Abstract: A molecule representation is extracted from a document and associated with the document in a metadata database. For example, an image of a molecular structure may be extracted from a document and stored in the metadata database in a text-based representation such as SMILES. The metadata database may be searched to identify documents that mention a particular molecule. Continuing the example, the metadata database may be searched with a SMILES representation to identify the document and other documents that refer to the same molecule. The metadata database may index documents based on different types of molecule representations, including text-based, image-based, graph-based, name, abbreviation, etc. This allows search over multiple representations of a molecule, improving accuracy and thoroughness. These improvements reduce the time and computational resources needed to search for documents that refer to a particular molecule.

Abstract: The various implementations described herein include methods and systems for coding video. In one aspect, a method includes receiving a video bitstream comprising a set of encoded video information and a first indicator associated with a plurality of probability models. The method includes determining a value of the first indicator by parsing the video bitstream. The method includes, when the first indicator has a first value, selecting a first probability model from the plurality of probability models and when the first indicator has a second value, selecting a second probability model from the plurality of probability models, the second probability model being different from the first probability model. The method also includes entropy decoding the set of encoded video information using the selected probability model.

Abstract: A device and a method for steering a vehicle are provided. The method includes following steps: obtaining a point cloud data of a vehicle through a lidar, obtaining an RGB image of the vehicle through a camera, and obtaining a current speed of the vehicle through a wheel speed sensor; using the current speed and local path way points associated with the point cloud data to obtain a target angle; using the current speed and a central lane distance error associated with the RGB image to obtain a compensator angle; and using the target angle and the compensator angle to obtain a steering command, and steering the vehicle to drive in a lane according to the steering command.

Abstract: A fibroblast activation protein (FAP) compound or salt is provided with albumin dual-binding function. It is a new target FAP molecule, comprising a payload group, a linker group and a FAP binding group. The linker group has an architecture selected from four architectures to connect to the payload group and the FAP binding group to form the FAP compound. The target FAP molecule has the biological activity of binding to albumin in blood and that of binding to FAP protein. The present invention is combined with radioactive nuclide Lu-177, Ac-225, Ga-67 or In-111 for long-circulation FAP targeting in the body. Higher accumulation in expressing FAP tumors is achieved, and the accumulation time of inhibitors in tumors is prolonged. The present invention allows radioactivity to act in the tumor for a long time, thereby reducing the radioactivity concentration or reducing the frequency of radioactive inhibitor administration to inhibit tumor growth.

Abstract: A multi-mode switching simulation training system based on a real centralized traffic control (CTC) system, including a center platform and a plurality of student platforms connected to the center platform through a network, where the center platform includes a first management module and a first training system connected to the first management module; each student platform includes a second management module and a second training system connected to the second management module; and the first management module is configured to control the start and stop of the first training system, and the second management module is configured to control the start and stop of the second training system, so as to switch a training mode of the multi-mode switching simulation system. The present invention can achieve the purposes of individual training for dispatchers, individual training for attendants, joint training for the dispatchers and the attendants, and skills competition.

Abstract: A bidirectional on-board charger includes a direct current bus, two bus capacitors, a power factor correction circuit, and a controller. The power factor correction circuit includes: a first bridge arm; and three second bridge arms, separately connected in series between the positive electrode and the negative electrode of the direct current bus. The controller is configured to: control the first switch (K1) to be turned off, and control at least one of the second bridge arms to output a direct current to charge a power battery; or control the first switch (K1) to be turned on, and control a midpoint of at least one of the second bridge arms to output an alternating current to supply power to an alternating current load. A Vehicle power system and an electric vehicle are further disclosed. The charger reduces circuit costs.

Abstract: A vehicle comprises a front longitudinal beam, a subframe and a subframe front mounting point, wherein the subframe front mounting point is connected to the front longitudinal beam, the subframe front mounting point is arranged on the outside of the front longitudinal beam in the widthwise direction of the vehicle, and the subframe is connected to the front longitudinal beam by means of the subframe front mounting point.

Abstract: A reactor system may comprise a moving bed reactor, a fluidized bed reactor, and a separation unit. The moving bed reactor may comprise catalyst material particles comprising a metal oxide support and a transition metal alloy, where the transition metal alloy comprises two transition metal elements. The moving bed reactor may comprise an inlet configured to receive a hydrocarbon and an outlet configured to provide hydrogen (H2) generated within the moving bed reactor. The fluidized bed reactor may be in fluid communication with the moving bed reactor and configured to receive the catalyst material particles and deposited carbon material from the moving bed reactor. The separation unit may be in fluid communication with an outlet of the fluidized bed reactor and configured to separate the catalyst material particles from carbon material and inert gas. The separation unit may be in fluid communication with the moving bed reactor.

Abstract: Provided are a human LIFR antigen binding protein, a preparation method therefor, and an application thereof. A series of human LIFR antibodies having biological functions are obtained using human LIFR-ECD protein immune H2L2 humanized antibody transgenic mice by means of single B cell cloning technology (SBC), single B cell sequencing analysis, and Fc recombination. The method greatly improves the discovery efficiency and the yield of antibody drugs, and the obtained human LIFR antibody has good affinity and can block the binding of huLIF proteins to huLIFR/gp130 cells, thereby inhibiting signaling pathways such as STAT3, further inhibiting the growth of tumors, and achieving the purpose of tumor prevention and treatment.

Abstract: Provided are a hydantoin compound as represented by formula (I) or a pharmaceutically acceptable salt thereof and the medical use thereof. The compound has a strong agonistic action on PPAR? and PPAR?, has a good selectivity to PPAR?, and has good pharmacokinetic properties. The compound or a pharmaceutically acceptable salt, prodrug, deuterated compound or solvate thereof can be used for preparing a PPAR?/? dual agonist, and is used for preparing a drug for preventing or treating diseases mediated by PPAR? and/or PPAR?.

Abstract: The present invention relates to a novel antibody, an antigen-binding fragment thereof and the uses of the antibody and fragment, wherein the antibody and the fragment comprise specific complementarity-determining regions (CDRs) and/or specifically bind to human CD73 at specific epitopes.

Abstract: A lens for a lamp. The lens comprises a front or light-exiting surface, a reflective or side surface and a light incident or light receiving surface. The front surface comprises a portion that defines a stepped-shape cavity that extends into the lens. Part of the light that travels from the light incident surface to the portion of the front surface (defining the stepped-shape cavity) is transmitted, and another part is reflected towards the reflective surface. Light that travels from the light incident surface or the portion of the front surface (defining the stepped-shape cavity) to the reflective surface is redirected towards the front surface and out of the lens.

Abstract: The present invention is directed to triple combination therapies with anti-TIGIT antibodies, anti-PVRIG antibodies, and checkpoint inhibitors, including anti-PD-1 or anti-PD-L1 antibodies.

Abstract: A multi-battery-equipped robot includes a casing assembly, a control box provided within the casing assembly, a driving motor, a suction motor and at least two battery assemblies. The driving motor is detachably provided on an inner wall of the casing assembly. The suction motor is detachably provided on an inner bottom surface of the casing assembly. Each battery assembly includes a battery pack and a circuit board. An outer wall of the casing assembly is provided with a slot, in which the battery assemblies are detachably provided. The battery pack is electrically connected to the circuit board through a first cable. The circuit board is electrically connected to the control box through a second cable. Any two circuit boards are electrically connected to each other through a third cable.

Abstract: Provided are a waterborne polyurethane (WPU) and a preparation method thereof, and a waterborne scratch-off ink and a preparation method thereof. A chain end group or side group of the WPU contains a longer alkyl chain. When the WPU is used in the preparation of the waterborne scratch-off ink, microphase separation may occur during the film-forming process owing to a hydrophobic/hydrophilic interaction between the non-polar long-chain alkyl and polar groups in WPU molecular, resulting in an incomplete film structure, which is beneficial to make the ink be scratched off.

Abstract: A coupled lens structure for a mixed/augmented reality system includes: a lens tube; a first lens with a first aspherical light input surface coupled to a lens-tube light input surface; a second lens with a second spherical light input surface optically coupled to a first spherical light output surface of the first lens; a third lens with a third spherical light input surface optically coupled to a second aspherical light output surface of the second lens; and a fourth lens with a fourth spherical light input surface optically coupled to a third spherical light output surface of the third lens and a fourth spherical light output surface coupled to a lens-tube light output surface. The coupled lens structure has volume of 2.1-3 cc, a lens-tube outer diameter of 12-13.5 mm, and a full angle of view not greater than 30 degrees, featuring an effective reduction in volume and weight.

Abstract: The present application relates to a method for in vitro induction and expansion of high-purity and high-cytotoxic NK cells. The method includes: inoculating isolated mononuclear cells in a pre-coated culture flask or a culture dish for culture treatment; and performing activation and induction culture in a culture medium containing monoclonal antibodies and cytokines, to finally obtain NK cells. The coating is performed in a buffer containing anti-CD16 monoclonal antibody and IL-21.

Abstract: A detection system and a sample processing instrument for nanoparticles are provided. The detection system includes a light emitting unit and a light collection unit. The light emitting unit is configured to emit a light beam and project the light beam onto a nanoparticle to be detected. The light collection unit is configured to collect light beams from the nanoparticle so as to analyze the nanoparticles according to the collected light beams. The light emitting unit includes multiple light sources and a focusing lens, and the light beams emitted by the multiple light sources are focused through the focusing lens on a same detection position through which the nanoparticle is to pass.

Abstract: Disclosed herein is generally directed to antibodies against the Siglec-3, and pharmaceutical compositions that comprise the antibodies. According to some embodiments of the present disclosure, the present anti-Siglec-3 antibodies may suppress the over activation of Siglec-3, thereby reversing the immunosuppression effects resulted therefrom. As such, the present antibodies may treat diseases associated with the over activation of Siglec-3, such as hepatitis B virus (HBV) infection, neurodegenerative diseases, autoimmune diseases, or cancers. Accordingly, the present disclosure also includes methods for the treatment and/or prophylaxis of the above diseases.

Abstract: A projector includes a light source module, a light valve, and a projecting lens. The light source module includes a light-emitting element, a light diffusion assembly, a first structural component, and a first temperature-sensing element. The light-emitting element is adapted to emit an illumination light beam. The light diffusion assembly is adapted to diffuse the illumination light beam. The light diffusion assembly has a front end and a rear end opposite to each other, the front end of the light diffusion assembly faces the light-emitting element, and the rear end of the light diffusion assembly faces the first structural component. The first temperature-sensing element is disposed on the first structural component and corresponds to the light diffusion assembly. The light valve is adapted to convert the illumination light beam from the light source module into an image light beam. The projecting lens is adapted to project the image light beam.