Patents by Inventor Liang-Jung Chien

Liang-Jung Chien has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20250215468
    Abstract: A method for converting a carbon source into serine includes: synthesizing a DNA sequence; implanting the DNA sequence into a plasmid, so that the plasmid includes gene sequences of SEQ ID NO: 1, SEQ ID NO: 2, and SEQ ID NO: 3; implanting the plasmid into cyanobacteria through an electroporation treatment, so as to obtain modified cyanobacteria; and providing the carbon source to the modified cyanobacteria, so that the modified cyanobacteria convert the carbon source into the serine.
    Type: Application
    Filed: April 11, 2024
    Publication date: July 3, 2025
    Inventors: TE-CHAO LIAO, JUNG-JEN CHUANG, YI-CHENG LI, Tzu-Huan Wong, Liang-Jung Chien
  • Publication number: 20250215466
    Abstract: A method for producing phosphatidylethanolamine with use of a carbon source includes: cultivating modified cyanobacteria, in which the modified cyanobacteria are cultivated in a liquid medium; undergoing a photo-fermentation process, in which the carbon source is provided to the modified cyanobacteria, so that the modified cyanobacteria convert the carbon source into serine; undergoing a filtration process, in which the liquid medium is filtered for separating the modified cyanobacteria, so as to obtain the filtered liquid medium; synthesizing the phosphatidylethanolamine, in which the filtered liquid medium and the serine are mixed with a lecithin and a phospholipase in a photoreactor, so as to obtain a phosphatidylethanolamine mixture; and undergoing an oil-water separation process, in which the phosphatidylethanolamine mixture is placed in an oil water separator and left to rest for a predetermined period of time, and the phosphatidylethanolamine is obtained from an upper layer of the phosphatidylethanolam
    Type: Application
    Filed: April 11, 2024
    Publication date: July 3, 2025
    Inventors: TE-CHAO LIAO, JUNG-JEN CHUANG, YI-CHENG LI, Tzu-Huan Wong, Liang-Jung Chien
  • Publication number: 20250188443
    Abstract: A method for cultivating cyanobacteria includes: providing the cyanobacteria; subjecting the cyanobacteria to physical mutagenesis, so as to obtain primary mutant cyanobacteria; subjecting the primary mutant cyanobacteria to chemical mutagenesis, so as to obtain secondary mutant cyanobacteria; and subjecting the secondary mutant cyanobacteria to a temperature resistance test and an environment resistance test, so as to obtain target cyanobacteria. A fatality rate of the physical mutagenesis ranges between 50% and 80%, and a fatality rate of the chemical mutagenesis ranges between 40% and 55%.
    Type: Application
    Filed: January 30, 2024
    Publication date: June 12, 2025
    Inventors: TE-CHAO LIAO, JUNG-JEN CHUANG, YI-CHENG LI, Tzu-Huan Wong, Liang-Jung Chien
  • Patent number: 9695404
    Abstract: Described herein are genetically-modified microorganisms for producing long-chain dicarboxylic acids and methods of using the microorganisms. The microorganisms contain a first nucleic acid encoding an Umbellularia californica lauroyl ACP-thioesterase (BTE) operably linked to a promoter or a second nucleic acid encoding a Cocos nucifera lauroyl ACP-thioesterase (FatB3) operably linked to a promoter.
    Type: Grant
    Filed: July 17, 2015
    Date of Patent: July 4, 2017
    Assignee: Industrial Technology Research Institute
    Inventors: Hsin-Ju Hsieh, Liang-Jung Chien, Jia-Hung Wang, Yu-Ju Lin
  • Publication number: 20160017387
    Abstract: Described herein are genetically-modified microorganisms for producing long-chain dicarboxylic acids and methods of using the microorganisms. The microorganisms contain a first nucleic acid encoding an Umbellularia californica lauroyl ACP-thioesterase (BTE) operably linked to a promoter or a second nucleic acid encoding a Cocos nucifera lauroyl ACP-thioesterase (FatB3) operably linked to a promoter.
    Type: Application
    Filed: July 17, 2015
    Publication date: January 21, 2016
    Inventors: Hsin-Ju Hsieh, Liang-Jung Chien, Jia-Hung Wang, Yu-Ju Lin