Abstract: The technical field of active substance preparations is belonged to, and provided are astaxanthin pickering emulsion with colon targeted delivery function, and a preparation method and application method thereof. The preparation method includes the following steps: S1, reparation of deacetylated-oxidized chitin nanofiber (DE-TO-ChNF)/carboxymethyl konjac glucomannan (CMKGM) nanogel; S2, preparation of astaxanthin oil phase; and S3, preparation astaxanthin pickering emulsion. Natural polysaccharide derivatives DE-TO-ChNF and CMKGM are used as raw materials, and stable crosslinking between covalent bonds and non-covalent bonds are formed between molecules in a composite system through the NHS/EDC, so as to form a stable nanogel. Then the nanogel is used as emulsifier and flaxseed oil rich in astaxanthin is used as oil phase to prepare the astaxanthin pickering emulsion by homogenization.

Abstract: Various embodiments of the present disclosure are directed towards an integrated chip. The integrated chip includes an interconnect structure overlying a semiconductor substrate and comprising a conductive wire. A passivation structure overlies the interconnect structure. An upper conductive structure overlies the passivation structure and comprises a first conductive layer, a dielectric layer, and a second conductive layer. The first conductive layer is disposed between the dielectric layer and the passivation structure. The second conductive layer extends along a top surface of the dielectric layer and penetrates through the first conductive layer and the passivation structure to the conductive wire.

Abstract: Provided herein are bioactive molecule conjugates, preparation methods and use thereof, particularly bioactive molecule conjugates (such as antibody-drug conjugates and small molecule drug conjugates) obtained by improved coupling of a drug and a targeting moiety, as well as their preparation method and use for the treatment of a disease associated with an abnormal cell activity.

Abstract: Disclosed are a cathode active material for sodium-ion batteries and a preparation method therefor and an application thereof. The cathode active material has a chemical formula of NaxNiyFezMngMhAmO2, where M is selected from the group consisting of Ti, Al, Mg, Ca, Zr, Y, Zn, Nb, W and combinations thereof, A is selected from the group consisting of B, P, C and combinations thereof, 0.80?x?1.40, 0.05?y?0.95, 0.05?z?0.95, 0.05?g?0.95, 0.01?h?0.50, and 0.01?m?0.30. By adding M and A elements to the ternary iron-manganese-nickel cathode active material for sodium-ion batteries, and controlling the ratio of all elements, the present disclosure can achieve the formation of a perfect layered single-crystal structure of the cathode active material for sodium-ion batteries, with large particles, ultimately achieving the stability of the active material, and when used in sodium-ion batteries, it can significantly improve the cycling performance at high temperatures while ensuring high gram capacity.

Abstract: An autonomous cleaning device and a noise reduction air duct device are provided for autonomous cleaning device. The autonomous cleaning device includes a body and a motor arranged on the body, and the noise reduction air duct device is mounted on the body. The noise reduction air duct device includes an upper housing, a lower housing and a support noise reduction structure made of elastic material. The lower housing and the upper housing enclose to form an air duct, an air inlet is arranged at a position of the air duct corresponding to the motor, and an air outlet is arranged on a side of the air duct away from the air inlet; the support noise reduction structure has a first end fixed on the lower housing, and a second end abutting against a lower surface of the upper housing.

Abstract: A liquid-cooling fracturing system includes a fracturing device; a power device connected to the fracturing device through a transmission device and configured to provide power for the fracturing device; a cooling medium storage device configured to store a cooling medium for cooling the power device; and a first heat exchange device, the first heat exchange device using cooling liquid to exchange heat with the cooling medium to cool the cooling medium.

Abstract: A snow thrower includes a motor, an auger driven by the motor to rotate, a handle device for a user to operate, an auger housing for containing the auger and a frame for connecting the handle device and the auger housing. The auger housing is made of at least two different materials.

Abstract: A method of biasing a substrate includes electrically connecting a silicide structure to a bias voltage supply. The method further includes conducting a bias voltage received by the silicide structure to a silicide extension extending from a main body of the silicide structure, wherein the silicide extension extends between adjacent gate structures of a plurality of first gate structures. The method further includes transferring the bias voltage from the silicide extension into a doped region of a substrate below the adjacent gate structures of the plurality of first gate structures.

Abstract: A casing assembly for accommodating a stylus includes a casing and a button. The casing has an accommodation recess and an opening in communication with each other. The accommodation recess has a first end and a second end opposite to each other on a longitudinal axis thereof, and accommodates the stylus. The opening extends from the first end to the second end. The button includes an operation portion and a pushing portion connected to each other. The operation portion is pivotally disposed at the casing so as to be pivotable between an initial position and a released position. The pushing portion is located in the accommodation recess. When the operation portion is pivoted from the initial position to the released position, the pushing portion in the accommodation recess is moved toward the opening so as to push the stylus out of the accommodation recess.

Abstract: An automatic cleaning apparatus includes: a chassis; a front housing arranged at a front end of the chassis; and a sensing device capable sensing movement of the front housing and sending a signal to a control mainboard of the automatic cleaning apparatus when the front housing touches an obstacle and moves relative to the chassis. The sensing device includes a dust blocking member and a rocker arm that triggers the sensing device to send the signal. The rocker arm has a first end rotatably arranged inside the sensing device, and a second end passing through the dust blocking member and extending out of the sensing device. A front housing reset device is arranged on the chassis and capable of biasing the front housing toward an initial position of the front housing.

Abstract: A semiconductor device includes a first doped region in a substrate, wherein the first doped region has a first dopant type. The semiconductor device further includes a second doped region in the substrate, wherein the second doped region has a second dopant type opposite the first dopant type. The semiconductor device further includes a silicide structure on the substrate, wherein the silicide structure includes a main body and a silicide extension. The semiconductor device further includes a plurality of first gate structures on the substrate, wherein a space between adjacent gate structures of the plurality of first gate structures includes a first area and a second area, the silicide extension extends into the first area, the first doped region is in the substrate below the first area, and the second doped region is in the substrate below the second area.

Abstract: Methods and systems for simulating a stent in a coronary artery lumen structure are disclosed. A method of simulating a stent in a coronary artery lumen structure, the method comprises: reconstructing a three-dimensional coronary artery tree from segmented coronary lumen contours; replacing part of the three-dimensional artery tree with a candidate stent structure; and simulating pressure distribution through the coronary artery tree to determine a non-invasive fractional flow reserve through the candidate stent structure.

Abstract: An integrated circuit includes an array of first-type active-region structures and an array of second-type active-region structures extending in a first direction between a first vertical zone-boundary of a first keep-out zone and the second vertical zone-boundary of a second keep-out zone. The integrated circuit also includes an array of first-side boundary cells aligned with the first vertical zone-boundary and an array of second-side boundary cells aligned with the second vertical zone-boundary. In the array of first-side boundary cells, a first-side boundary cell has a first ESD protection circuit and a pick-up region. In the array of second-side boundary cells, a second-side boundary cell has a second ESD protection circuit.

Abstract: The present application provides a floating device and a robotic pool cleaner, which relate to the technical field of swimming pool cleaning. the floating device has a wireless communication function, so that instructions can be transmitted to the wireless transmission module remotely through a remote controller, thereby controlling the walking and working status of the cleaning device of the robotic pool cleaner, which can realize intelligent cleaning path planning, and can also know the working position and working status of the robotic pool cleaner in time, which greatly improves the convenience of use and cleaning efficiency.

Abstract: A casing assembly for accommodating a stylus includes a casing and a button. The casing has an accommodation recess and an opening in communication with each other. The accommodation recess has a first end and a second end opposite to each other on a longitudinal axis thereof, and accommodates the stylus. The opening extends from the first end to the second end. The button includes an operation portion and a pushing portion connected to each other. The operation portion is pivotally disposed at the casing so as to be pivotable between an initial position and a released position. The pushing portion is located in the accommodation recess. When the operation portion is pivoted from the initial position to the released position, the pushing portion in the accommodation recess is moved toward the opening so as to push the stylus out of the accommodation recess.