Abstract: A technique for providing search results may include determining a first entity type, a second entity type, and a relationship type based on a compositional query. The technique may also include identifying nodes of a knowledge graph corresponding to entity references of the first entity type and entity references of the second entity type. The technique may also include determining from the knowledge graph an attribute value corresponding to the relationship type for each entity reference of the first entity type and for each entity reference of the second entity type. The technique may also include comparing the attribute value of each entity reference of the first entity type with the attribute value of each entity reference of the second entity type. The technique may also include determining one or more resultant entity references from the entity references of the first entity type based on the comparing.

Abstract: The present invention relates to a multifunctional cyclic-dinucleotide compound of formula (X) and its derivatives, which can be used as a prodrug of an apoptosis inducer or a cytotoxic agent for inducing cell apoptosis or anti-virus, and can also regulate immunity pathway to generate a therapeutically beneficial immune response. The present disclosure further relates to pharmaceutical compositions and pharmaceutical combinations comprising the cyclic-dinucleotide compounds of the present invention, methods for synthesizing them, and medical uses thereof.

Abstract: Embodiments provide an ultrasound transducer. The ultrasound transducer may include a multi-layered membrane having a plurality of slits extending through the membrane, thereby forming a plurality of sections of the membrane at least partially separated by the slits. Each slit extends from a perimeter of the membrane to a respective end position at a predetermined distance away from a center of the membrane. The plurality of sections of the membrane are connected to each other at the center of the membrane.

Abstract: A photothermal deflection measuring system includes a substrate, a detecting light source, a detecting unit, and a processor. The substrate includes a plurality of positioning structures, on each of which supports a cell emitting heat outside a surface thereof. The detecting light source is utilized to project a detecting light passing through a specific position outside the surface whereby the detecting light is deflected due to a thermal gradient caused by the emitted heat. The detecting unit is arranged at a side of the cell for receiving the deflected detecting light thereby generating an optical deflection signal corresponding to a deflection of the deflected detecting light. The processor is configured to receive the optical deflection signal, analyze the optical deflection signal and determine a heat value corresponding to the specific position out side the surface of the cell according to the optical deflection signal.

Abstract: A photothermal deflection measuring system includes a substrate, a detecting light source, a detecting unit, and a processor. The substrate includes a plurality of positioning structures, on each of which supports a cell emitting heat outside a surface thereof. The detecting light source is utilized to project a detecting light passing through a specific position outside the surface whereby the detecting light is deflected due to a thermal gradient caused by the emitted heat. The detecting unit is arranged at a side of the cell for receiving the deflected detecting light thereby generating an optical deflection signal corresponding to a deflection of the deflected detecting light. The processor is configured to receive the optical deflection signal, analyze the optical deflection signal and determine a heat value corresponding to the specific position out side the surface of the cell according to the optical deflection signal.

Abstract: Embodiments provide an ultrasound transducer. The ultrasound transducer may include a multi-layered membrane having a plurality of slits extending through the membrane, thereby forming a plurality of sections of the membrane at least partially separated by the slits. Each slit extends from a perimeter of the membrane to a respective end position at a predetermined distance away from a center of the membrane. The plurality of sections of the membrane are connected to each other at the center of the membrane.

Abstract: A transducer is provided, which includes a substrate, wherein a cavity is defined at least partially through the substrate, at least one stopper structure arranged within the cavity, a support layer arranged over the at least one stopper structure and the cavity to seal the cavity, and a piezoelectric functional arrangement arranged on the support layer. According to further embodiments of the present invention, a method for forming a transducer is also provided.

Abstract: According to various embodiments, there is provided a thrombolysis device including a catheter configured to be inserted into a blood clot; a treatment transducer coupled to the catheter, the treatment transducer configured to transmit acoustic waves; a measurement transducer coupled to the catheter, the measurement transducer configured to transmit further acoustic waves and further configured to receive acoustic echoes, the acoustic echoes being reflections of the further acoustic waves from a boundary of the blood clot, wherein the measurement transducer is further configured to provide a measurement output; a determination circuit configured to determine at least one of a viscosity of blood in a vicinity of the measurement transducer or a volume of the blood clot, based on the measurement output; and a control circuit configured to generate control signals for controlling the treatment transducer, based on at least one from the group consisting of the viscosity of blood in the vicinity of the measurement

Abstract: A method for inducing thrombosis in an artery of a living animal includes: implanting an implantable medical device into a living animal, the implantable medical device including a light-emitting element and a wireless power receiver; administrating a photo-sensitizing dye material into the living animal; and providing wirelessly a control signal, from an external power controller, to the wireless power receiver which transmits electrical power to the light-emitting element in response to the control signal to drive the light-emitting element to emit light for irradiating the artery of the living animal.

Abstract: A transducer is provided, which includes a substrate, wherein a cavity is defined at least partially through the substrate, at least one stopper structure arranged within the cavity, a support layer arranged over the at least one stopper structure and the cavity to seal the cavity, and a piezoelectric functional arrangement arranged on the support layer. According to further embodiments of the present invention, a method for forming a transducer is also provided.

Abstract: An induction device for photodynamic therapy and diagnosis is used in a living body, and for activating a photochemical reaction of a photosensitive agent in the living body. The induction device comprises a transmitter, and a light irradiator implanted in the living body. The transmitter is used for emitting a radio signal to penetrate a superficial layer of the living body. When the light irradiator receives the radio signal, the light irradiator emits light by the driving signal, such that the photosensitive agent undergoes a photochemical reaction.