Abstract: Provided are a knob mechanism with an easily replaceable cap and a lacing device including the same. The knob mechanism includes an inner knob and a cap, and the cap is detachably mounted on an outer side of the inner knob. The cap is provided with at least one locking block. The inner knob is provided with at least one separating and coupling mechanism. The locking block and the separating and coupling mechanism cooperate to achieve coupling and separation between the inner knob and the cap. The separating and coupling mechanism includes a locking portion and a separating groove. The locking block and the locking portion are securely engaged, thereby forming mechanical coupling between the cap and the inner knob. The cap is rotatable relative to the inner knob to rotate the locking block to the separating groove, thereby separating the cap and the inner knob from the separating groove.

Abstract: An oral liquid composition contains fingolimod or a pharmaceutically acceptable salt thereof. The oral liquid composition at least contains fingolimod or a pharmaceutically acceptable salt thereof, cyclodextrin, a metal complexing agent, and water. The mass ratio of the cyclodextrin to the fingolimod or the pharmaceutically acceptable salt thereof is 70-200:1. The composition has a pH of 3-6. By means of adding the metal complexing agent, providing the specific amount of cyclodextrin, and controlling the pH of the composition, the problems of physical and chemical instability of fingolimod in the oral liquid composition caused by of iron ion leaching in the production line, long-time storage, environmental change, etc. are solved.

Abstract: An accessory holder and a maintenance station system. The accessory holder includes: an accommodating tray configured to accommodate an accessory of a surface cleaning device; and an accommodating rod located on one side of the accommodating tray and configured to accommodate a brush head provided with an extension rod, where the accommodating rod includes a first accommodating position, a second accommodating position, and a third accommodating position, the first accommodating position and the second accommodating position implement a first accommodating posture of the brush head, and the first accommodating position and the third accommodating position implement a second accommodating posture of the brush head.

Abstract: Provided herein are methods of treating a skin-related disease or disorder (such as melasma). Also provided are pharmaceutical compositions of midostaurin or a pharmaceutically acceptable salt thereof formulated for topical administration. Further described are methods for preparing such topical pharmaceutical compositions and methods of using the same for treating a subject.

Abstract: The present disclosure relates to a brake calliper housing for use for an electromechanically actuable brake actuator having a recess to accommodate a brake piston. The recess is delimited by a cylindrical recess wall, extending in an axial direction into the brake calliper housing, and by a recess bottom. The recess has a recess opening situated opposite the recess bottom. The brake calliper housing has a guide slot, let into the recess wall, to accommodate a guide element for securing the brake piston against rotation. The longitudinal extent of the guide slot runs parallel to the axial direction. The guide slot is of circular design in cross section.

Abstract: A seal assembly for a brake piston assembly has an encircling fixing portion, and a seal portion which can be extended and/or compressed axially. The seal portion has a fastening element, spaced apart axially from the fixing portion by a first distance and is arranged closer to the axial end of a brake piston than the fixing portion, and a first connection portion, which is spaced apart axially from the fastening element by a second distance, which is smaller than the first distance, or is not spaced apart axially from the fastening element, and by which the seal portion is connected to the fixing portion. The seal assembly has sealing lip connected to the fixing portion by a second connection portion spaced apart axially from the fastening element by a third distance, which is greater than the second distance.

Abstract: This disclosure relates to polysiloxanes and polysiloxane compositions having dual-curable properties, to methods for forming articles from such compositions, and to articles formed thereby. In one embodiment, the polysiloxane comprises at least about two alkenyl groups and at least about two (meth)acryloyl groups.

Abstract: The present disclosure provides a recombinant Escherichia coli for producing chlorogenic acid and application thereof. In the present disclosure, tyrosine ammonia-lyase FjTAL derived from Flavobacterium johnsoniae, hpaBC derived from E. coli, 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase mutant aroGfbr, chorismate mutase tyrC derived from Zymomonas mobilis, quinic acid/shikimate-5 dehydrogenase ydiB derived from E. coli, hydroxycinnamoyl CoA:quinic acid transferase NtHQT derived from Nicotiana tabacum, and 4-coumarate:CoA ligase At4CL1 derived from Arabidopsis thaliana are expressed in the recombinant E. coli, thereby constructing a chlorogenic acid biosynthesis pathway in E. coli. Then, the aroB gene and gldA gene derived from E. coli are overexpressed, and an endogenous gene menI is knocked out from the recombinant E. coli. The recombinant strain produced chlorogenic acid by fermentation at a titer of up to 638.2 mg/L in a shake flask or at a titer of 2.8 g/L in a 5-L fermenter.

Abstract: The disclosure provides trusted user interface display methods. One example method applied to an electronic device having a foldable screen, includes: changing the foldable screen from a first display status to a second display status in response to a first operation performed by a user on the electronic device; displaying a user interface (UI) of a client application (CA) on a screen corresponding to the second display status; and triggering to display a trusted user interface (TUI) corresponding to the CA on the screen corresponding to the second display status in response to a second operation performed by the user on the UI of the CA, where the TUI is adapted to the screen corresponding to the second display status.

Abstract: A two-dimensional code processing method and a device. The method includes: obtaining, by a first electronic device, two-dimensional code information displayed by a second electronic device; obtaining first scenario information, where the first scenario information is scenario information related to the first electronic device; determining two-dimensional code data and second scenario information based on the two-dimensional code information, where the second scenario information is scenario information related to the second electronic device; and when determining that the first scenario information and the second scenario information meet a preset condition, performing, by the first electronic device, preset processing on the two-dimensional code data. The scenario information of the two electronic devices that need to perform two-dimensional code interaction is compared, and further, two-dimensional code verification is completed.

Abstract: This disclosure relates to polysiloxanes and polysiloxane compositions having dual-curable properties, to methods for forming articles from such compositions, and to articles formed thereby. In one embodiment, the polysiloxane comprises at least about two alkenyl groups and at least about two (meth)acryloyl groups.

Abstract: An image display method includes drawing a first graph in a trusted execution environment (TEE). The method also includes displaying the first graph on a first layer in a display screen. The method further includes drawing a second graph in a rich execution environment (REE). The method additionally includes displaying the second graph on a second layer in the display screen. The first layer is located above the second layer. The first graph includes a transparent area and a non-transparent area. The non-transparent area includes content drawn in the TEE. A display area that is on the second graph and that corresponds to the transparent area includes content drawn in the REE. When the first layer and the second layer are overlapped for displaying, the transparent area does not shield the content drawn in the REE.

Abstract: The present disclosure discloses a recombinant Escherichia coli for producing rosmarinic acid and application thereof, belonging to the technical fields of genetic engineering and bioengineering. In the present disclosure, FjTA derived from Flavobacterium johnsoniae, endogenous hpaBC derived from E. coli, CbRAS derived from Coleus blumei, HPPR derived from Coleus scutellarioides, and Pc4CL1 derived from Petroselinum crispum are heterologously expressed in E. coli, realizing synthesis of rosmarinic acid. TcTAL derived from Trichosporon cutaneum and tyrC for removing feedback inhibition are introduced, further increasing synthesis throughput of caffeic acid, and PmLAAD derived from Proteus myxofaciens is heterologously expressed, realizing redistribution of L-DOPA. An endogenous gene menl is knocked out, improving the content and stability of a rosmarinic acid precursor. The recombinant strain constructed in the present disclosure can produce rosmarinic acid by fermentation at a yield of up to 511.

Abstract: The present disclosure discloses a multi-stage apparatus and process for advanced oxidation treatment of wastewater, and belongs to the field of wastewater treatment in environmental protection. The apparatus includes a liquid-liquid mixing unit, a preheating unit, a gas-liquid mixing unit, a parallel photocatalytic reactor group and an oxidation tower connected in sequence. According to characteristics of free radical reactions, the parallel photocatalytic reactor group and the oxidation tower in the apparatus are reasonably designed, utilization rates of the ozone and the hydrogen peroxide are increased, and the wastewater treatment cost is reduced.

Abstract: The present disclosure relates generally to photocurable compositions and methods for continuously forming a three-dimensional body from these compositions. More particularly, the present disclosure relates to photocurable compositions comprising a mixture of polysiloxanes capable of being dually cured, i.e., first by UV radiation followed by thermal treatment, or being cured by UV radiation. In one aspect, the disclosure provides a photocurable composition, including: a first polysiloxane comprising at least two acrylate or methacrylate groups per molecule; a second polysiloxane containing at least one (e.g., at least two) Si—H group per molecule; a third polysiloxane containing at least one (e.g., at least two) reactive aliphatic ethylene group per molecule; a free radical photoinitiator in an amount of about 0.01 to about 10 weight % based on the total weight of (meth)acrylate-containing polysiloxane in the composition; and a hydrosilylation catalyst in an amount of about 0.

Abstract: A two-dimensional code processing method and a device. The method includes: obtaining, by a first electronic device, two-dimensional code information displayed by a second electronic device; obtaining first scenario information, where the first scenario information is scenario information related to the first electronic device; determining two-dimensional code data and second scenario information based on the two-dimensional code information, where the second scenario information is scenario information related to the second electronic device ; and when determining that the first scenario information and the second scenario information meet a preset condition, performing, by the first electronic device, preset processing on the two-dimensional code data. The scenario information of the two electronic devices that need to perform two-dimensional code interaction is compared, and further, two-dimensional code verification is completed.

Abstract: An image display method provided is applicable to the electronic device that includes a trusted execution environment (TEE) and a rich execution environment (REE). The TEE draws a first graph, and displays the first graph on a first layer in a display screen; and the REE draws a second graph, and displays the second graph on a second layer; and the first graph includes a transparent area and a non-transparent area, the non-transparent area includes content drawn by the TEE, a display area that is on the second graph and that corresponds to the transparent area includes content drawn by the REE, and when the first layer and the second layer are overlapped for displaying, the transparent area does not shield the content drawn by the REE. Richness of a trusted user interface (TUI) is improved by using a powerful drawing capability of the REE.

Abstract: This application discloses a trusted user interface display method. The method is applied to an electronic device having a foldable screen, includes: changing the foldable screen from a first display status to a second display status in response to a first operation performed by a user on the electronic device; displaying a user interface UI of a CA on a screen corresponding to the second display status; and triggering to display a trusted user interface TUI corresponding to the CA on the screen corresponding to the second display status in response to a second operation performed by the user on the of the CA, where the TUI is adapted to the screen corresponding to the second display status. In this application, the trusted user interface (TUI) of a TA corresponding to the CA can automatically adapt to a screen change of the foldable screen, thereby improving user experience.

Abstract: Provided is an apparatus for preparing a building structure with 3D printing, comprising: a 3D printing device (1), having a storage chamber (11) and a printing head (12) connected to the storage chamber (11) and being movable relative to a base frame; and a reinforcing device, movably disposed relative to the base frame, and having a driving mechanism (3) for driving short rebars or short ribs to perform an insertion movement in a direction intersected with a stacking direction of a cement-based slurry layer; the driving mechanism inserts the short rebars or the short ribs into an interlayer interface spanning at least two adjacent cement-based slurry layers printed by the 3D printing device (1). Also provided a method for preparing a building structure with 3D printing.