Abstract: The present application relates to a method for in vitro induction and expansion of high-purity and high-cytotoxic NK cells. The method includes: inoculating isolated mononuclear cells in a pre-coated culture flask or a culture dish for culture treatment; and performing activation and induction culture in a culture medium containing monoclonal antibodies and cytokines, to finally obtain NK cells. The coating is performed in a buffer containing anti-CD16 monoclonal antibody and IL-21.

Abstract: A heterodyne laser interferometer and a measurement method based on an integrated dual polarization beam-splitting assembly is provided. Technical points: The first polarization beam splitter and the second polarization beam splitter of the integrated dual polarization beam-splitting assembly are arranged in parallel. The first polarization beam splitter is attached with a first polarizer, a third polarizer, and a first quarter-wave plate; The second polarization beam splitter is attached with a second polarizer, a fourth polarizer, and a second quarter-wave plate; The output optical path of the first quarter-wave plate and the second quarter-wave plate is equipped with target mirrors, while the output optical path of the third quarter-wave plate and the fourth quarter-wave plate is equipped with photodetectors. The assembly and adjustment of the present invention is more flexible and reduce the processing difficulty and processing error.

Abstract: Aromatic heterocyclic compounds as ENPP1 inhibitors, a preparation method therefor and the uses thereof. The compounds have structures as shown in formula (I).

Abstract: Exemplary positioning method and apparatus, a device, a system, a medium and a self-driving vehicle are provided. The positioning method includes determining, according to the current frame of point cloud data collected by a to-be-positioned terminal in a travelling environment, the current key point in the current frame of point cloud data and a point cloud distribution feature of the current key point; selecting, according to point cloud distribution features associated with reference key points in a global positioning map and the point cloud distribution feature of the current key point, a target key point matching the current key point from the reference key points; and determining, according to reference pose data associated with the target key point, the current pose data of the to-be-positioned terminal.

Abstract: Provided is a fusion protein containing GLP-1 and FGF21 linked through an immunoglobulin Fc portion. Each of the GLP-1 and FGF21 can be substituted with its analogues or variants and, the Fc portion, which can be derived from IgG4, can include substitutions that further enhance the fusion protein's stability and activity. These fragments can be linked together through peptide linkers. The fusion protein can be used clinically to reduce glucose and lipid levels and body weight.

Abstract: A heterodyne interferometer and a measurement method based on multi-target opposite displacement measurement are provided, technical points including: An output path of the laser source is sequentially arranged with a first beam splitter and a second beam splitter arranged in parallel on left and right sides, and both of which are polarization beam splitters; a first reflector is arranged above the first beam splitter, a third reflector is arranged on a right side of the second beam splitter, a second plane reflector is arranged in front of the second beam splitter, and a first plane reflector is arranged behind the second beam splitter; the first plane reflector and the second plane reflector jointly constitute a second reflector group; a left side of the first beam splitter is provided with a first photodetector and a second photodetector. The present invention realizes the measurement of relative displacement between opposing objects.

Abstract: A holding mechanism of a slicer, a crystal bar conveying structure and a slicer are provided. The holding mechanism of a slicer includes a holding seat and at least two limiting members. The at least two limiting members are movably disposed on the holding seat. An outer surface of the holding seat is provided with an accommodating groove. When the at least two limiting members are in the avoiding state, at least a part of each of the at least two limiting members is accommodated in the accommodating groove, so as to give way to a crystal bar holder in a moving process of the crystal bar holder. When the at least two limiting members are in the limiting state, at least a part of each of the at least two limiting members protrudes out from the outer surface of the holding seat to abut against the crystal bar holder.

Abstract: Technology for determining a test flow for testing memory during a production phase. The following are accessed: a list of test items with a number of candidate test item conditions for each test item, defects (e.g., bad blocks) detected by each test item condition, a list of benchmark defects (e.g., bad blocks), and judgement criteria. The defects (e.g., bad blocks) for the candidate test item conditions may be compared with the benchmark defects (e.g., bad blocks) in view of judgement criteria. Based on the comparison, at least one test item may be eliminated resulting in a set of remaining test items. A production phase test flow having a test item condition for each remaining test item may be generated.

Abstract: A system for realizing transformation of a thermal power unit based on combined high-parameter and low-parameter molten salts includes a high-parameter molten salt energy storage system, a low-parameter molten salt energy storage system and a thermal power unit. The high-parameter molten salt energy storage system and the low-parameter molten salt energy storage system include an electric heater for heating a molten salt, and an electric energy input end of the electric heater is connected with an electric energy output end of the thermal power unit. The low-parameter molten salt energy storage system includes a low-parameter molten salt heat absorption loop and a low-parameter molten salt heat release loop, and the high-parameter molten salt energy storage system includes a high-parameter molten salt heat absorption loop and a high-parameter molten salt heat release loop.

Abstract: A reading device for capacitive sensing element comprises a differential capacitive sensing element, a modulator, a charge-voltage conversion circuit, a phase adjustment circuit, a demodulator and a low-pass filter. The modulator outputs a modulation signal to the common node of the capacitive sensing element and modulates the output signal of the capacitive sensing element. The two input terminals of the charge-to-voltage conversion circuit are connected to two non-common nodes of the capacitive sensing element. The charge-to-voltage converter read the output charge of the capacitive sensing element and convert it into a voltage signal. The modulator generates a demodulation signal through the phase adjustment circuit. The demodulator receives the demodulation signal from the phase adjustment circuit and demodulates the output of the charge-to-voltage conversion circuit. The low-pass filter is connected to the output of the demodulator for filtering the demodulated voltage signal to output the read signal.

Abstract: A rapid and automatic virus imaging and analysis system includes (i) electron optical sub-systems (EOSs), each of which has a large field of view (FOV) and is capable of instant magnification switching for rapidly scanning a virus sample; (ii) sample management sub-systems (SMSs), each of which automatically loads virus samples into one of the EOSs for virus sample scanning and then unloads the virus samples from the EOS after the virus sample scanning is completed; (iii) virus detection and classification sub-systems (VDCSs), each of which automatically detects and classifies a virus based on images from the EOS virus sample scanning; and (iv) a cloud-based collaboration sub-system for analyzing the virus sample scanning images, storing images from the EOS virus sample scanning, and storing and analyzing machine data associated with the EOSs, the SMSs, and the VDCSs.

Abstract: Provided are a method and molten salt system for recovering rare earth elements from NdFeB waste and use of ferric oxide as a raw material of a manganese-zinc ferrite. The molten salt system comprising the following components in percentage by weight: 40% of K3AlF6 or Na3AlF6, 40% of KBe2F5, and 20% of KAlF4. By adopting the three-component molten salt system of the present invention, recovery rates of rare earth elements extracted from NdFeB waste all can reach 98% or above. By adopting the three-component molten salt system, extraction temperature is 100-400° C. lower than that of all current similar halogenation methods, and extraction time is fold shorted to 1-3 h. The reduction of the extraction temperature and the shortening of the melting time greatly reduce the energy consumption of extracting rare earth elements from NdFeB waste, and the economic benefits are remarkable.

Abstract: Provided is a method for preparing a soft magnetic manganese-zinc ferrite composite by removing impurities from industrial waste step by step. Manganese-containing waste residue is crushed and dried, and then mixed with a flux in a muffle furnace and roasted at a temperature below 1000° C. till solid-liquid stratification; then, multi-step impurity removal is performed to obtain a high-purity quaternary purification solution of manganese sulfate. Similarly, zinc residue is melted to remove impurities, and then multi-step impurity removal is performed to obtain a high-purity quaternary purification solution of zinc sulfate. According to a manganese-zinc-iron ratio required for the manganese-zinc ferrite, the two purification solutions are mixed, and ferrous sulfate is added.

Abstract: Provided are a method and molten salt system for recovering rare earth elements from NdFeB waste and use of ferric oxide as a raw material of a manganese-zinc ferrite. The molten salt system comprising the following components in percentage by weight: 40% of K3AlF6 or Na3AlF6, 40% of KBe2F5, and 20% of KAlF4. By adopting the three-component molten salt system of the present invention, recovery rates of rare earth elements extracted from NdFeB waste all can reach 98% or above. By adopting the three-component molten salt system, extraction temperature is 100-400° C. lower than that of all current similar halogenation methods, and extraction time is fold shorted to 1-3 h. The reduction of the extraction temperature and the shortening of the melting time greatly reduce the energy consumption of extracting rare earth elements from NdFeB waste, and the economic benefits are remarkable.

Abstract: The present invention provides a backscattered electron (BSE) detector comprising two or more detection components that are electrically isolated from each other. Each of the detection components includes a single continuous top metal layer configured for directly receiving incident backscattered electrons and for backscattered electron to penetrate therethrough. The thickness of one of the top metal layers is different from the thickness of another one of the top metal layers. The BSE detector can be used in an apparatus of charged-particle beam for imaging a sample material. Signals from the detection components having top metal layers of different thicknesses can be inputted into different signal amplifier circuits to get different energy bands of BSE image.

Abstract: The present invention provides a MEMS sample holder comprising an observation section. The observation section includes a first layer, a second layer, and a sample compartment between the first layer and the second layer. The sample compartment is configured for filling a liquid sample and observing the liquid sample filled therewithin. The sample compartment has one, two or more windows through which an electron beam can pass. Each of the windows is formed on two cavities including a first cavity on the first layer and a second cavity on the second layer that is opposite to the first cavity across the sample compartment.

Abstract: Rectification is a process that converts electromagnetic fields into direct current (DC). Such a process underlies a wide range of technologies, including wireless communication, wireless charging, energy harvesting, and infrared detection. Existing rectifiers are mostly based on semiconductor diodes, with limited applicability to small voltages or high frequency inputs. Here, we present an alternative approach to current rectification that uses the electronic properties of quantum crystals without semiconductor junctions. We identify a new mechanism for rectification from skew scattering due to the chirality of itinerant electrons in time-reversal-invariant but inversion-breaking materials. Our calculations reveal large, tunable rectification effects in graphene multilayers and transition metal dichalcogenides. These effects can be used in high-frequency rectifiers by rational material design and quantum wavefunction engineering.

Abstract: A method for synchronous production of manganese tetraoxide and ferric oxide for a soft magnetic material by using marine polymetallic nodules includes: 1) crushing and grinding marine manganese nodules and baking to a constant weight; thoroughly mixing with a mixed flux and roasting in a muffle furnace; 2) carrying out solid-liquid separation, washing solid-phase precipitates with water, grinding the solid, adding sulfuric acid, controlling the temperature to be below 50° C., and vacuuming a reactor up; 3) adding a reducing agent to react at room temperature for 5-10 min, adding ammonia water to adjust the pH value to 5.5, and carrying out separation and filtering; 4) controlling the temperatures of manganese sulfate and ferric sulfate solutions to be below 50° C., and adding ammonium sulfide; and 5) washing with deionized water, and calcining at 800-900° C. for 1-3 s by a suspension low-temperature instantaneous firing system.

Abstract: A rapid and automatic virus imaging and analysis system includes (i) electron optical sub-systems (EOSs), each of which has a large field of view (FOV) and is capable of instant magnification switching for rapidly scanning a virus sample; (ii) sample management sub-systems (SMSs), each of which automatically loads virus samples into one of the EOSs for virus sample scanning and then unloads the virus samples from the EOS after the virus sample scanning is completed; (iii) virus detection and classification sub-systems (VDCSs), each of which automatically detects and classifies a virus based on images from the EOS virus sample scanning; and (iv) a cloud-based collaboration sub-system for analyzing the virus sample scanning images, storing images from the EOS virus sample scanning, and storing and analyzing machine data associated with the EOSs, the SMSs, and the VDCSs.

Abstract: The present invention provides an apparatus of electron beam comprising an electron gun with a pinnacle limiting plate having at least one current-limiting aperture. The pinnacle limiting plate is located between a bottom (or lowest) anode and a top (or highest) condenser within the electron gun. A current (ampere) of the electron beam that has passed through the current-limiting aperture remains the same (unchanged) after the electron beam travels through the top condenser and an electron optical column and arrives at a sample space. Electron-electron interaction of the electron beam is thus reduced.