Abstract: Devices, systems and methods for coefficient coding in transform skip mode are described. An exemplary method for visual media processing includes: for encoding a current video block in a video region of a visual media data into a bitstream representation of the visual media data, identifying usage of a coding mode and/or an intra prediction mode and/or a set of allowable intra prediction modes; and upon identifying the usage, making a decision of whether to include or exclude, in the bitstream representation, a syntax element indicative of selectively applying a transform skip mode to the current video block, wherein, in the transform skip mode, a residual of a prediction error between the current video block and a reference video block is represented in the bitstream representation of the visual media data without applying a transformation.

Abstract: A method of processing video data is described. The method includes performing a conversion between a current video block of a video and a bitstream of the video. A geometric partitioning mode index for the current video block is coded in the bitstream and a binarization of the geometric partitioning mode index is performed according to a rule. The geometric partitioning mode index specifies a geometric splitting shape of a geometric partitioning mode applied to the current video block. The rule specifies that the geometric partitioning mode index is coded with a fixed-length binarization.

Abstract: An example method of video processing includes making a determination, for a conversion between a current video block of a video and a bitstream representation of the video, whether a cross-component adaptive loop filtering tool is enabled for the current video block based on a color property of the video. The method also includes performing the conversion according to the determination.

Abstract: A video coding or decoding method includes using history-based motion vector prediction (HMVP) for conversion between multiple video blocks including a current block of video and a bitstream representation of the multiple video blocks such that for a uni-predicted block that for which a single reference picture is used for motion compensation, refraining from updating a look-up table for HMVP candidates for the uni-predicted block. The video coding or decoding method further includes performing the conversion using look-up tables for the multiple video blocks.

Abstract: The disclosure provides a glitch removal circuit with low latency. The glitch removal circuit includes a first signal edge detector, a second signal edge detector, a latch, and a control signal generator. The first signal edge detector is activated according to the first control signal to detect the rising edge of the input signal to generate the first detection result. The second signal edge detector is activated according to the second control signal to detect the falling edge of the input signal to generate the second detection result. The latch sets the generated output signal according to the first detection result, and clears the generated output signal according to the second detection result. The control signal generator shields the glitch on the input signal to generate a processed signal, and generates a first control signal and a second control signal according to the processed signal.

Abstract: Disclosed is a tryptophan optical probe, a preparation method therefor and the use thereof. Disclosed is an optical probe, comprising a tryptophan-sensitive polypeptide or a functional variant thereof and an optically active polypeptide or a functional variant thereof, wherein the optically active polypeptide or the functional variant thereof is located in the sequence of the tryptophan-sensitive polypeptide or the functional variant thereof. Furthermore, disclosed are a method for preparing the above-mentioned probe and the use thereof in the detection of tryptophan.

Abstract: Methods, system and apparatus for video processing are described. One example method of processing video data includes performing a conversion between a current block of a video and a bitstream of the video. Samples of the current block are represented in the bitstream using coefficients that are arranged according to a rule responsive to locations of the samples of the current block.

Abstract: The present invention provides an anti-ErbB2 antibody-drug conjugate, a composition comprising the conjugate, a method for preparing the conjugate, and use of the conjugate.

Abstract: A method of video processing is described. The method includes: determining, based on a coding mode of a current video block of a video, whether a position dependent intra prediction combination (PDPC) method is used for coding the current video block based on a first rule, and performing a conversion between the current video block and a coded representation of the video according to the determining, wherein the PDPC method combines neighboring samples with a prediction signal of the current video block to generate a refined prediction signal of the current video block.

Abstract: A method of video processing includes determining, for a conversion between a video component of a video comprising a current video block and a bitstream representation of the video, that a first coding tool is used based on a rule for the current video block; and performing the conversion according to the determining, wherein the first coding tool includes transforming a representation of a visual signal between two color spaces, and where the rule specifies that a first quantization parameter (QP) offset for a luma channel of the current video block is equal to K1 and a second QP offset for a first chroma channel of the current video block is K1+O, where K1 and O are integers.

Abstract: The present invention provides a reagent and method for detecting a replication-competent lentivirus (RCL) by fluorescence quantitative real-time polymerase chain reaction (PCR). In particular, the present invention provides a primer and probe combination for detecting RCL, and a method for performing detection using said primer and probe; the present invention also provides a reagent kit comprising said primer and probe. The primer and probe combination of the present invention detects RCL with high amplification efficiency and good specificity, and can be used for RCL detection and RCL monitoring of clinical patient peripheral blood samples which may occur during a production process.

Abstract: An example method of video processing includes applying, in a conversion between a video comprising multiple components and a bitstream representation of the video, a deblocking filter to video blocks of the multiple components. A deblocking filter strength for the deblocking filter of each of the multiple components is determined according to a rule that specifies to use a different manner for determining the deblocking filter strength for the video blocks of each of the multiple components.

Abstract: Provided by the present application is a preparation, which comprises an antibody specifically bound with CD137 or an antigen-binding fragment thereof, wherein the CD137 antibody comprises a light chain variable region VL and a heavy chain variable region VH, wherein the VL comprises an amino acid sequence shown in any one of SEQ ID NO: 1-11, and the VH comprises an amino acid sequence shown in any one of SEQ ID NO:12-22. Also provided by the present application are a kit comprising the preparation, and a use of the preparation or the kit in the preparation of a drug, the drug being used for the treatment of a cancer.

Abstract: The embodiments of the present disclosure describe a stressed Ge PD and fabrications techniques for making the same. In one embodiment, a stressor material is deposited underneath an already formed Ge PD. To do so, wafer bonding can be used to bond the wafer containing the Ge PD to a second, handler wafer. Doing so provides support to remove the substrate of the wafer so that a stressor material (e.g., silicon nitride, diamond-like carbon, or silicon-germanium) can be disposed underneath the Ge PD. The stress material induces a stress or strain in the crystal lattice of the Ge which changes its bandgap and improves its responsivity.

Abstract: The invention relates to the field of biomedicine. In particular, the present invention relates to an interferon-based method for treating a disease, comprising intermittently administering an interferon-based therapeutic agent to a subject, where the disease is for example a viral infection or a cancer.

Abstract: The invention discloses a transistor structure including a substrate, a semiconductor layer disposed on the substrate and a gate layer disposed on the semiconductor layer, wherein the gate layer includes at least one gate having a first height, a first side and a second side opposite to the first side, a first dielectric spacer is disposed at the first side of the at least one gate, a first air spacer having a second height is disposed inside the first dielectric spacer, and the second height is lower than the first height.

Abstract: A heart valve prosthesis stent comprises an inner stent and an outer stent. The outer stent comprises an outer body section and an outer skirt section which extends from the outer body section and is located on the radial outer side of the outer body section. The inner stent comprises an inner body section at least partially located in the outer stent and an inner skirt section protruding out of the radial outer side of the inner body section from an inflow end of the inner body section. The inner skirt section (32) outwardly protrudes out of the radial outer side of the inflow end of the outer body section, the outer skirt section, the inner skirt section and the section of the outer body section located between the outer skirt section and the inner skirt section jointly form an accommodating space with an outward opening.

Abstract: The present disclosure describes the use of ectopic SOX2 to promote nerve growth and regeneration, particularly in the context of nerve deficit stemming from trauma and disease, by reprogramming non-nerve cells into neuronal cells. In particular, the disclosure provides for the use of SOX2 therapy, optionally combined with neurogenic growth factors, to treat nerve deficit conditions.

Abstract: Example implementations include a method, apparatus and computer-readable medium of video coding, comprising receiving the code block and one or more neighbor samples and determining the value of beta based on at least one of an average chroma value, a midrange chroma value, a median chroma value, an average luma value, a midrange luma value, or a median luma value of two or more neighbor samples.

Abstract: Described are systems, techniques, and processes for pathology detection in radiological images. A process can include obtaining a radiological image corresponding to an imaged anatomical area. Based on processing the radiological image using a semantic segmentation neural network, a target map can be generated corresponding to a plurality of candidate anatomical defect locations within the cropped radiological image. At least one volume of interest (VOI) can be generated centered around a particular candidate anatomical defect location within the cropped radiological image. A classification neural network can be used to classify the particular candidate anatomical defect location within the cropped radiological image, wherein classifying the particular candidate anatomical defect location includes determining a pathology associated with the particular candidate anatomical defect location.