom surface. The roofing membrane comprises a cap layer on the top surface of the scrim. The cap layer comprises a first non-styrenic polypropylene polymer, a first polypropylene impact copolymer, and a first olefin block copolymer. The roofing membrane comprises a core layer on the bottom surface of the scrim. The core layer comprises a second non-styrenic polypropylene polymer, a second polypropylene impact copolymer, and a second olefin block copolymer. The roofing membrane is configured to prevent migration of at least one oil from a layer to the roofing membrane. Some embodiments relate to a roofing structure comprising the roofing membrane, a method for installing the roofing membrane, and the like.

Abstract: Some embodiments of the present disclosure relate to a roofing system. In some embodiments, the roofing system includes a first roofing material, wherein the first roofing material comprises a top surface and a bottom surface. In some embodiments, the top surface of the first roofing material comprises a nail zone with a plurality of fines. In some embodiments, the roofing system includes a second roofing material, wherein the second roofing material comprises a top surface and a bottom surface. In some embodiments, the bottom surface of the second roofing material comprises a plurality of fines. In some embodiments, the roofing system comprises and a patterned adhesive, which directly contacts at least a portion of the plurality of fines in the nail zone and at least a portion of the plurality of fines on the bottom surface of the second roofing material.

Abstract: Embodiments described herein relate to managing wireless connections within a spatially-dense setting like a passenger vehicle, thereby improving quality and reliability of individual wireless connections. An example method includes detecting a connection request from a passenger device requesting a wireless connection with a seatback device in a first in-vehicle location. The method includes defining a density zone that includes other in-vehicle locations surrounding the first in-vehicle location. The density zone localizes an area within which other wireless connections may be disruptive to the wireless connection. The method includes determining, via a token server that stores connection tokens that each describe an existing connection, a number of particular tokens that describe existing connections located within the density zone.

Abstract: The present disclosure provides a semiconductor structure with having a source/drain feature with a central cavity, and a source/drain contact feature formed in central cavity of the source/drain region, wherein the source/drain contact feature is nearly wrapped around by the source/drain region. The source/drain contact feature may extend to a lower most of a plurality semiconductor layers.

Abstract: Some embodiments of the present disclosure relate to a roofing system. In some embodiments, the roofing system includes a first roofing material, wherein the first roofing material comprises a top surface and a bottom surface. In some embodiments, the top surface of the first roofing material comprises a nail zone with a plurality of fines. In some embodiments, the roofing system includes a second roofing material, wherein the second roofing material comprises a top surface and a bottom surface. In some embodiments, the bottom surface of the second roofing material comprises a plurality of fines. In some embodiments, the roofing system comprises and a patterned adhesive, which directly contacts at least a portion of the plurality of fines in the nail zone and at least a portion of the plurality of fines on the bottom surface of the second roofing material.

Abstract: Some embodiments of the present disclosure relate to a roofing system. In some embodiments, the roofing system includes a roofing membrane, which may include a cap, a scrim, and a core. In some embodiments, the roofing system may also include an adhesive film, which may include a first adhesive layer adhered to the roofing membrane, a second adhesive layer configured to adhere the roofing membrane to a roofing substrate, and a barrier layer positioned between the first and second adhesive layers. Methods of manufacturing roofing systems are also disclosed.