Patents by Inventor Lian Leon

Lian Leon has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Flowable pharmaceutical depot
    Patent number: 8822546
    Abstract: Flowable pharmaceutical depots are described. The flowable pharmaceutical depot includes a polyester, such as a polylactic acid or a poly(trimethylene carbonate) endcapped with a primary alcohol and a pain relieving therapeutic agent, such as a post operative pain relieving therapeutic agent. Method of making and using the same are also described.
    Type: Grant
    Filed: December 1, 2008
    Date of Patent: September 2, 2014
    Assignee: Medtronic, Inc.
    Inventors: Michael Eric Benz, Christopher M. Hobot, Phillip Edward McDonald, Lian Leon Luo, John Kramer
  • Therapeutic polymers and methods of generation
    Patent number: 8106146
    Abstract: The invention describes poly(ortho ester) polymers that include at least one therapeutic compound in the polymer backbone. The therapeutic compound includes at least one phenol residue and an aliphatic alcohol residue or two or more phenolic residues.
    Type: Grant
    Filed: April 23, 2010
    Date of Patent: January 31, 2012
    Assignee: Medtronic, Inc.
    Inventors: Michael E. Benz, Erica M. Tenbroek, Lian Leon
  • THERAPEUTIC POLYMERS AND METHODS OF GENERATION
    Publication number: 20110082266
    Abstract: The invention describes poly(ortho ester) polymers that include at least one therapeutic compound in the polymer backbone. The therapeutic compound includes at least one phenol residue and an aliphatic alcohol residue or two or more phenolic residues.
    Type: Application
    Filed: April 23, 2010
    Publication date: April 7, 2011
    Inventors: Michael Eric Benz, Erica M. TenBroek, Lian Leon Luo
  • Polymerization of Multifunctional Azides, and Polymers Therefrom
    Publication number: 20110065809
    Abstract: Methods for preparing polymers from multifunctional azides and multifunctional azide-reactants are described in the present disclosure. Exemplary multifunctional azide-reactants include multifunctional alkynes and/or multifunctional ?-phosphine esters. In certain embodiments, such polymers can be prepared in vivo. Such polymers can be useful in a wide variety of biomedical applications.
    Type: Application
    Filed: September 15, 2009
    Publication date: March 17, 2011
    Applicant: Medtronic, Inc.
    Inventors: Michael Eric Benz, Lian Leon Luo, Metasebia T. Munie
  • POLYKETAL POLYMERS, AND METHODS OF MAKING AND USING SAME
    Publication number: 20100255051
    Abstract: Polyketal polymers, and methods of making and using such polyketal polymers are disclosed herein. The polyketal poylmers can be useful for applications including, for example, medical devices and pharmaceutical compositions. In a preferred embodiment, the polyketal polymers are biodegradable.
    Type: Application
    Filed: June 18, 2010
    Publication date: October 7, 2010
    Inventors: Michael Eric Benz, Lian Leon Luo
  • HETEROATOM-CONTAINING POLYMERS AND METATHESIS POLYMERIZATION METHODS FOR MAKING SAME
    Publication number: 20100240852
    Abstract: Heteroatom-containing polymers such as polyketals, and methods of making and using such heteroatom-containing polymers are disclosed herein. The heteroatom-containing polymers can be useful for applications including, for example, medical devices and pharmaceutical compositions. In a preferred embodiment, the heteroatom-containing polymers are polyketals that are biodegradable.
    Type: Application
    Filed: March 22, 2010
    Publication date: September 23, 2010
    Applicant: Medtronic, Inc.
    Inventors: Lian Leon Luo, Michael Eric Benz
  • Polyketal polymers, and methods of making and using same
    Patent number: 7741375
    Abstract: Polyketal polymers, and methods of making and using such polyketal polymers are disclosed herein. The polyketal poylmers can be useful for applications including, for example, medical devices and pharmaceutical compositions. In a preferred embodiment, the polyketal polymers are biodegradable.
    Type: Grant
    Filed: February 15, 2007
    Date of Patent: June 22, 2010
    Assignee: Medtronic, Inc
    Inventors: Michael Eric Benz, Lian Leon Luo
  • FLOWABLE PHARMACEUTICAL DEPOT
    Publication number: 20100137369
    Abstract: Flowable pharmaceutical depots are described. The flowable pharmaceutical depot includes a polyester, such as a polylactic acid or a poly(trimethylene carbonate) endcapped with a primary alcohol and a pain relieving therapeutic agent, such as a post operative pain relieving therapeutic agent. Method of making and using the same are also described.
    Type: Application
    Filed: December 1, 2008
    Publication date: June 3, 2010
    Applicant: Medtronic, Inc.
    Inventors: Michael Eric BENZ, Christopher M. Hobot, Phillip Edward McDonald, Lian Leon Luo, John Kramer
  • MEDICAL DEVICES, POLYMERS, COMPOSITIONS, AND METHODS FOR DELIVERING A HALOACETATE
    Publication number: 20090269390
    Abstract: Polymers, compositions, and medical devices useful for delivering (e.g., by local and/or sustained delivery) a haloacetate (e.g., dichoroacetate) to a tissue are disclosed herein. Such methods can be useful for treatment of diseases such as cancer.
    Type: Application
    Filed: April 23, 2009
    Publication date: October 29, 2009
    Applicant: Medtronic, Inc.
    Inventors: Lian Leon Luo, Michael Eric Benz, Christopher M. Hobot, SuPing Lyu
  • Methods of inhibiting or suppressing cellular proliferation
    Publication number: 20090061515
    Abstract: Methods of inhibiting or suppressing cellular proliferation are disclosed that include delivering at least one antiproliferative agent into or proximate a cell. In certain embodiments, the antiproliferative agent(s) are hydrolysis products of a biodegradable polymer (e.g., a polyketal polymer).
    Type: Application
    Filed: August 29, 2007
    Publication date: March 5, 2009
    Inventors: Michael Eric Benz, Timothy H. Robinson, Lian Leon Luo, Jesus Casas-Bejar, Maura Donovan, Krystal King