Abstract: A network switch includes a plurality of ports for communicating over a network. Processing circuitry processes inbound frames received from the network via the ports and sends outbound frames to the network. Remote management circuitry (RMU) is responsive to commands received from a host device external to the network switch. The RMU receives via one of the ports a remote access request frame from the host device, wherein at least part of the remote access request frame is encrypted, and decrypts the remote access request frame. In response to successful decryption of the part of the remote access request frame, the RMU accesses one or more configuration registers of the network switch in accordance with the remote access request frame, composes a remote access response frame, at least a portion of the remote access response frame being encrypted, and sends the remote access response frame to the host device.

Abstract: The present disclosure discloses a recombinant Escherichia coli for producing rosmarinic acid and application thereof, belonging to the technical fields of genetic engineering and bioengineering. In the present disclosure, FjTA derived from Flavobacterium johnsoniae, endogenous hpaBC derived from E. coli, CbRAS derived from Coleus blumei, HPPR derived from Coleus scutellarioides, and Pc4CL1 derived from Petroselinum crispum are heterologously expressed in E. coli, realizing synthesis of rosmarinic acid. TcTAL derived from Trichosporon cutaneum and tyrC for removing feedback inhibition are introduced, further increasing synthesis throughput of caffeic acid, and PmLAAD derived from Proteus myxofaciens is heterologously expressed, realizing redistribution of L-DOPA. An endogenous gene menl is knocked out, improving the content and stability of a rosmarinic acid precursor. The recombinant strain constructed in the present disclosure can produce rosmarinic acid by fermentation at a yield of up to 511.

Abstract: Methods and electronic devices for measuring motion and acoustic signatures of physiological processes of a human subject. The method includes measuring motion and acoustic signatures of physiological processes of a human subject; sending the first feature-related data to a machine learning service; sending the first feature-related data to a machine learning service; and determining a predicted detection of human scratching activity by the machine-learning service by performing a machine-learning operation on the feature-related data.

Abstract: A photo taking control method and system based on a mobile terminal, and a storage medium. The method comprises: a photo sharing platform pre-stores photos and photos taking positions, and arranges the photos at the same position in descending order according to degrees of attention; a mobile terminal obtains position information of the current position of a user in real time and sends the position information to the photo sharing platform; when retrieving the stored photos at the same position according to the position information, the photo sharing platform sends ahead photos to the mobile terminal.

Abstract: Disclosed in the present invention are a method for controlling multi-mode charging, a mobile terminal, and a storage medium. The method comprises: pre-configuring multiple charging modes; connecting a charger, and receiving a user operation instruction, the operation instruction comprising a mode selection instruction; configuring and starting a timer according to a preset charging mode and the received operation instruction; and disabling or enabling a charging function when the time period set in the timer has passed.

Abstract: A photo taking control method and system based on a mobile terminal, and a storage medium. The method comprises: a photo sharing platform pre-stores photos and photos taking positions, and arranges the photos at the same position in descending order according to degrees of attention; a mobile terminal obtains position information of the current position of a user in real time and sends the position information to the photo sharing platform; when retrieving the stored photos at the same position according to the position information, the photo sharing platform sends ahead photos to the mobile terminal.

Abstract: Disclosed in the present invention are a method for controlling multi-mode charging, a mobile terminal, and a storage medium. The method comprises: pre-configuring multiple charging modes; connecting a charger, and receiving a user operation instruction, the operation instruction comprising a mode selection instruction; configuring and starting a timer according to a preset charging mode and the received operation instruction; and disabling or enabling a charging function when the time period set in the timer has passed.

Abstract: This invention discloses a system and a method for extracting VF signal in ECG recorded during uninterrupted CPR. The present invention provides a method for extracting a Ventricular fibrillation (VF) signal in Electrocardiography (ECG), comprising: receiving an ECG signal; adding a plurality of shadowing functions to the ECG signal, to obtain a plurality of modification signals; decomposing the plurality of modification signals by using an Empirical Mode Decomposition (EMD) method, to generate a plurality of Intrinsic Mode Functions (IMFs); calculating the sum of IMFs in different frequency regions based on time sequence, dividing by a number of the shadowing signal, to obtain a plurality of modification intrinsic mode functions; combining the plurality of modification IMFs with the same property, to obtain a shape function; modeling the shape functions to obtain a compression signal; and subtracting the compression signal from the ECG signal based on time sequence, to obtain the VF signal.

Abstract: This invention discloses a system and a method for extracting VF signal in ECG recorded during uninterrupted CPR. The present invention provides a method for extracting a Ventricular fibrillation (VF) signal in Electrocardiography (ECG), comprising: receiving an ECG signal; adding a plurality of shadowing functions to the ECG signal, to obtain a plurality of modification signals; decomposing the plurality of modification signals by using an Empirical Mode Decomposition (EMD) method, to generate a plurality of Intrinsic Mode Functions (IMFs); calculating the sum of IMFs in different frequency regions based on time sequence, dividing by a number of the shadowing signal, to obtain a plurality of modification intrinsic mode functions; combining the plurality of modification IMFs with the same property, to obtain a shape function; modeling the shape functions to obtain a compression signal; and subtracting the compression signal from the ECG signal based on time sequence, to obtain the VF signal.

Abstract: This invention discloses a system and method for extracting VF signal in ECG recorded during uninterrupted CPR. The method and system applies an adaptive algorithm incorporating the EMD and least mean square (LMS) filtering to effectively model the CPR artifacts such as chest compression signals. Thus, A VF signal in ECG recorded during uninterrupted CPR can be extracted without deteriorating the reliability of the waveform parameter (i.e. AMSA) of shockability. The present invention enables uninterrupted CPR performed during recording ECG for accessing the shockability, so that an increase the probability of successful resuscitation is achieved.

Abstract: The present invention provides surface-stabilized amorphous pharmaceuticals comprising an amorphous pharmaceutical substrate coated with a biocompatible immobilizing material. Amorphous pharmaceutical substrates that are prone to surface enhanced crystallization benefit from the present coatings. The coated amorphous pharmaceuticals of the present invention maintain their amorphous state and, therefore, their solubility over extended periods of time, relative to uncoated pharmaceuticals.

Abstract: This invention discloses a system and method for extracting VF signal in ECG recorded during uninterrupted CPR. The method and system applies an adaptive algorithm incorporating the EMD and least mean square (LMS) filtering to effectively model the CPR artifacts such as chest compression signals. Thus, A VF signal in ECG recorded during uninterrupted CPR can be extracted without deteriorating the reliability of the waveform parameter (i.e. AMSA) of shockability. The present invention enables uninterrupted CPR performed during recording ECG for accessing the shockability, so that an increase the probability of successful resuscitation is achieved.

Abstract: A viable strategy to enhance the bioavailability of poorly soluble drugs is to use amorphous solids in place of the more commonly used crystalline solids in pharmaceutical formulations. However, amorphous solids are physically meta-stable and tend to revert back to their crystalline counterpart. An effective approach to stabilizing an amorphous drug against crystallization is to disperse it in a polymer matrix. The drug's solubility in the chosen polymer defines the upper limit of drug loading without any risk of crystallization. Measuring the solubility of a drug in a polymer has been a scientific and technological challenge because the high viscosity of polymers makes achieving solubility equilibrium difficult and because pharmaceutically important drug/polymer dispersions are glasses, which undergo structural relaxation over time. The invention provides a method based on Differential Scanning calorimetry (DSC) for measuring the solubility of crystalline drugs in polymeric matrices.

Abstract: A method for evaluating the solubility of a crystalline substance in a polymer comprises a) providing at least one sample of an intimate crystalline substance/polymer mixture at a predetermined crystalline substance concentration; b) annealing the sample at a constant temperature Ta for a period of time; c) heating the annealed sample while recording the heat flux over time by DSC; d) identifying a DSC dissolution endotherm in the recorded heat flux, if any; e) considering the crystalline substance concentration as a concentration above the crystalline substance solubility in the polymer at temperature Ta when there is a DSC dissolution endotherm identified, and considering the crystalline substance concentration as a concentration less than or equal to the crystalline substance solubility in the polymer at temperature Ta when there is no DSC dissolution endotherm identified.

Abstract: A computer-assisted method for quantitative characterization and treatment of ventricular fibrillation includes acquiring a time series of a ventricular fibrillation (VF) signal using a probe from a patient experiencing VF, subtracting the mean from the time series of the VF signal, calculating a cumulative VF signal after the mean is subtracted from the time series of the VF signal, segmenting the cumulative VF signal by a plurality of sampling boxes, calculating the root-mean-square of the cumulative VF signal as a function of the sampling box size , extracting an exponent of the root-mean-square of the cumulative VF signal as a function of the sampling box size, applying electrical defibrillation to the patient if the exponent is below a predetermined value, and applying cardiopulmonary resuscitation (CPR) to the patient if the exponent is above a predetermined value.

Abstract: The present invention provides vapor deposition methods that overcome the kinetic restrictions imposed by more conventional vapor deposition processes and liquid-cooling techniques to form amorphous molecular solids with greatly enhanced stabilities. The present methods produce amorphous molecular solids having stabilities, as measured by fictive temperature, that cannot be achieved using liquid-cooling methods.

Abstract: A computer-assisted method for quantitative characterization and treatment of ventricular fibrillation includes acquiring a time series of a ventricular fibrillation (VF) signal using a probe from a patient experiencing VF, subtracting the mean from the time series of the VF signal, calculating a cumulative VF signal after the mean is subtracted from the time series of the VF signal, segmenting the cumulative VF signal by a plurality of sampling boxes, calculating the root-mean-square of the cumulative VF signal as a function of the sampling box size , extracting an exponent of the root-mean-square of the cumulative VF signal as a function of the sampling box size, applying electrical defibrillation to the patient if the exponent is below a predetermined value, and applying cardiopulmonary resuscitation (CPR) to the patient if the exponent is above a predetermined value.

Abstract: A viable strategy to enhance the bioavailability of poorly soluble drugs is to use amorphous solids in place of the more commonly used crystalline solids in pharmaceutical formulations. However, amorphous solids are physically meta-stable and tend to revert back to their crystalline counterpart. An effective approach to stabilizing an amorphous drug against crystallization is to disperse it in a polymer matrix. The drug's solubility in the chosen polymer defines the upper limit of drug loading without any risk of crystallization. Measuring the solubility of a drug in a polymer has been a scientific and technological challenge because the high viscosity of polymers makes achieving solubility equilibrium difficult and because pharmaceutically important drug/polymer dispersions are glasses, which undergo structural relaxation over time. The invention provides a method based on Differential Scanning calorimetry (DSC) for measuring the solubility of crystalline drugs in polymeric matrices.

Abstract: The present invention provides surface-stabilized amorphous pharmaceuticals comprising an amorphous pharmaceutical substrate coated with a biocompatible immobilizing material. Amorphous pharmaceutical substrates that are prone to surface enhanced crystallization benefit from the present coatings. The coated amorphous pharmaceuticals of the present invention maintain their amorphous state and, therefore, their solubility over extended periods of time, relative to uncoated pharmaceuticals.

Abstract: The present invention provides vapor deposition-methods that overcome the kinetic restrictions imposed by more conventional vapor deposition processes and liquid-cooling techniques to form amorphous molecular solids with greatly enhanced-stabilities. The present methods produce amorphous molecular solids having stabilities, as measured by fictive temperature, that cannot be achieved using liquid-cooling methods.