Patents by Inventor Liana Lee

Liana Lee has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Antibodies that bind to BGS-4
    Publication number: 20090088385
    Abstract: The present invention provides novel polynucleotides encoding BGS-4 polypeptides, fragments and homologues thereof. Also provided are vectors, host cells, antibodies, and recombinant and synthetic methods for producing the polypeptides of the present invention. The invention further relates to diagnostic and therapeutic methods for applying these novel BGS-4 polypeptides to the diagnosis, treatment, and/or prevention of various diseases and/or disorders related to these polypeptides. The invention further relates to screening methods for identifying agonists and antagonists of the polynucleotides and polypeptides of the present invention.
    Type: Application
    Filed: September 10, 2008
    Publication date: April 2, 2009
    Inventors: Shujian Wu, Stanley R. Krystek, Liana Lee, John N. Feder, Janet D. Cheng
  • Human phosphatase RET31, and variants thereof
    Patent number: 7358074
    Abstract: The present invention provides novel polynucleotides encoding human phosphatase polypeptides, fragments and homologues thereof. Also provided are vectors, host cells, antibodies, and recombinant and synthetic methods for producing said polypeptides. The invention further relates to diagnostic and therapeutic methods for applying these novel human phosphatase polypeptides to the diagnosis, treatment, and/or prevention of various diseases and/or disorders related to these polypeptides, particularly cardiovascular diseases and/or disorders. The invention further relates to screening methods for identifying agonists and antagonists of the polynucleotides and polypeptides of the present invention.
    Type: Grant
    Filed: June 2, 2005
    Date of Patent: April 15, 2008
    Assignee: Bristol-Myers Squibb Company
    Inventors: Donald G. Jackson, Chandra S. Ramanathan, Liana Lee, Nathan Siemers, Suzanne J. Suchard, Joshua Finger, C. Gordon Todderud, Dana Banas
  • Polynucleotides encoding a novel testis-specific tubulin tyrosine-ligase-like protein, BGS42
    Publication number: 20080026401
    Abstract: The present invention provides novel polynucleotides encoding BGS-42 polypeptides, fragments and homologues thereof. Also provided are vectors, host cells, antibodies, and recombinant and synthetic methods for producing said polypeptides. The invention further relates to diagnostic and therapeutic methods for applying these novel BGS-42 polypeptides to the diagnosis, treatment, and/or prevention of various diseases and/or disorders related to these polypeptides. The invention further relates to screening methods for identifying agonists and antagonists of the polynucleotides and polypeptides of the present invention.
    Type: Application
    Filed: September 10, 2007
    Publication date: January 31, 2008
    Inventors: John Feder, Shujian Wu, Thomas Nelson, Liana Lee
  • Metalloprotease highly expressed in the testis, MMP-29
    Patent number: 7285633
    Abstract: The present invention provides novel polynucleotides encoding MMP-29 polypeptides, fragments and homologues thereof. Also provided are vectors, host cells, antibodies, and recombinant and synthetic methods for producing said polypeptides. The invention further relates to diagnostic and therapeutic methods for applying these novel MMP-29 polypeptides to the diagnosis, treatment, and/or prevention of various diseases and/or disorders related to these polypeptides. The invention further relates to screening methods for identifying agonists and antagonists of the polynucleotides and polypeptides of the present invention.
    Type: Grant
    Filed: December 21, 2005
    Date of Patent: October 23, 2007
    Assignee: Bristol-Myers Squibb Company
    Inventors: Shujian Wu, Jian Chen, John N. Feder, Liana Lee, Stanley R. Krystek
  • Polynucleotides encoding three novel human cell surface proteins with leucine rich repeats and immunoglobulin folds, BGS2, 3 and 4 and variants thereof
    Publication number: 20070178088
    Abstract: The present invention provides novel polynucleotides encoding BGS-2, 3, and 4 polypeptides, fragments and homologues thereof Also provided are vectors, host cells, antibodies, and recombinant and synthetic methods for producing said polypeptides. The invention further relates to diagnostic and therapeutic methods for applying these novel BGS-2, 3, and 4 polypeptides to the diagnosis, treatment, and/or prevention of various diseases and/or disorders related to these polypeptides. The invention further relates to screening methods for identifying agonists and antagonists of the polynucleotides and polypeptides of the present invention.
    Type: Application
    Filed: March 21, 2007
    Publication date: August 2, 2007
    Inventors: Shujian Wu, Stanley Krystek, Liana Lee, John Feder, Janet Cheng
  • Polynucleotide encoding a novel TRP channel family member, TRP-PLIK2, and splice variants thereof
    Publication number: 20070172880
    Abstract: The present invention provides novel polynucleotides encoding TRP-PLIK2 polypeptides, fragments and homologues thereof. The present invention also provides polynucleotides encoding variants and splice variants of TRP-PLIK2 polypeptides, TRP-PLIK2b, TRP-PLIK2c, and TRP-PLIK2d, respectively. Also provided are vectors, host cells, antibodies, and recombinant and synthetic methods for producing said polypeptides. The invention further relates to diagnostic and therapeutic methods for applying these novel TRP-PLIK2, TRP-PLIK2b, TRP-PLIK2c, and TRP-PLIK2d polypeptides to the diagnosis, treatment, and/or prevention of various diseases and/or disorders related to these polypeptides. The invention further relates to screening methods for identifying agonists and antagonists of the polynucleotides and polypeptides of the present invention.
    Type: Application
    Filed: March 21, 2007
    Publication date: July 26, 2007
    Inventors: Ning Lee, Jian Chen, John Feder, Shujian Wu, Han Chang, Liana Lee, Michael Blanar, David Bol
  • Polynucleotides encoding three novel human cell surface proteins with leucine rich repeats and immunologobulin folds, BGS2, 3, and 4 and variants thereof
    Patent number: 7223558
    Abstract: The present invention provides novel polynucleotides encoding BGS-2, 3, and 4 polypeptides, fragments and homologues thereof. Also provided are vectors, host cells, antibodies, and recombinant and synthetic methods for producing said polypeptides. The invention further relates to diagnostic and therapeutic methods for applying these novel BGS-2, 3, and 4 polypeptides to the diagnosis, treatment, and/or prevention of various diseases and/or disorders related to these polypeptides. The invention further relates to screening methods for identifying agonists and antagonists of the polynucleotides and polypeptides of the present invention.
    Type: Grant
    Filed: July 11, 2002
    Date of Patent: May 29, 2007
    Assignee: Bristol-Myers Squibb Company
    Inventors: Shujian Wu, Stanley R. Krystek, Liana Lee, John N. Feder, Janet D. Cheng
  • Novel human cell surface protein with immunoglobulin folds, BGS-19
    Publication number: 20070071743
    Abstract: The present invention provides novel polynucleotides encoding BGS-19 polypeptides, fragments and homologues thereof. Also provided are vectors, host cells, antibodies, and recombinant and synthetic methods for producing said polypeptides. The invention further relates to diagnostic and therapeutic methods for applying the novel BGS-19 polypeptides to the diagnosis, treatment, and/or prevention of various diseases and/or disorders related to these polypeptides. The invention further relates to screening methods for identifying agonists and antagonists of the polynucleotides and polypeptides of the present invention.
    Type: Application
    Filed: November 17, 2006
    Publication date: March 29, 2007
    Inventors: Liana Lee, John Feder, Shujian Wu, Jian Chen
  • Polynucleotides encoding the novel human phosphatase, RET31, and variants thereof
    Patent number: 7153678
    Abstract: The present invention provides novel polynucleotides encoding human phosphatase polypeptides, fragments and homologues thereof. Also provided are vectors, host cells, antibodies, and recombinant and synthetic methods for producing said polypeptides. The invention further relates to diagnostic and therapeutic methods for applying these novel human phosphatase polypeptides to the diagnosis, treatment, and/or prevention of various diseases and/or disorders related to these polypeptides, particularly cardiovascular diseases and/or disorders. The invention further relates to screening methods for identifying agonists and antagonists of the polynucleotides and polypeptides of the present invention.
    Type: Grant
    Filed: December 20, 2001
    Date of Patent: December 26, 2006
    Assignee: Bristol-Myers Squibb
    Inventors: Donald G. Jackson, Chandra S. Ramanathan, John N. Feder, Liana Lee, Thomas C. Nelson, Nathan Siemers, Suzanne J. Suchard, Joshua Finger, C. Gordon Todderud, Dana Banas
  • Polynucleotides encoding a novel glycine receptor alpha subunit expressed in the gastrointestinal tract, HGRA4, and splice variant thereof
    Patent number: 7056737
    Abstract: The present invention provides novel polynucleotides encoding HGRA4 polypeptides, fragments and homologues thereof. The present invention also provides novel polynucleotides encoding a HGRA4 splice variant, HGRA4sv. Also provided are vectors, host cells, antibodies, and recombinant and synthetic methods for producing said polypeptides. The invention further relates to diagnostic and therapeutic methods for applying these novel HGRA4 and HGRA4sv polypeptides to the diagnosis, treatment, and/or prevention of various diseases and/or disorders related to these polypeptides. The invention further relates to screening methods for identifying agonists and antagonists of the polynucleotides and polypeptides of the present invention.
    Type: Grant
    Filed: February 13, 2002
    Date of Patent: June 6, 2006
    Assignee: Bristol-Myers Squibb Company
    Inventors: John N. Feder, Liana Lee, Jian Chen, Nathan O. Siemers, Han Chang
  • Polynucleotide encoding a novel metalloprotease highly expressed in the testis, MMP-29
    Publication number: 20060105379
    Abstract: The present invention provides novel polynucleotides encoding MMP-29 polypeptides, fragments and homologues thereof. Also provided are vectors, host cells, antibodies, and recombinant and synthetic methods for producing said polypeptides. The invention further relates to diagnostic and therapeutic methods for applying these novel MMP-29 polypeptides to the diagnosis, treatment, and/or prevention of various diseases and/or disorders related to these polypeptides. The invention further relates to screening methods for identifying agonists and antagonists of the polynucleotides and polypeptides of the present invention.
    Type: Application
    Filed: December 21, 2005
    Publication date: May 18, 2006
    Inventors: Shujian Wu, Jian Chen, John Feder, Liana Lee, Stanley Krystek
  • Human phosphatase RET31, and variants thereof
    Publication number: 20060014180
    Abstract: The present invention provides novel polynucleotides encoding human phosphatase polypeptides, fragments and homologues thereof. Also provided are vectors, host cells, antibodies, and recombinant and synthetic methods for producing said polypeptides. The invention further relates to diagnostic and therapeutic methods for applying these novel human phosphatase polypeptides to the diagnosis, treatment, and/or prevention of various diseases and/or disorders related to these polypeptides, particularly cardiovascular diseases and/or disorders. The invention further relates to screening methods for identifying agonists and antagonists of the polynucleotides and polypeptides of the present invention.
    Type: Application
    Filed: June 2, 2005
    Publication date: January 19, 2006
    Inventors: Donald Jackson, Chandra Ramanathan, John Feder, Gabe Mintier, Liana Lee, Thomas Nelson, Nathan Siemers, David Bol, Suzanne Suchard, Gary Schieven, Joshua Finger, C. Todderrud, Donna Bassolino, Stanley Krystek, Dana Banas, Patrick McAtee
  • POLYNUCLEOTIDES ENCODING NOVEL HUMAN PHOSPHATASES
    Publication number: 20050130286
    Abstract: The present invention provides novel polynucleotides encoding human phosphatase polypeptides, fragments and homologues thereof. Also provided are vectors, host cells, antibodies, and recombinant and synthetic methods for producing said polypeptides. The invention further relates to diagnostic and therapeutic methods for applying these novel human phosphatase polypeptides to the diagnosis, treatment, and/or prevention of various diseases and/or disorders related to these polypeptides, particularly cardiovascular diseases and/or disorders. The invention further relates to screening methods for identifying agonists and antagonists of the polynucleotides and polypeptides of the present invention.
    Type: Application
    Filed: December 20, 2001
    Publication date: June 16, 2005
    Inventors: Donald Jackson, Chandra Ramanathan, John Feder, Gabe Mintier, Liana Lee, Thomas Nelson, Nathan Siemers, David Bol, Suzanne Suchard, Gary Schieven, Joshua Finger, C. Todderrud, Donna Bassolino, Stanley Krystek, Dana Banas, Patrick McAtee
  • Polynucleotides encoding three novel human cell surface proteins with leucine rich repeats and immunologobulin folds, BGS2, 3, and 4 and variants thereof
    Publication number: 20030195163
    Abstract: The present invention provides novel polynucleotides encoding BGS-2, 3, and 4 polypeptides, fragments and homologues thereof. Also provided are vectors, host cells, antibodies, and recombinant and synthetic methods for producing said polypeptides. The invention further relates to diagnostic and therapeutic methods for applying these novel BGS-2, 3, and 4 polypeptides to the diagnosis, treatment, and/or prevention of various diseases and/or disorders related to these polypeptides. The invention further relates to screening methods for identifying agonists and antagonists of the polynucleotides and polypeptides of the present invention.
    Type: Application
    Filed: July 11, 2002
    Publication date: October 16, 2003
    Inventors: Shujian Wu, Stanley R. Krystek, Liana Lee, John N. Feder, Janet D. Cheng
  • Polynucleotide encoding a novel TRP channel family member, LTRPC3, and splice variants thereof
    Publication number: 20030162189
    Abstract: The present invention provides novel polynucleotides encoding LTRPC3 polypeptides, fragments and homologues thereof. The present invention also provides polynucleotides encoding variants and splice variants of LTRPC3 polypeptides, LTRPC3b, LTRPC3c, LTRPC3d, LTRPC3e, and LTRPC3f, respectively. Also provided are vectors, host cells, antibodies, and recombinant and synthetic methods for producing said polypeptides. The invention further relates to diagnostic and therapeutic methods for applying these novel LTRPC3, LTRPC3b, LTRPC3c, LTRPC3d, LTRPC3e, and LTRPC3f polypeptides to the diagnosis, treatment, and/or prevention of various diseases and/or disorders related to these polypeptides. The invention further relates to screening methods for identifying agonists and antagonists of the polynucleotides and polypeptides of the present invention.
    Type: Application
    Filed: August 1, 2002
    Publication date: August 28, 2003
    Inventors: Ning Lee, Jian Chen, John Feder, Shujian Wu, Liana Lee, Michael A. Blanar, David Bol, Paul C. Levesque, Lucy Sun
  • Polynucleotide encoding a novel human potassium channel alpha-subunit, K+alphaM2
    Publication number: 20030152953
    Abstract: The present invention provides novel polynucleotides encoding K+alphaM2 polypeptides, fragments and homologues thereof. Also provided are vectors, host cells, antibodies, and recombinant and synthetic methods for producing said polypeptides. The invention further relates to diagnostic and therapeutic methods for applying these novel K+alphaM2 polypeptides to the diagnosis, treatment, and/or prevention of various diseases and/or disorders related to these polypeptides. The invention further relates to screening methods for identifying agonists and antagonists of the polynucleotides and polypeptides of the present invention.
    Type: Application
    Filed: July 19, 2002
    Publication date: August 14, 2003
    Inventors: John N. Feder, Liana Lee, Han Chang
  • Polynucleotide encoding a novel TRP channel family member, TRP-PLIK2, and splice variants thereof
    Publication number: 20030144191
    Abstract: The present invention provides novel polynucleotides encoding TRP-PLIK2 polypeptides, fragments and homologues thereof. The present invention also provides polynucleotides encoding variants and splice variants of TRP-PLIK2 polypeptides, TRP-PLIK2b, TRP-PLIK2c, and TRP-PLIK2d, respectively. Also provided are vectors, host cells, antibodies, and recombinant and synthetic methods for producing said polypeptides. The invention further relates to diagnostic and therapeutic methods for applying these novel TRP-PLIK2, TRP-PLIK2b, TRP-PLIK2c, and TRP-PLIK2d polypeptides to the diagnosis, treatment, and/or prevention of various diseases and/or disorders related to these polypeptides. The invention further relates to screening methods for identifying agonists and antagonists of the polynucleotides and polypeptides of the present invention.
    Type: Application
    Filed: May 22, 2002
    Publication date: July 31, 2003
    Inventors: Ning Lee, Jian Chen, John N. Feder, Shujian Wu, Han Chang, Liana Lee, Michael A. Blanar, David Bol
  • Polynucleotide encoding a novel potassium channel with homology to the ether-a-go-go family, HEAG2
    Publication number: 20030114354
    Abstract: The present invention provides novel polynucleotides encoding HEAG2 polypeptides, fragments and homologues thereof. Also provided are vectors, host cells, antibodies, and recombinant and synthetic methods for producing said polypeptides. The invention further relates to diagnostic and therapeutic methods for applying these novel HEAG2 polypeptides to the diagnosis, treatment, and/or prevention of various diseases and/or disorders related to these polypeptides. The invention further relates to screening methods for identifying agonists and antagonists of the polynucleotides and polypeptides of the present invention.
    Type: Application
    Filed: June 19, 2002
    Publication date: June 19, 2003
    Inventors: John N. Feder, Liana Lee, Jian Chen, Donald Jackson, Chandra S. Ramanathan, Nathan O. Siemers, Han Chang, Franck Duclos, Stanley R. Krystek
  • Polynucleotide encoding a novel human potassium channel beta-subunit, K+betaM3
    Publication number: 20030114371
    Abstract: The present invention provides novel polynucleotides encoding K+betaM3 polypeptides, fragments and homologues thereof. Also provided are vectors, host cells, antibodies, and recombinant and synthetic methods for producing said polypeptides. The invention further relates to diagnostic and therapeutic methods for applying these novel K+betaM3 polypeptides to the diagnosis, treatment, and/or prevention of various diseases and/or disorders related to these polypeptides. The invention further relates to screening methods for identifying agonists and antagonists of the polynucleotides and polypeptides of the present invention.
    Type: Application
    Filed: February 7, 2002
    Publication date: June 19, 2003
    Inventors: John N. Feder, Liana Lee, Jian Chen, Donald Jackson, Chandra S. Ramanathan, Nathan O. Siemers, Han Chang, Rolf-Peter Ryseck, Andrew J. Watson, Pamela Carroll
  • Polynucleotide encoding a novel metalloprotease highly expressed in the testis, MMP-29
    Publication number: 20030109021
    Abstract: The present invention provides novel polynucleotides encoding MMP-29 polypeptides, fragments and homologues thereof. Also provided are vectors, host cells, antibodies, and recombinant and synthetic methods for producing said polypeptides. The invention further relates to diagnostic and therapeutic methods for applying these novel MMP-29 polypeptides to the diagnosis, treatment, and/or prevention of various diseases and/or disorders related to these polypeptides. The invention further relates to screening methods for identifying agonists and antagonists of the polynucleotides and polypeptides of the present invention.
    Type: Application
    Filed: April 26, 2002
    Publication date: June 12, 2003
    Inventors: Shujian Wu, Jian Chen, John N. Feder, Liana Lee, Stanley R. Krystek