Abstract: A high-definition map system receives sensor data from vehicles travelling along routes and combines the data to generate a high definition map for use in driving vehicles, for example, for guiding autonomous vehicles. A pose graph is built from the collected data, each pose representing location and orientation of a vehicle. The pose graph is optimized to minimize constraints between poses. Points associated with surface are assigned a confidence measure determined using a measure of hardness/softness of the surface. A machine-learning-based result filter detects bad alignment results and prevents them from being entered in the subsequent global pose optimization. The alignment framework is parallelizable for execution using a parallel/distributed architecture. Alignment hot spots are detected for further verification and improvement.

Abstract: Disclosed are a non-oriented electrical steel plate with low iron loss and high magnetic conductivity and a manufacturing process therefor. The casting blank of the steel plate comprises the following components: Si: 0.1-2.0 wt %, Al: 0.1-1.0 wt %, Mn: 0.10-1.0 wt %, C: ?0.005 wt %, P: ?0.2 wt %, S: ?0.005 wt %, N: ?0.005 wt %, the balance being Fe and unavoidable impurities. The magnetic conductivity of the steel plate meets the following relationship formula: ?10+?13+?15?13982?586.5P15/50; ?10+?13+?15?10000, wherein P15/50 is the iron loss at a magnetic induction intensity of 1.5 T at 50 Hz; ?10, ?13, and ?15 is are relative magnetic conductivities at induction intensities of 1.0 T, 1.3 T, and 1.5 T at 50 Hz, respectively. The steel plate can be used for manufacturing highly effective and ultra-highly effective electric motors.

Abstract: A method for producing a silicon steel normalizing substrate comprises: steelmaking, hot rolling and normalizing steps. The normalizing step uses a normalizing furnace having a nonoxidizing heating furnace section. The nonoxidizing heating furnace section comprises more than 3 furnace zones. An energy investment ratio of the furnace zones used in the nonoxidizing heating furnace section is adjusted, so as to control an excess coefficient ? of the nonoxidizing heating furnace section to be within a range of 0.8??<1.0.

Abstract: A manufacture method of high-efficiency non-oriented silicon steel with excellent magnetic property includes the steps of smelting a chemical composition of non-oriented silicon steel, by weight percent, is: C?0.0040%, Si:0.1˜0.8%, Al:0.002˜1.0%, Mn:0.10˜1.50%, P:?0.2%, Sb:0.04˜0.08%, S?0.0030%, N?0.0020%, Ti?0.0020%, and the rest is Fe and unavoidable inclusions. The molten steel is then cast into billets which are hot-rolled into a hot-rolled product. The heating temperature for the billet is 1100°˜1150° and the finish-rolling temperature is 860°˜920°. The hot-rolled product is then air cooled for a period of time within a range determined by air cooling time t: (2+30xSb %)s?t?7 s. The hot-rolled product is reeled at a temperature ?720° and cold-rolled to form cold-rolled plate with a target thickness at a reduction ratio of 70˜78% followed by heating up the cold-rolled plate to 800˜1000° at heating rate of ?15°/s, and holding time of 10 s˜25 s.

Abstract: Disclosed are a non-oriented electrical steel plate with low iron loss and high magnetic conductivity and a manufacturing process therefor. The casting blank of the steel plate comprises the following components: Si: 0.1-2.0 wt %, Al: 0.1-1.0 wt %, Mn: 0.10-1.0 wt %, C: ?0.005 wt %, P: ?0.2 wt %, S: ?0.005 wt %, N: ?0.005 wt %, the balance being Fe and unavoidable impurities. The magnetic conductivity of the steel plate meets the following relationship formula: ?10+?13+?15?13982?586.5P15/50; ?10+?13+?15?10000, wherein P15/50 is the iron loss at a magnetic induction intensity of 1.5 T at 50 Hz; ?10, ?13, and ?15 are relative magnetic conductivities at induction intensities of 1.0 T, 1.3 T, and 1.5 T at 50 Hz, respectively. The steel plate can be used for manufacturing highly effective and ultra-highly effective electric motors.

Abstract: The present disclosure provides an automated bioprocessing device, which may comprises a processing machine, one or more removable washing cartridges. The removable washing cartridge may comprise a shell, a sample holder, a washing basin, a waste container, a reagent container, a rotation mechanism, and a poking mechanism. The processing machine may comprise a motor, which may provide power to the inserted removable washing cartridge.

Abstract: The present disclosure is directed to peptide-based compounds, their derivatives, pharmaceutically acceptable salts, solvates and hydrates thereof. The compounds and compositions of the present disclosure may inhibit neurotransmitter release and muscle contraction as a treatment for wrinkles. The compounds of the disclosure may be used for pathological neuronal exocytosis-mediated cosmetic and/or therapeutic purposes.

Abstract: A spring structure includes a support body, a first support rod, a second support rod, a first spring, a second spring, a first mounting member, and a second mounting member used for connecting to a lower shell of the slide phone. An installation hole running through the support body is disposed on the support body. One end of the first support rod is connected to the first mounting member and the other end is inserted in the installation hole of the support body. The first support rod may move along the installation hole and is sleeved with the first spring. One end of the second support rod is connected to the second mounting member and the other end is inserted in the installation hole of the support body.

Abstract: The present disclosure provides an automated bioprocessing device, which may comprises a processing machine, one or more removable washing cartridges. The removable washing cartridge may comprise a shell, a sample holder, a washing basin, a waste container, a reagent container, a rotation mechanism, and a poking mechanism. The processing machine may comprise a motor, which may provide power to the inserted removable washing cartridge.

Abstract: The present invention provides devices, apparatuses and methods for automated processing of biological samples. This invention provides automated devices and automated methods of sequentially treating a biological sample with processing fluids in more than one washing basin. In some embodiments, the invention provides automated devices and automated methods of western blot processing. In some embodiments, the invention provides automated devices and automated methods of Southern blot processing. In some embodiments, the invention provides automated devices and automated methods of northern blot processing. In some embodiments, the invention provides automated devices and automated methods of staining biomolecules on solid supports. In some embodiments, the invention provides automated devices and automated methods of nucleic acid separation and isolation.

Abstract: The present invention provides a non-oriented silicon steel with excellent magnetic properties and a manufacturing process therefor. During the manufacturing process of the present invention, the temperature T of the molten steel of steel tapped from a converter during steelmaking and the carbon content [C] and the free oxygen content [O] comply with the following formula: 7.27×103?[O][C]e(?5000/T)?2.99×104, and the final annealing step uses tension annealing at a low temperature for a short time. A non-oriented silicon steel with a low iron loss, and excellent anisotropy of iron loss can be obtained by means of the manufacturing process of the present invention.

Abstract: A method for producing a silicon steel normalizing substrate comprises: steelmaking, hot rolling and normalizing steps. The normalizing step uses a normalizing furnace having a nonoxidizing heating furnace section. The nonoxidizing heating furnace section comprises more than 3 furnace zones. An energy investment ratio of the furnace zones used in the nonoxidizing heating furnace section is adjusted, so as to control an excess coefficient ? of the nonoxidizing heating furnace section to be within a range of 0.8??<1.0.

Abstract: An unoriented silicon steel having high magnetic conductivity and low iron loss at a working magnetic density of 1.0-1.5 T and method for manufacturing same. By proper deoxidation control in a RH refining and high-temperature treatment for a short time in a normalizing step, the method can reduce the amount of inclusions in the silicon steel and improve grain shape, so as to improve the magnetic conductivity and iron loss of the unoriented silicon steel at a magnetic density of 1.0-1.5 T.

Abstract: Disclosed are a non-oriented electrical steel plate with low iron loss and high magnetic conductivity and a manufacturing process therefor. The casting blank of the steel plate comprises the following components: Si: 0.1-2.0 wt %, Al: 0.1-1.0 wt %, Mn: 0.10-1.0 wt %, C: ?0.005 wt %, P: ?0.2 wt %, S: ?0.005 wt %, N: ?0.005 wt %, the balance being Fe and unavoidable impurities. The magnetic conductivity of the steel plate meets the following relationship formula: ?10+?13+?15?13982?586.5P15/50; ?10+?13+?15?10000, wherein P15/50 is the iron loss at a magnetic induction intensity of 1.5 T at 50 Hz; ?10, ?13, and ?15 are relative magnetic conductivities at induction intensities of 1.0 T, 1.3 T, and 1.5 T at 50 Hz, respectively. The steel plate can be used for manufacturing highly effective and ultra-highly effective electric motors.

Abstract: The present disclosure is directed to peptide-based compounds, their derivatives, pharmaceutically acceptable salts, solvates and hydrates thereof. The compounds and compositions of the present disclosure may inhibit neurotransmitter release and muscle contraction as a treatment for wrinkles. The compounds of the disclosure may be used for pathological neuronal exocytosis-mediated cosmetic and/or therapeutic purposes.

Abstract: A spring structure includes a support body, a first support rod, a second support rod, a first spring, a second spring, a first mounting member, and a second mounting member used for connecting to a lower shell of the slide phone. An installation hole running through the support body is disposed on the support body. One end of the first support rod is connected to the first mounting member and the other end is inserted in the installation hole of the support body. The first support rod may move along the installation hole and is sleeved with the first spring. One end of the second support rod is connected to the second mounting member and the other end is inserted in the installation hole of the support body.

Abstract: The present invention provides devices, apparatuses and methods for automated processing of biological samples. This invention provides automated devices and automated methods of sequentially treating a biological sample with processing fluids in more than one washing basin. In some embodiments, the invention provides automated devices and automated methods of western blot processing. In some embodiments, the invention provides automated devices and automated methods of Southern blot processing. In some embodiments, the invention provides automated devices and automated methods of northern blot processing. In some embodiments, the invention provides automated devices and automated methods of staining biomolecules on solid supports. In some embodiments, the invention provides automated devices and automated methods of nucleic acid separation and isolation.

Abstract: A manufacture method of high-efficiency non-oriented silicon steel with excellent magnetic property, which comprises the following steps: 1) smelting and casting; chemical compositions of non-oriented silicon steel, by weight percent, are: C?0.0040%, Si: 0.1˜0.8%, Al: 0.002˜1.0%, Mn: 0.10˜1.50%, P: ?0.2%, Sb: 0.04˜0.08%, S?0.0030%, N?0.0020%, Ti?0.0020%, and the rest is Fe and unavoidable inclusions; molten steel in accordance with the above compositions is smelted and then casted into billets; 2) hot-rolling and pickling; heating temperature for slab is 1100° C.˜1150° C. and finish-rolling temperature is 860° C.˜920° C.; after rolling, the hot-rolled product is air cooled, during which air cooling time t: (2+30×Sb %)s?t?7 s; thereafter reeling at a temperature ?720° C. ; 3) cold-rolling; rolling to form cold-rolled plate with target thickness at a reduction ratio of 70˜18%; 4) annealing; heating up the cold-rolled plate to 800˜1000° C. at heating rate of ?15° C./s, and holding time is 10 s˜25 s.

Abstract: A zoom lens includes a first lens, a first lens barrel, a shutter assembly, and a guide barrel. The first lens barrel houses the first lens. The shutter assembly is positioned on a distal end of the first lens barrel toward an object side of the zoom lens. The guide barrel is received in the first lens barrel and configured for guiding the first lens barrel to move along the optical axis of the zoom lens.

Abstract: The present invention provides a series of cyclin-dependent protein kinases (Cdks) inhibitors, Scutellaria flavonoid organic amine derivatives, synthesis and use thereof. The preparation method is as follows: taking Baicalein (or Wogonin) from Scutellaria baicalensis as lead compound, mixting it with formaldehyde solution and organic amine compounds based on the molar ratio of 1:1-1.2:1-1.2, adding methanol of duplicate weight than baicalein and reacting at 50-70° C., filtering the sediment and washing and then drying so as to get the product with a content of not less than 97% (weight). Similar to Flavopiridol and P276-00, the activity of baicalein organic amine derivatives inhibiting Cdks has an increase of 50 times compared with that of Baicalin. It can selectively induce apoptosis of the proliferative phase cancer cells, which has scarcely any influence to the normal structure, and it belongs to anticancer drugs of cell cycle inhibitor kind.