Publication number: 20230071112
Abstract: The present invention relates to linkers having a group of propioloyl, substituted acryl (acryloyl), or disubstituted propanoyl, and using such linkers for the conjugation of compounds, in particular, cytotoxic agents to a cell-binding molecule.
Type:
Application
Filed:
June 8, 2022
Publication date:
March 9, 2023
Applicant:
Hangzhou DAC Biotech Co., Ltd.
Inventors:
Yongxin Robert ZHAO, Qingliang YANG, Yuanyuan HUANG, Shun GAI, Hangbo YE, Linyao ZHAO, Chengyu YANG, Huihui GUO, Xiaomai ZHOU, Hongsheng XIE, Haifeng ZHU, Yifang XU, Qianqian TONG, Junxiang JIA, Minjun CAO, Wenjun LI, Shuihong GAO, Zhixiang GUO, Lu BAI, Chen LI, Yanlei YANG, Chunyan WANG, Zhichang YE