Abstract: A cleaning device for a medical implement having a male protrusion. The cleaning device including a housing defining an inner cavity by and having an inner wall that encloses the inner cavity and an opening. The inner wall has a recess near the opening to the housing. The recess has a diameter that is greater than a diameter of the opening. The cap further includes a movable piston having a forward end and rearward end surrounded by a flexible flange that extends outward to abut the inner wall near the recess of the housing. The rearward end of the movable piston configured to contact couple with a distal end of the male protrusion to move the piston toward a distal end of the housing opposite the opening of the housing to provide a portion of the cleaning solution to the male protrusion.