Patents by Inventor Liana Lagniton

Liana Lagniton has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

MITOTIC KINESIN INHIBITORS

Publication number: 20090171082

Abstract: The present invention relates to compounds that are useful for treating cellular proliferative diseases, for treating disorders mediated, at least in part, by KSP, and for inhibiting KSP. The invention also related to pharmaceutical compositions comprising such compounds, methods of treating cancer by the administration of such compositions, and processes for the preparation of the compounds.

Type: Application

Filed: March 4, 2009

Publication date: July 2, 2009

Inventors: Weibo Wang, Ryan Constantine, Liana Lagniton
Mitotic kinesin inhibitors

Patent number: 7504405

Abstract: The present invention relates to compounds that are useful for treating cellular proliferative diseases, for treating disorders mediated, at least in part, by KSP, and for inhibiting KSP. The invention also related to pharmaceutical compositions comprising such compounds, methods of treating cancer by the administration of such compositions, and processes for the preparation of the compounds.

Type: Grant

Filed: April 6, 2005

Date of Patent: March 17, 2009

Assignee: Novartis Vaccines and Diagnostics, Inc.

Inventors: Weibo Wang, Ryan Constantine, Liana Lagniton
HETEROARYL-FUSED PYRIMIDINYL COMPOUNDS AS ANTICANCER AGENTS

Publication number: 20080069817

Abstract: Heteroaryl-fused pyrimidinyl compounds, pharmaceutically acceptable salts, and prodrugs thereof; compositions that include a pharmaceutically acceptable carrier and one or more of the heteroaryl-fused pyrimidinyl compounds, either alone or in combination with at least one additional therapeutic agent. Methods of using the heteroaryl-fused pyrimidinyl compounds, either alone or in combination with at least one additional therapeutic agent, in the prophylaxis or treatment of proliferative diseases.

Type: Application

Filed: September 27, 2007

Publication date: March 20, 2008

Applicant: CHIRON CORPORATION

Inventors: Weibo Wang, Liana Lagniton, Ryan Constantine, Matthew Burger
Substituted imidazole compounds as KSP inhibitors

Publication number: 20070037853

Abstract: The present invention relates to new substituted imidazole compounds and pharmaceutically acceptable salts, esters or prodrugs thereof, compositions of the derivatives together with pharmaceutically acceptable carriers, and uses of the compounds.

Type: Application

Filed: August 9, 2006

Publication date: February 15, 2007

Inventors: Paul Barsanti, Yi Xia, Weibo Wang, Kris Mendenhall, Liana Lagniton, Savithri Ramurthy, Megan Phillips, Sharadha Subramanian, Rustum Boyce, Nathan Brammeier, Ryan Constantine, David Duhl, Annette Walter, Tinya Abrams, Paul Renhowe
Substituted imidazole derivatives

Publication number: 20060009472

Abstract: The present invention relates to new substituted imidazole compounds and pharmaceutically acceptable salts, esters or prodrugs thereof, compositions of the new compounds together with pharmaceutically acceptable carriers, and uses of the new compounds.

Type: Application

Filed: June 20, 2005

Publication date: January 12, 2006

Inventors: Weibo Wang, Paul Barsanti, Yi Xia, Rustum Boyce, Sabina Pecchi, Nathan Brammeier, Megan Phillips, Kris Mendenhall, Kelly Wayman, Liana Lagniton, Ryan Constantine, Hong Yang, Elizabeth Mieuli, Savithri Ramurthy, Elisa Jazan, Anu Sharma, Rama Jain, Sharadha Subramanian, Paul Renhowe, Kenneth Bair, David Duhl, Annette Walter, Tinya Abrams, Kay Huh, Eric Martin, Mark Knapp, Vincent Le
Substituted quinoline derivatives

Publication number: 20050261337

Abstract: The present invention relates to new substituted quinoline compounds and pharmaceutically acceptable salts, esters or prodrugs thereof, compositions of the new compounds together with pharmaceutically acceptable carriers, and uses of the new compounds.

Type: Application

Filed: May 19, 2005

Publication date: November 24, 2005

Inventors: Weibo Wang, Ryan Constantine, Liana Lagniton, Kenneth Bair
Mitotic kinesin inhibitors

Publication number: 20050228002

Abstract: The present invention relates to compounds that are useful for treating cellular proliferative diseases, for treating disorders mediated, at least in part, by KSP, and for inhibiting KSP. The invention also related to pharmaceutical compositions comprising such compounds, methods of treating cancer by the administration of such compositions, and processes for the preparation of the compounds.

Type: Application

Filed: April 6, 2005

Publication date: October 13, 2005

Applicant: Chiron Corporation

Inventors: Weibo Wang, Ryan Constantine, Liana Lagniton
Quinazolinone compounds as anticancer agents

Publication number: 20050209254

Abstract: Quinazolinone compounds, pharmaceutically acceptable salts, and prodrugs thereof; compositions that include a pharmaceutically acceptable carrier and one or more of the quinazolinone compounds, either alone or in combination with at least one additional therapeutic agent. Methods of using the quinazolinone compounds, either alone or in combination with at least one additional therapeutic agent, in the prophylaxis or treatment of proliferative diseases.

Type: Application

Filed: November 24, 2004

Publication date: September 22, 2005

Inventors: Weibo Wang, Liana Lagniton, Ryan Constantine, Manoj Desai
Pyridino[1,2-a]pyrimidin-4-one compounds as anticancer agents

Publication number: 20050085490

Abstract: Pyridin[1,2-a]pyrimidinyl compounds, pharmaceutically acceptable salts, and prodrugs thereof; compositions that include a pharmaceutically acceptable carrier and one or more of the pyridino[1,2-a]pyrimidinyl compounds, either alone or in combination with at least one additional therapeutic agent. Methods of using the pyridino[1,2-a]pyrimidinyl compounds, either alone or in combination with at least one additional therapeutic agent, in the prophylaxis or treatment of proliferative diseases.

Type: Application

Filed: June 17, 2004

Publication date: April 21, 2005

Inventors: Weibo Wang, Ryan Constantine, Liana Lagniton, Sabina Pecchi, Matthew Burger, Manoj Desai
Thiosemicarbazones as anti-virals and immunopotentiators

Publication number: 20050069555

Abstract: The present invention is directed to novel immune potentiators, novel vaccine adjuvants, novel compounds and pharmaceutical compositions, novel methods for treating viral infections, including HCV, by administering the compounds, and novel methods for modulating an immune response by administering the compounds.

Type: Application

Filed: December 29, 2003

Publication date: March 31, 2005

Inventors: Paul Barsanti, Nathan Brammeier, Anthony Diebes, Liana Lagniton, Simon Ng, Zhi-Jie Ni, Keith Pfister, Casey Philbin, Nicholas Valiante, Allan Wagman, Weibo Wang, Amy Weiner
Heteroaryl-fused pyrimidinyl compounds as anticancer agents

Publication number: 20050065169

Abstract: Heteroaryl-fused pyrimidinyl compounds, pharmaceutically acceptable salts, and prodrugs thereof; compositions that include a pharmaceutically acceptable carrier and one or more of the heteroaryl-fused pyrimidinyl compounds, either alone or in combination with at least one additional therapeutic agent. Methods of using the heteroaryl-fused pyrimidinyl compounds, either alone or in combination with at least one additional therapeutic agent, in the prophylaxis or treatment of proliferative diseases.

Type: Application

Filed: May 21, 2004

Publication date: March 24, 2005

Inventors: Weibo Wang, Liana Lagniton, Ryan Constantine, Matthew Burger