Abstract: The present invention relates to the field of biomedicine, particularly to double-stranded RNA molecules targeting CKIP-1 and uses thereof, particularly to use of the double-stranded RNA molecules for the treatment of inflammatory diseases such as arthritis, particularly rheumatoid arthritis.

Abstract: Provided are use of a rare earth amino acid complex, a polylactic acid composition and a preparation method thereof. The rare earth amino acid complex is formed by complexing a rare earth metal ion with an amino acid; a rare earth element corresponding to the rare earth metal ion is one or more selected from the group consisting of lanthanum, cerium and samarium; and the amino acid is at least one selected from the group consisting of proline, L-phenylalanine, tyrosine and tryptophan.

Abstract: A P2X3 and/or P2X2/3 receptor antagonist of formula (I), a pharmaceutical composition comprising the same, and a use thereof in preparing a drug for preventing or treating a disease mediated by the P2X3 and/or P2X2/3 receptor antagonist.

Abstract: Methods for forming elastomeric polyurethane articles are provided in which an isocyanate component including an isocyanate prepolymer is mixed with an isocyanate-reactive component having a viscosity ranging from 50,000 to 200,000 centipoise as measured by ASTM standard D2196, and wherein is applied as one or more layers onto a surface of a carrier substrate at an application rate ranging from 0.5 to 20 g/sec, with each one of said applied one or more layers independently having a thickness ranging from 0.2 and 10 millimeters and having a total thickness ranging from ranging from 0.2 to 60 millimeters. The applied layers are cured in the absence of added heat via an exothermic reaction to form the elastomeric polyurethane article having an abrasion resistance ranging from 20 to 250 mm3, a hardness ranging from 60 Asker C to 90 Asker C, and a density ranging from 330 and 1000 kg/m3.

Abstract: Disclosed herein are viscoelastic elastomeric polyurethane foams, a process for preparing them and a method of using them in making shaped articles. Further disclosed herein are of viscoelastic elastomeric polyurethane foams having improved, unique impact absorption performance.

Abstract: This application provides a display panel and a terminal device. The display panel is provided with an effective display region, a hole-punch region located in the effective display region, and a border region surrounding the hole-punch region. The effective display region is provided with a plurality of first traces extending in a first direction, and second traces extending in a second direction, where the first direction is perpendicular to the second direction. In at least a portion of the first traces whose extension directions pass through the hole-punch region, portions of each first trace respectively arranged on two sides of the hole-punch region are connected by one of first windings, to ensure that the portions of the first trace respectively arranged on the two sides of the hole-punch region are connected, and at least a portion of the first windings are located in the effective display region.

Abstract: Disclosed is a method for evaluating cooking quality that includes: in response to receiving evaluation information of a food sent by a terminal, retrieving an assessment result corresponding to the food, the assessment result being an assessment result of the cooking quality of a cooking appliance; and determining an evaluation result of the cooking quality of the cooking appliance based on the assessment result, the evaluation information, and a preset evaluation rule. Also disclosed is a device for evaluating cooking quality. With this disclosure, both the assessment result and the evaluation information are weighted in computing the evaluation result of the cooking quality of the cooking appliance. Such an evaluation result not only reflects users' subjective evaluation of the cooking quality, but it also reflects an objective and tenable evaluation of the cooking quality, making the evaluation of the cooking quality more reasonable.

Abstract: The present disclosure relates to spray polyether and polyester polyurethane elastomeric articles and associated methods of producing such elastomer articles. More specifically, the invention provides spray polyester polyurethane elastomer articles that exhibit excellent tensile and tear strength, superior elongation performance and improved abrasion resistance performance with tunable tensile modulus.

Abstract: A superhydrophobic coating having a three-dimensional porous nanocomposite structure, includes: a constructing unit and a bonding unit; the constructing unit comprises inorganic hydrophobic nanoparticles, the bonding unit comprises hydrophobic polymer nanomicrospheres, and the inorganic hydrophobic nanoparticles and the hydrophobic polymer nanomicrospheres are interconnected to form uniform pores. A method for preparation of the superhydrophobic coating includes: mixing the inorganic hydrophobic nanoparticles with the hydrophobic polymer nanomicrospheres in a dispersant to form a coating solution; and coating the coating solution on the surface of a substrate using a dip coating, roll coating or spray coating process, and drying to form the superhydrophobic coating of a three-dimensional porous nanocomposite structure.

Abstract: The present disclosure provides a cooking appliance control method, a control device, and a cooking appliance. The cooking appliance acquires cooking effect evaluation information of a cooking appliance provided by a user. The cooking effect evaluation information comprises a plurality of evaluation dimensions for evaluating cooking effects of the cooking appliance and scores of the plurality of evaluation dimensions. The cooking appliance adjusts control parameters of the cooking appliance according to the cooking effect evaluation information, so as to control the cooking of the cooking appliance according to the adjusted control parameters. By adjusting the control parameters of the cooking appliance according to the cooking effect evaluation information, the cooking appliance ensures that the final cooking effect satisfy the requirements of the user and improves the use experience of the user.

Abstract: Methods for forming elastomeric polyurethane articles are provided in which an isocyanate component including an isocyanate pre-polymer is mixed with an isocyanate-reactive component having a viscosity ranging from 50,000 to 200,000 centipoise as measured by ASTM standard D2196, and wherein is applied as one or more layers onto a surface of a carrier substrate at an application rate ranging from 0.5 to 20 g/sec, with each one of said applied one or more layers independently having a thickness ranging from 0.2 and 10 millimeters and having a total thickness ranging from ranging from 0.2 to 60 millimeters. The applied layers are cured in the absence of added heat via an exothermic reaction to form the elastomeric polyurethane article having an abrasion resistance ranging from 20 to 250 mm3, a hardness ranging from 60 Asker C to 90 Asker C, and a density ranging from 330 and 1000 kg/m3.

Abstract: The present invention discloses a thermosensitive nanocapsule and a preparing method thereof. The thermosensitive nanocapsule includes core materials and wall materials. The preparing method includes: first, making water phase and oil phase respectively, forming microemulsion by means of high speed shearing after mixing, and forming nanoemulsion via ultrasonic treatment or high pressure homogenization; then adding nitrogen to the emulsion and carrying out the reaction under a temperature of 40-80° C. for 3-4 hrs in the nitrogen atmosphere; finally obtaining the thermosensitive nanocapsule with an embedding rate of 90-94%, a particle size of less than 150 nm and a dimension polydispersity index of 0.09-0.17. In present invention, the monomer that forms the wall material of the nanocapsules is made from common biological materials, and has a good biocompatibility. The wall material has a temperature sensitivity, and can control the delayed release of core material by adjusting temperature.

Abstract: A sample adding system for automatically adding a sputum digestion liquid includes a weighing device provided with a weight sensor and a sample adding device. A liquid inlet of a sample adding tube goes deep into the sputum digestion liquid reagent bottle, and a liquid outlet of the sample adding tube extends to a position above the weighing device. A sample adding needle is connected to the liquid outlet of the sample adding tube. The sample adding tube is equipped with a quantitative sample adding pump. A signal output end of the weight sensor is electrically connected to a signal input end of a single-chip microcomputer, and a control output end of the single-chip microcomputer is electrically connected to a control input end of the quantitative sample adding pump.

Abstract: The present invention discloses a thermosensitive nanocapsule and a preparing method thereof. The thermosensitive nanocapsule includes core materials and wall materials. The preparing method includes: first, making water phase and oil phase respectively, forming microemulsion by means of high speed shearing after mixing, and forming nanoemulsion via ultrasonic treatment or high pressure homogenization; then adding nitrogen to the emulsion and carrying out the reaction under a temperature of 40-80° C. for 3-4 hrs in the nitrogen atmosphere; finally obtaining the thermosensitive nanocapsule with an embedding rate of 90-94%, a particle size of less than 150 nm and a dimension polydispersity index of 0.09-0.17. In present invention, the monomer that forms the wall material of the nanocapsules is made from common biological materials, and has a good biocompatibility. The wall material has a temperature sensitivity, and can control the delayed release of core material by adjusting temperature.

Abstract: The present disclosure provides a cooking appliance control method, a control device, and a cooking appliance. The cooking appliance acquires cooking effect evaluation information of a cooking appliance provided by a user. The cooking effect evaluation information comprises a plurality of evaluation dimensions for evaluating cooking effects of the cooking appliance and scores of the plurality of evaluation dimensions. The cooking appliance adjusts control parameters of the cooking appliance according to the cooking effect evaluation information, so as to control the cooking of the cooking appliance according to the adjusted control parameters. By adjusting the control parameters of the cooking appliance according to the cooking effect evaluation information, the cooking appliance ensures that the final cooking effect satisfy the requirements of the user and improves the use experience of the user.

Abstract: The inhibitory oligonucleotides (ODNs) strongly block NF-?B activation induced by TLR9 agonists and TLR7 agonists. The production of proinflammatory cytokines, such as interleukin-6 and tumor necrosis factor alpha, is inhibited by the inhibitory-ODNs. Interferon production from human PBMC induced by TLR9 agonist is prevented by the inhibitory-ODNs. These ODNs can be used as a remedy for the treatment of immune-mediated disorders such as rheumatoid arthritis, systemic lupus erythematosus (SLE), sepsis, multiple organ dysfunction syndromes.

Abstract: Disclosed is a method for evaluating cooking quality that includes: in response to receiving evaluation information of a food sent by a terminal, retrieving an assessment result corresponding to the food, the assessment result being an assessment result of the cooking quality of a cooking appliance; and determining an evaluation result of the cooking quality of the cooking appliance based on the assessment result, the evaluation information, and a preset evaluation rule. Also disclosed is a device for evaluating cooking quality. With this disclosure, both the assessment result and the evaluation information are weighted in computing the evaluation result of the cooking quality of the cooking appliance. Such an evaluation result not only reflects users' subjective evaluation of the cooking quality, but it also reflects an objective and tenable evaluation of the cooking quality, making the evaluation of the cooking quality more reasonable.

Abstract: A polyurethane foam having an initial UL 94 vertical flame classification of V-0 and maintaining a UL 94 vertical flame classification of V-0 after one week of heat aging at 150° C. is formed as the reaction product of an isocyanate component and an isocyanate-reactive component in the presence of a blowing agent. The isocyanate component includes an isocyanate-containing compound and a non-reactive phosphorous compound that is present in an amount ranging from 1 to 20 weight percent based on the total weight of the polyurethane foam. The isocyanate-reactive component includes a polyether polyol and expandable graphite that is present in an amount ranging from 3 to 30 weight percent based on the total weight of the polyurethane foam.

Abstract: The inhibitory oligonucleotides (ODNs) strongly block NF-?B activation induced by TLR9 agonists and TLR7 agonists. The production of proinflammatory cytokines, such as interleukin-6 and tumor necrosis factor alpha, is inhibited by the inhibitory-ODNs. Interferon production from human PBMC induced by TLR9 agonist is prevented by the inhibitory-ODNs. These ODNs can be used as a remedy for the treatment of immune-mediated disorders such as rheumatoid arthritis, systemic lupus erythematosus (SLE), sepsis, multiple organ dysfunction syndromes.

Abstract: The inhibitory oligonucleotides (ODNs) which strongly block NF-?B activation induced by TLR9 agonists and TLR7 agonists are provided. The production of proinflammatory cytokines, such as interleukin-6 and tumor necrosis factor alpha, is inhibited by the inhibitory-ODNs. Interferon production from human PBMC induced by TLR9 agonist is prevented by the inhibitory-ODNs. These ODNs can be used as a remedy for the treatment of immune-mediated disorders such as rheumatoid arthritis, systemic lupus erythematosus (SLE), sepsis, multiple organ dysfunction syndromes.