Patents by Inventor Liang Shan

Liang Shan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10463028
    Abstract: Genetically modified non-human animals expressing human EPO from the animal genome are provided. Also provided are methods for making non-human animals expressing human EPO from the non-human animal genome, and methods for using non-human animals expressing human EPO from the non-human animal genome. These animals and methods find many uses in the art, including, for example, in modeling human erythropoiesis and erythrocyte function; in modeling human pathogen infection of erythrocytes; in in vivo screens for agents that modulate erythropoiesis and/or erythrocyte function, e.g. in a healthy or a diseased state; in in vivo screens for agents that are toxic to erythrocytes or erythrocyte progenitors; in in vivo screens for agents that prevent against, mitigate, or reverse the toxic effects of toxic agents on erythrocytes or erythrocyte progenitors; in in vivo screens of erythrocytes or erythrocyte progenitors from an individual to predict the responsiveness of an individual to a disease therapy.
    Type: Grant
    Filed: May 18, 2015
    Date of Patent: November 5, 2019
    Assignees: Regeneron Pharmaceuticals, Inc., Yale University, Institute for Research in Biomedicine (IRB)
    Inventors: Andrew J. Murphy, Sean Stevens, Richard Flavell, Markus Gabriel Manz, Liang Shan
  • Patent number: 10225949
    Abstract: A method for controlling the rotational speed of a fan of an LED lamp, comprising: presetting a corresponding relationship between a voltage, a current and a temperature for an LED chip in the LED lamp in the controller, as well as presetting a corresponding relationship between the temperature of LED chip and the speed of the fan in the controller, measuring the voltage and current of the LED chip, obtaining the current calculated temperature of the LED chip through the measured voltage and current, and further determining the current desired fan speed through the obtained current calculated temperature, using the controller to control the fan to rotate at the current desired speed, thereby cooling the LED chip. Additionally a corresponding system for controlling the rotational speed of the fan of an LED lamp and an LED lamp including the system.
    Type: Grant
    Filed: December 6, 2017
    Date of Patent: March 5, 2019
    Assignee: GE Lighting Solutions, LLC
    Inventors: Min Fang, Qi Long, Liang Shan, Shuyi Qin, Yong Li
  • Patent number: 10123518
    Abstract: Genetically modified non-human animals expressing human SIRP? and human IL-15 from the non-human animal genome are provided. Also provided are methods for making non-human animals expressing human SIRP? and human IL-15 from the non-human animal genome, and methods for using non-human animals expressing human SIRP? and human IL-15 from the non-human animal genome. These animals and methods find many uses in the art, including, for example, in modeling human T cell and/or natural killer (NK) cell development and function, in modeling human pathogen infection of human T cells and/or NK cells, and in various in vivo screens.
    Type: Grant
    Filed: April 12, 2016
    Date of Patent: November 13, 2018
    Assignees: Regeneron Pharmaceuticals, Inc, Yale University, Institute For Research In Biomedicine (IRB)
    Inventors: Dietmar Herndler-Brandstetter, Richard A. Flavell, Davor Frleta, Cagan Gurer, Markus Gabriel Manz, Andrew J. Murphy, Noah W. Palm, Liang Shan, Sean Stevens, Till Strowig, George D. Yancopoulos, Marcel de Zoete
  • Publication number: 20180295820
    Abstract: Genetically modified non-human animals expressing human SIRP? and human IL-15 from the non-human animal genome are provided. Also provided are methods for making non-human animals expressing human SIRP? and human IL-15 from the non-human animal genome, and methods for using non-human animals expressing human SIRP? and human IL-15 from the non-human animal genome. These animals and methods find many uses in the art, including, for example, in modeling human T cell and/or natural killer (NK) cell development and function, in modeling human pathogen infection of human T cells and/or NK cells, and in various in vivo screens.
    Type: Application
    Filed: April 16, 2018
    Publication date: October 18, 2018
    Inventors: Dietmar Herndler-Brandstetter, Richard A. Flavell, Davor Frleta, Cagan Gurer, Markus Gabriel Manz, Andrew J. Murphy, Noah W. Palm, Liang Shan, Sean Stevens, Till Strowig, George D. Yancopoulos, Marcel de Zoete
  • Publication number: 20180160564
    Abstract: A method for controlling the rotational speed of a fan of an LED lamp, comprising: presetting a corresponding relationship between a voltage, a current and a temperature for an LED chip in the LED lamp in the controller, as well as presetting a corresponding relationship between the temperature of LED chip and the speed of the fan in the controller, measuring the voltage and current of the LED chip, obtaining the current calculated temperature of the LED chip through the measured voltage and current, and further determining the current desired fan speed through the obtained current calculated temperature, using the controller to control the fan to rotate at the current desired speed, thereby cooling the LED chip. Additionally a corresponding system for controlling the rotational speed of the fan of an LED lamp and an LED lamp including the system.
    Type: Application
    Filed: December 6, 2017
    Publication date: June 7, 2018
    Inventors: Min FANG, Qi LONG, Liang SHAN, Shuyi QIN, Yong LI
  • Publication number: 20170360920
    Abstract: Described herein are methods of preventing or treating a HIV infection comprising administering to a mammal in need thereof, a pharmaceutically effective amount of a CD8+ T cell vaccine composition. Such methods comprising using CD8+ T cells which have been pre-stimulated with at least one HIV epitope, to thereby enhance a CD8+ T cell immune response against HIV in said mammal.
    Type: Application
    Filed: November 20, 2015
    Publication date: December 21, 2017
    Inventors: Robert Siliciano, Kai Deng, Liang Shan
  • Publication number: 20170274001
    Abstract: The invention relates generally to a composition and method for increasing the frequency, amount, or presence of red blood cells in peripheral blood. In one embodiment, the invention comprises the inhibition of, or genetic modification of the genes encoding, one or more scavenger receptors. In one aspect, the invention relates to treatments of anemia.
    Type: Application
    Filed: September 8, 2015
    Publication date: September 28, 2017
    Inventors: Richard Flavell, Liang Shan
  • Publication number: 20160295844
    Abstract: Genetically modified non-human animals expressing human SIRP? and human IL-15 from the non-human animal genome are provided. Also provided are methods for making non-human animals expressing human SIRP? and human IL-15 from the non-human animal genome, and methods for using non-human animals expressing human SIRP? and human IL-15 from the non-human animal genome. These animals and methods find many uses in the art, including, for example, in modeling human T cell and/or natural killer (NK) cell development and function, in modeling human pathogen infection of human T cells and/or NK cells, and in various in vivo screens.
    Type: Application
    Filed: April 12, 2016
    Publication date: October 13, 2016
    Inventors: Dietmar Herndler-Brandstetter, Richard A. Flavell, Davor Frleta, Cagan Gurer, Markus Gabriel Manz, Andrew J. Murphy, Noah W. Palm, Liang Shan, Sean Stevens, Till Strowig, George D. Yancopoulos, Marcel de Zoete
  • Publication number: 20150327524
    Abstract: Genetically modified non-human animals expressing human EPO from the animal genome are provided. Also provided are methods for making non-human animals expressing human EPO from the non-human animal genome, and methods for using non-human animals expressing human EPO from the non-human animal genome. These animals and methods find many uses in the art, including, for example, in modeling human erythropoiesis and erythrocyte function; in modeling human pathogen infection of erythrocytes; in in vivo screens for agents that modulate erythropoiesis and/or erythrocyte function, e.g. in a healthy or a diseased state; in in vivo screens for agents that are toxic to erythrocytes or erythrocyte progenitors; in in vivo screens for agents that prevent against, mitigate, or reverse the toxic effects of toxic agents on erythrocytes or erythrocyte progenitors; in in vivo screens of erythrocytes or erythrocyte progenitors from an individual to predict the responsiveness of an individual to a disease therapy.
    Type: Application
    Filed: May 18, 2015
    Publication date: November 19, 2015
    Inventors: Andrew J. Murphy, Sean Stevens, Richard Flavell, Markus Gabriel Manz, Liang Shan
  • Patent number: 8971929
    Abstract: The disclosure discloses a method and a system for transmitting location data. The method comprises at least one step of that: the location data is transmitted between a first terminal and a second terminal; the location data is transmitted between a first location server and a second location server; and the location data is transmitted between a third terminal and a third location server, wherein the location data comprises: assistance location data and/or position data. According to the technical solution provided by the disclosure, the location function between two terminals supporting Security User Plane Location (SUPL) can be realized, and some novel assistance location data can be transmitted.
    Type: Grant
    Filed: March 25, 2011
    Date of Patent: March 3, 2015
    Assignee: ZTE Corporation
    Inventors: Hui Li, Liang Shan
  • Patent number: 8965396
    Abstract: This document discusses a location system, method, server and terminal. A location information server provides a Secure User Plane for Location, SUPL, Enabled Terminal, SET, with location information regarding the SET in a form of reference; the SET provides a Secure User Plane for Location, SUPL, server with the location information reference regarding the SET via an SUPL message; the SUPL server obtains the location information regarding the SET from the location information server according to the location information reference transmitted by the SET.
    Type: Grant
    Filed: March 24, 2010
    Date of Patent: February 24, 2015
    Assignee: ZTE Corporation
    Inventors: Hui Li, Liang Shan
  • Patent number: 8744409
    Abstract: A method for locating a Secure User Plane Location (SUPL) Enabled Terminal (SET) is provided by the present invention. The method includes that: the SET obtaining the location service information of the local access network when accessing the local access network, wherein the location service information includes the address and/or identification of at least one of the location server in the local access network; the SET transmitting the location service information of the local access network to the Home SUPL Location Platform (H-SLP) of the SET; and the SET receiving the location service information transmitted by the H-SLP, wherein the location service information includes the address and/or identification of the location server providing the location service for the SET in the local access network. An SET and an H-SLP are also provided by the present invention.
    Type: Grant
    Filed: March 25, 2011
    Date of Patent: June 3, 2014
    Assignee: ZTE Corporation
    Inventors: Hui Li, Liang Shan
  • Publication number: 20130017844
    Abstract: The disclosure discloses a method and a system for transmitting location data. The method comprises at least one step of that: the location data is transmitted between a first terminal and a second terminal; the location data is transmitted between a first location server and a second location server; and the location data is transmitted between a third terminal and a third location server, wherein the location data comprises: assistance location data and/or position data. According to the technical solution provided by the disclosure, the location function between two terminals supporting Security User Plane Location (SUPL) can be realized, and some novel assistance location data can be transmitted.
    Type: Application
    Filed: March 25, 2011
    Publication date: January 17, 2013
    Applicant: ZTE Corporation
    Inventors: Hui Li, Liang Shan
  • Publication number: 20130012166
    Abstract: A method for locating a Secure User Plane Location (SUPL) Enabled Terminal (SET) is provided by the present invention. The method includes that: the SET obtaining the location service information of the local access network when accessing the local access network, wherein the location service information includes the address and/or identification of at least one of the location server in the local access network; the SET transmitting the location service information of the local access network to the Home SUPL Location Platform (H-SLP) of the SET; and the SET receiving the location service information transmitted by the H-SLP, wherein the location service information includes the address and/or identification of the location server providing the location service for the SET in the local access network. An SET and an H-SLP are also provided by the present invention.
    Type: Application
    Filed: March 25, 2011
    Publication date: January 10, 2013
    Applicant: ZTE CORPORATION
    Inventors: Hui Li, Liang Shan
  • Publication number: 20120184293
    Abstract: The present disclosure discloses a location system, method, server and terminal. In the scheme of the present disclosure, a location information server provides a Secure User Plane for Location (SUPL) Enabled Terminal (SET) with location information regarding the SET in a form of reference; the SET provides a Secure User Plane for Location (SUPL) server with location information corresponding to the location information reference regarding the SET; the SUPL server obtains the location information regarding the SET for the location information server according to the location information reference transmitted by the SET, to enable the convergence of the mainstream location architecture based on the SUPL of Open Mobile Architecture (OMA) Location (LOC) group and another mainstream location architecture based on the Location Configuration Protocol (LCP) of the Internet Engineering Task Force (IETF).
    Type: Application
    Filed: March 24, 2010
    Publication date: July 19, 2012
    Applicant: ZTE CORPORATION
    Inventors: Hui Li, Liang Shan
  • Publication number: 20120126718
    Abstract: An inspection fixture for inspecting an LED array of a circuit board under test through a power supply unit, includes: an inspection base having a testing platform with a plurality of pairs of anode and cathode probes corresponding to anode and cathode pins of the LEDs of the LED array, each pair being electrically connected to the power supply unit to constitute a power supply circuit; a carrier board used for carrying the circuit board under test and having through holes corresponding to the anode and cathode probes; and a pressing member for pressing the circuit board and driving the carrier board to move so as to enable the anode and cathode probes to pass through the through holes and come into contact with the anode and cathode pins of the LEDs, thereby supplying power to each of the LEDs to emit light through the power supply circuit.
    Type: Application
    Filed: December 7, 2010
    Publication date: May 24, 2012
    Applicant: Askey Computer Corporation
    Inventors: Shi-Liang Shan, Xiao-Bo Zhu, Ching-Feng Hsieh