Patents by Inventor Liandi CHEN

Liandi CHEN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • BISPECIFIC ANTIBODY AGAINST CCR8 AND CTLA4
    Publication number: 20260234261
    Abstract: An antibody or an antigen-binding fragment thereof and a single-domain antibody or an antigen-binding fragment thereof that can specifically bind to CTLA4, and an immunoconjugate, a pharmaceutical composition and a multispecific molecule comprising the antibody or the antigen-binding fragment thereof. Furthermore, the present invention also relates to a multispecific molecule that can specifically bind to CCR8 and CTLA4 and the use thereof.
    Type: Application
    Filed: April 16, 2026
    Publication date: August 13, 2026
    Inventors: Liandi Chen, Yi Luo, Xiaoniu Miao, Tianhang Zhai, Weifeng Huang, Andy Tsun
  • ANTI-SERUM ALBUMIN NANOBODY AND DERIVATIVE THEREOF
    Publication number: 20250223340
    Abstract: The present invention relates to a nanobody or antigen-binding fragment thereof that specifically binds to serum albumin, a derivative comprising the nanobody or the antigen-binding fragment thereof, a nucleic acid encoding the antibody or antigen-binding fragment thereof, a host cell comprising same, and related uses. Further, the present invention relates to therapeutic use of the antibody or the antigen-binding fragment thereof or the derivative.
    Type: Application
    Filed: March 31, 2023
    Publication date: July 10, 2025
    Inventors: Fan WU, Xiaoniu MIAO, Yi LUO, Liandi CHEN, Yingda XU
  • Anti-CEACAM5 monoclonal antibody and preparation method thereof and use thereof
    Publication number: 20220242968
    Abstract: Disclosed are a monoclonal antibody and antigen-binding fragment thereof which can specifically bind to human carcinoembryonic antigen-related cell adhesion molecule 5 (CEACAM5); also disclosed is a chimeric antigen receptor based on said antibody, and a method for preparing said antibody and antigen-binding fragment and use thereof for treating CEACAM5-related tumors.
    Type: Application
    Filed: June 3, 2020
    Publication date: August 4, 2022
    Applicant: BIOTHEUS INC.
    Inventors: Shifu MO, Wei XU, Yi LUO, Liandi CHEN