Abstract: Included among the many structures described herein are photonic bandgap fibers designed to provide a desired dispersion spectrum. Additionally, designs for achieving wide transmission bands and lower transmission loss are also discussed. For example, in some fiber designs, smaller dimensions of high index material in the cladding and large core size provide small flat dispersion over a wide spectral range. In other examples, the thickness of the high index ring-shaped region closest to the core has sufficiently large dimensions to provide negative dispersion or zero dispersion at a desired wavelength. Additionally, low index cladding features distributed along concentric rings or circles may be used for achieving wide bandgaps.

Abstract: Various embodiments described herein include rare earth doped glass compositions that may be used in optical fiber and rods having large core sizes. Such optical fibers and rods may be employed in fiber lasers and amplifiers. The index of refraction of the glass may be substantially uniform and may be close to that of silica in some embodiments. Possible advantages to such features include reduction of formation of additional waveguides within the core, which becomes increasingly a problem with larger core sizes.

Abstract: Various types of holey fiber provide optical propagation. In various embodiments, for example, a large core holey fiber comprises a cladding region formed by large holes arranged in few layers. The number of layers or rows of holes about the large core can be used to coarse tune the leakage losses of the fundamental and higher modes of a signal, thereby allowing the non-fundamental modes to be substantially eliminated by leakage over a given length of fiber. Fine tuning of leakage losses can be performed by adjusting the hole dimension and/or the hole spacing to yield a desired operation with a desired leakage loss of the fundamental mode. Resulting holely fibers have a large hole dimension and spacing, and thus a large core, when compared to traditional fibers and conventional fibers that propagate a single mode. Other loss mechanisms, such as bend loss and modal spacing can be utilized for selected modes of operation of holey fibers. Other embodiments are also provided.

Abstract: One or more single mode few-moded or multimode fibers are incorporated into a bundle to carry input to a fiber amplifier or output from a fiber amplifier or a fiber laser. The input is at the signal wavelength, which is the wavelength where amplification or lasing occurs. Each of the fibers in the bundle is cleaved individually or as a group and fiber ends are aligned in the same plane. The fiber amplifier or fiber laser may include a double clad fiber and the other fibers of the bundle couple light for cladding pumping. The device may also include a mode filter for controlling the output mode.

Abstract: A variable-focus lens assembly is provided. The lens assembly includes a microfluidic device that defines a chamber for receiving a fluid therein. A slip having an aperture therethrough is disposed in the chamber. A first fluid is disposed on the first side of the slip and a second fluid is disposed on the second side of the slip. A lens is formed from the interface of the first and second fluids. The outer periphery is pinned to the slip about the aperture. A turning structure fabricated from a hydrogel material engages the slip and tunes the focal length of the lens in response to a predetermined stimulus.

Abstract: Various types of holey fiber provide optical propagation. In various embodiments, for example, a large core holey fiber comprises a cladding region formed by large holes arranged in few layers. The number of layers or rows of holes about the large core can be used to coarse tune the leakage losses of the fundamental and higher modes of a signal, thereby allowing the non-fundamental modes to be substantially eliminated by leakage over a given length of fiber. Fine tuning of leakage losses can be performed by adjusting the hole dimension and/or the hole spacing to yield a desired operation with a desired leakage loss of the fundamental mode. Resulting holey fibers have a large hole dimension and spacing, and thus a large core, when compared to traditional fibers and conventional fibers that propagate a single mode. Other loss mechanisms, such as bend loss and modal spacing can be utilized for selected modes of operation of holey fibers. Other embodiments are also provided.

Abstract: Included among the many structures described herein are photonic bandgap fibers designed to provide a desired dispersion spectrum. Additionally, designs for achieving wide transmission bands and lower transmission loss are also discussed. For example, in some fiber designs, smaller dimensions of high index material in the cladding and large core size provide small flat dispersion over a wide spectral range. In other examples, the thickness of the high index ring-shaped region closest to the core has sufficiently large dimensions to provide negative dispersion or zero dispersion at a desired wavelength. Additionally, low index cladding features distributed along concentric rings or circles may be used for achieving wide bandgaps.

Abstract: Included among the many structures described herein are photonic bandgap fibers designed to provide a desired dispersion spectrum. Additionally, designs for achieving wide transmission bands and lower transmission loss are also discussed. For example, in some fiber designs, smaller dimensions of high index material in the cladding and large core size provide small flat dispersion over a wide spectral range. In other examples, the thickness of the high index ring-shaped region closest to the core has sufficiently large dimensions to provide negative dispersion or zero dispersion at a desired wavelength. Additionally, low index cladding features distributed along concentric rings or circles may be used for achieving wide bandgaps.

Abstract: Various embodiments include large cores fibers that can propagate few modes or a single mode while introducing loss to higher order modes. Some of these fibers are holey fibers that comprising cladding features such as air-holes. Additional embodiments described herein include holey rods. The rods and fibers may be used in many optical systems including optical amplification systems, lasers, short pulse generators, Q-switched lasers, etc. and may be used for example for micromachining.

Abstract: Included among the many structures described herein are photonic bandgap fibers designed to provide a desired dispersion spectrum. Additionally, designs for achieving wide transmission bands and lower transmission loss are also discussed. For example, in some fiber designs, smaller dimensions of high index material in the cladding and large core size provide small flat dispersion over a wide spectral range. In other examples, the thickness of the high index ring-shaped region closest to the core has sufficiently large dimensions to provide negative dispersion or zero dispersion at a desired wavelength. Additionally, low index cladding features distributed along concentric rings or circles may be used for achieving wide bandgaps.

Abstract: One or more single mode few-moded or multimode fibers are incorporated into a bundle to carry input to a fiber amplifier or output from a fiber amplifier or a fiber laser. The input is at the signal wavelength, which is the wavelength where amplification or lasing occurs. Each of the fibers in the bundle is cleaved individually or as a group and fiber ends are aligned in the same plane. The fiber amplifier or fiber laser may include a double clad fiber and the other fibers of the bundle couple light for cladding pumping. The device may also include a mode filter for controlling the output mode.

Abstract: One or more single mode few-moded or multimode fibers are incorporated into a bundle to carry input to a fiber amplifier or output from a fiber amplifier or a fiber laser. The input is at the signal wavelength, which is the wavelength where amplification or lasing occurs. Each of the fibers in the bundle is cleaved individually or as a group and fiber ends are aligned in the same plane. The fiber amplifier or fiber laser may include a double clad fiber and the other fibers of the bundle couple light for cladding pumping. The device may also include a mode filter for controlling the output mode.

Abstract: A controlled release dosage form includes an active agent composition and a squeeze layer circumscribing at least a portion of the active agent composition. The squeeze layer includes a material that changes shape in a selected fluid environment of use. The material when it changes shape applies a squeeze force to the active agent composition.

Abstract: The present invention relates to compositions and methods for enhancing the bioavailability of beneficial agents with low water solubility.

Abstract: Various types of holey fiber provide optical propagation. In various embodiments, for example, a large core holey fiber comprises a cladding region formed by large holes arranged in few layers. The number of layers or rows of holes about the large core can be used to coarse tune the leakage losses of the fundamental and higher modes of a signal, thereby allowing the non-fundamental modes to be substantially eliminated by leakage over a given length of fiber. Fine tuning of leakage losses can be performed by adjusting the hole dimension and/or the hole spacing to yield a desired operation with a desired leakage loss of the fundamental mode. Resulting holely fibers have a large hole dimension and spacing, and thus a large core, when compared to traditional fibers and conventional fibers that propagate a single mode. Other loss mechanisms, such as bend loss and modal spacing can be utilized for selected modes of operation of holey fibers. Other embodiments are also provided.

Abstract: This invention relates to novel formulations and methods for the controlled release delivery of topiramate; as well as to the use of these formulations and methods for treating disease.

Abstract: One or more single mode few-moded or multimode fibers are incorporated into a bundle to carry input to a fiber amplifier or output from a fiber amplifier or a fiber laser. The input is at the signal wavelength, which is the wavelength where amplification or lasing occurs. Each of the fibers in the bundle is cleaved individually or as a group and fiber ends are aligned in the same plane. The fiber amplifier or fiber laser may include a double clad fiber and the other fibers of the bundle couple light for cladding pumping. The device may also include a mode filter for controlling the output mode.

Abstract: The present invention relates to compositions and methods for enhancing the dissolution and bioavailibilty of beneficial agents with low water solubility.

Abstract: The present invention includes a dosage form that releases a liquid active agent formulation over a period of time at an ascending rate. The dosage form of the present invention includes a capsule or other reservoir capable of containing a liquid active agent formulation, a driving means for expelling the liquid active agent formulation from the capsule over an extended period of time and a rate altering means for increasing the rate at which the driving means expels liquid active agent formulation from the capsule. The present invention also includes a method of manufacturing a controlled release dosage form providing the release of liquid active agent formulation at an ascending rate.

Abstract: A method of fabricating a band-processing optical fibre filter having a center wavelength &lgr;0′, the method comprises (i) radius-reducing a mismatched multi-core optical fibre having a core phase matching wavelength (before radius reduction) of &lgr;0 and a radius (before radius reduction) of a0, to a reduced radius Ra0, where R=&lgr;0′/&lgr;0; and (ii) providing light input and output connections to a section of the radius-reduced multi-core fibre so that input light is launched into one of the cores of the multi-core fibre section and output light emerges from one of the cores of the multi-core fibre section.