Abstract: The present invention provides a compound of formula I: a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.

Abstract: The present invention provides a compound of formula I: a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.

Abstract: Business application logic corresponding to a business is generated according to requirements of the business. The business application logic includes Web services and Widgets. The Widgets in the business application logic are mashed up to create a Widget mashup application. An adaptation relationship is established between the Web services and the Widgets in the Widget mashup application. An executable business process is generated for the business based on the business application logic and the adaptation relationship. An executable mashup Widget application is generated based on the Widget mashup application and the adaptation relationship.

Abstract: Methods and systems for data management are disclosed. With embodiments of the present disclosure, data files originating from the same source data can be de-duplicated. One such method comprises calculating one or more of a first characteristic value for first data in a first format, and one or more second characteristic values for one or more data in one or more second formats into which the first data can be converted, said characteristic value uniquely representing an arrangement characteristic of at least part of bits of data in a particular format. The method also includes storing one of the first data and the second data in response to one of the calculated characteristic values being the same as a stored characteristic value corresponding to a second data.

Abstract: Instance documents related to policy enforcement are gathered according to a business requirement. The instance documents are instantiated from corresponding schema documents. An instantiated context model, including references to the gathered instance documents, is generated from a context model definition. A policy set to be enforced using the instantiated context model is generated according to the gathered instance documents. An enforcement sequence of policies in the policy set is determined. The policies are applied to the instantiated context model according to the enforcement sequence.

Abstract: In some examples, solid oxide fuel cell system comprising a solid oxide fuel cell including an anode, an anode conductor layer, a cathode, a cathode conductor layer, and electrolyte, wherein the anode and the anode conductor layer each comprise nickel; and a sacrificial nickel source separate from that of the anode and anode conductor layer, wherein the sacrificial nickel source is configured to reduce the loss or migration of the nickel of the anode and/or the anode current collector in the fuel cell during operation

Abstract: A method for enforcing context model based Service-Oriented Architecture (SOA) policies is provided, which includes: gathering instance documents related to policy enforcement according to a business requirement; generating an instantiated context model using the gathered instance documents; generating a policy set to be enforced according to the gathered instance documents; determining an enforcement sequence of policies in the policy set; and applying the policies to the instantiated context model according to the enforcement sequence. The method for enforcing context model based SOA policies may flexibly gather the instance documents according to scenarios and purposes of the policy enforcement to define the policy scope, such as project, application, service, etc., and may be applied to various types of the SOA policies. In addition, a policy engine for enforcing context model based SOA policies is provided.

Abstract: The teachings provided herein generally relate to compositions comprising rutaecarpine derivatives that activates CYP1A2 through enzyme induction. The uses for such a derivative can include removing caffeine from a subject, improving sleep, treating insomnia, treating caffeine toxicity, treating caffeine addiction and withdrawal symptoms, and the like. Caffeine is just one example of a substrate that can be removed using the derivatives taught herein, and other examples, including theophylline, are provided herein.

Abstract: A system includes a first feedpoint and a second feedpoint symmetrically disposed on the left and right sides of an antenna on a small board. A first switch, a second switch, and a third switch are disposed on a mainboard. The first switch, the second switch, and the third switch are controlled through a control instruction so that the system is in a first connection state and a second connection state. Signal strength corresponding to the first connection state and signal strength corresponding to the second connection state are detected, and if the signal strength corresponding to the first connection state is greater than the signal strength corresponding to the second connection state, each switch is controlled through an instruction so that the system is in the first connection state, in which the first feedpoint is working. Otherwise, the second feedpoint is working.

Abstract: The teachings provided herein generally relate to compositions comprising a rutaecarpine derivative that activates CYP1A2 through enzyme induction. The uses for such a derivative, in some embodiments can include improving sleep, as well as treating insomnia. Other uses for the derivatives are provided herein.

Abstract: The teachings provided herein generally relate to compositions comprising rutaecarpine derivatives that activates CYP1A2 through enzyme induction. The uses for such a derivative can include removing caffeine from a subject, improving sleep, treating insomnia, treating caffeine toxicity, treating caffeine addiction and withdrawal symptoms, and the like. Caffeine is just one example of a substrate that can be removed using the derivatives taught herein, and other examples, including theophylline, are provided herein.

Abstract: The teachings provided herein generally relate to compositions comprising a rutaecarpine derivative that activates CYP1A2 through enzyme induction. The compound can be used for treating caffeine toxicity, in some embodiments. Caffeine is just one example of a substrate that can be removed using the derivatives taught herein, and other examples, including theophylline, are provided herein.

Abstract: Business application logic corresponding to a business is generated according to requirements of the business. The business application logic includes Web services and Widgets. The Widgets in the business application logic are mashed up to create a Widget mashup application. An adaptation relationship is established between the Web services and the Widgets in the Widget mashup application. An executable business process is generated for the business based on the business application logic and the adaptation relationship. An executable mashup Widget application is generated based on the Widget mashup application and the adaptation relationship.

Abstract: Exemplary embodiments provide tunable laser devices, methods for making the laser devices and methods for tuning the laser devices. The tunable laser devices can include an optically pumped semiconductor laser heterostructure, on which a distributed-feedback (DFB) laser grating having variable grating spacings (or chirps) can be formed. The optically pumped semiconductor laser heterostructure can be an optically pumped type-II quantum well laser structure. The emission wavelength of the tunable laser devices can be tuned by changing positions of the region illuminated by the pump laser and with respect to the chirped DFB grating. The disclosed laser devices and methods can provide tunable laser emission with a combination of narrow linewidth and high output power that can be used for remote sensing applications and/or spectroscopic applications across the entire mid infrared (IR) spectral region.

Abstract: At least one XML document to be validated is parsed, and XML data in the at least one XML document is represented as data objects in at least one data object model in a memory. At least one rule document is parsed and a rule object model is created in the memory. At least part of the data objects are extracted from the at least one data object model and at least part of rule objects are extracted from the rule object model. Validation is performed in a corresponding execution context for the extracted at least part of the data objects based upon the extracted at least part of the rule objects.

Abstract: A method for enforcing a number of context model based policies with forward chaining comprising applying a policy set including a plurality of policies to an instantiated context model which includes a set of referenced instance documents in XML format, determining whether the instantiated context model should be updated, if the instantiated context model should be updated, executing an updating operation, re-generating a new instantiated context model according to the updated instance documents and the instantiated context model, and applying the policy set to the new instantiated context model, and wherein the policies include a condition part and an action part.

Abstract: A method for enforcing context model based Service-Oriented Architecture (SOA) policies is provided, which includes: gathering instance documents related to policy enforcement according to a business requirement; generating an instantiated context model using the gathered instance documents; generating a policy set to be enforced according to the gathered instance documents; determining an enforcement sequence of policies in the policy set; and applying the policies to the instantiated context model according to the enforcement sequence. The method for enforcing context model based SOA policies may flexibly gather the instance documents according to scenarios and purposes of the policy enforcement to define the policy scope, such as project, application, service, etc., and may be applied to various types of the SOA policies. In addition, a policy engine for enforcing context model based SOA policies is provided.

Abstract: A sealant composition for use in sealing solid oxide fuel cells is provided which comprises a glass component which comprises a mixture of alkali-free inorganic oxides, and an optional filler component dispersed in the glass component, said filler component being up to 40% by weight of the composition. The glass component can include, on a mole basis, 20 to 50% BaO, 1 to 10% Y2O3, 5 to 20% B2O3, 10 to 30% SiO2, 3 to 35% MgO, 2 to 20% CaO, 1 to 10% ZnO, and 0 to 5% ZrO2, and exemplary filler components include zirconia, alumina, barium titanate, strontium titanate, and combinations thereof.

Abstract: Exemplary embodiments provide tunable laser devices, methods for making the laser devices and methods for tuning the laser devices. The tunable laser devices can include an optically pumped semiconductor laser heterostructure, on which a distributed-feedback (DFB) laser grating having variable grating spacings (or chirps) can be formed. The optically pumped semiconductor laser heterostructure can be an optically pumped type-II quantum well laser structure. The emission wavelength of the tunable laser devices can be tuned by changing positions of the region illuminated by the pump laser and with respect to the chirped DFB grating. The disclosed laser devices and methods can provide tunable laser emission with a combination of narrow linewidth and high output power that can be used for remote sensing applications and/or spectroscopic applications across the entire mid infrared (IR) spectral region.

Abstract: Described are methods, systems, and apparatus, including computer program products for determining material constitutive relationships of fracture in a ductile material undergoing plastic deformation. A material pressure function is determined that describes dependence of a damage rule of at least a portion of the ductile material on pressure. A material azimuthal angle function is determined that describes dependence of the damage rule of the portion of the ductile material on principle stress. The damage rule of the portion of the ductile material is determined based on the material pressure function and the material azimuthal angle function. A weakening function of the portion of the ductile material is determined based on the damage rule. Material constitutive relationships of fracture in the portion of the ductile material are determined based on the weakening function and a matrix property of the ductile material.