Abstract: The present disclosure relates to devices and methods for sensing ACVG. In one example, the device comprises an ACVG sensor for sensing signals of heart beat and arterial pulse in a predetermined period. The ACVG sensor transforms the signals to electrical output. The analog-to-digital converter receives the electrical output and converts the electrical output into digital signals. The present disclosure further relates to methods of determining physiological conditions. In one example, the method comprises receiving an ACVG, providing a waveform data by processing the ACVG, extracting at least one data point from a predetermined time interval of the waveform data, obtaining indicators based on the at least one data point, and determining a physiological condition according to the indicator.