Patents by Inventor Liangfeng JIANG

Liangfeng JIANG has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ANTI-MASP-2 ANTIBODY, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF
    Publication number: 20250066508
    Abstract: The present invention provides an antibody combined with human MASP-2, a preparation method therefor, and an application thereof. The monoclonal antibody of the present invention specifically binds to a MASP-2 antigen, and has high affinity, high specificity and high biological activity, thus having good clinical application prospects.
    Type: Application
    Filed: December 21, 2022
    Publication date: February 27, 2025
    Inventors: Zhenping ZHU, Chen ZHOU, Haomin HUANG, Jie ZHAO, Liangfeng JIANG, Rui XING
  • Antibodies binding to human IL-4R, preparation method therefor and use thereof
    Patent number: 11667717
    Abstract: Disclosed are antibodies binding to human IL-4R, having identical variable regions and different constant regions, wherein the variable regions can specifically bind to human IL-4R, and the constant regions affect the activity of the whole antibody through an amino acid site mutation. The above-mentioned antibodies can be used to treat diseases related to IL-4R overexpression, such as atopic dermatitis, asthma, etc., and thus possesses good clinical application prospects.
    Type: Grant
    Filed: August 20, 2019
    Date of Patent: June 6, 2023
    Assignee: SUNSHINE GUOJIAN PHARMACEUTICAL (SHANGHAI) CO., LTD.
    Inventors: Jie Zhao, Liangfeng Jiang, Chen Chen, Huiling Wu, Yuping Huang, Haomin Huang, Zhenping Zhu
  • Monoclonal antibody binding to human IL-5, preparation method therefor and use thereof
    Patent number: 11370836
    Abstract: Disclosed is a monoclonal antibody that binds to human IL-5. The monoclonal antibody that binds to human IL-5 has a good biological activity for inhibiting TF-1 cell proliferation induced by IL-5 and blocking the interaction between IL-5 and IL-5RA, has a different antigen epitope from the known anti-human IL-5 antibody, can be used for preparing drugs for treating diseases mediated by the over-expression of eosinophilic granulocytes (such as asthma), and has a good clinical application prospect.
    Type: Grant
    Filed: November 30, 2018
    Date of Patent: June 28, 2022
    Assignee: SUNSHINE GUOJIAN PHARMACEUTICAL (SHANGHAI) CO., LTD.
    Inventors: Jie Zhao, Haomin Huang, Zhenping Zhu, Liangfeng Jiang
  • ANTIBODIES BINDING TO HUMAN IL-4R, PREPARATION METHOD THEREFOR AND USE THEREOF
    Publication number: 20210206861
    Abstract: Disclosed are antibodies binding to human IL-4R, having identical variable regions and different constant regions, wherein the variable regions can specifically bind to human IL-4R, and the constant regions affect the activity of the whole antibody through an amino acid site mutation. The above-mentioned antibodies can be used to treat diseases related to IL-4R overexpression, such as atopic dermatitis, asthma, etc., and thus possesses good clinical application prospects.
    Type: Application
    Filed: August 20, 2019
    Publication date: July 8, 2021
    Inventors: Jie ZHAO, Liangfeng JIANG, Chen CHEN, Huiling WU, Yuping HUANG, Haomin HUANG, Zhenping ZHU
  • MONOCLONAL ANTIBODY BINDING TO HUMAN IL-5, PREPARATION METHOD THEREFOR AND USE THEREOF
    Publication number: 20210171621
    Abstract: Disclosed is a monoclonal antibody that binds to human IL-5. The monoclonal antibody that binds to human IL-5 has a good biological activity for inhibiting TF-1 cell proliferation induced by IL-5 and blocking the interaction between IL-5 and IL-5RA, has a different antigen epitope from the known anti-human IL-5 antibody, can be used for preparing drugs for treating diseases mediated by the over-expression of eosinophilic granulocytes (such as asthma), and has a good clinical application prospect.
    Type: Application
    Filed: November 30, 2018
    Publication date: June 10, 2021
    Inventors: Jie ZHAO, Haomin HUANG, Zhenping ZHU, Liangfeng JIANG