Patents by Inventor Lianghong Zheng

Lianghong Zheng has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230348992
    Abstract: Disclosed herein, in certain embodiments, are methods and kits for diagnosing a subject as having hepatocellular carcinoma (HCC) or lung cancer. In some instances, also described herein are methods of determining the prognosis of the subject having HCC or lung cancer. In additional instances, described herein are methods of determining the specific staging of HCC or lung cancer in a subject.
    Type: Application
    Filed: February 3, 2023
    Publication date: November 2, 2023
    Inventors: Kang ZHANG, Rui HOU, Lianghong ZHENG
  • Patent number: 11396678
    Abstract: Disclosed herein are methods and kits for identifying a subject as having breast cancer. Also provided herein are methods and kits for determining the prognosis of a subject having breast cancer and for determining the progression of breast cancer in a subject.
    Type: Grant
    Filed: July 6, 2017
    Date of Patent: July 26, 2022
    Assignees: The Regent of the University of California, YouHealth Oncotech, Limited
    Inventors: Kang Zhang, Rui Hou, Lianghong Zheng
  • Publication number: 20220165418
    Abstract: Disclosed herein are systems, methods, devices, and media for carrying out detection of ophthalmic and systemic diseases and disorders. Deep learning algorithms enable the automated analysis of ophthalmic images such as retinal scans to generate accurate detection of various diseases and disorders. Point-of-care implementations allow for rapid and efficient detection outside of the clinical setting.
    Type: Application
    Filed: September 29, 2021
    Publication date: May 26, 2022
    Inventors: Zhihuan LI, Lianghong ZHENG, Kang ZHANG
  • Patent number: 11279978
    Abstract: Disclosed herein are methods of increasing the expression rate of epigenetic markers such as ELOVL2, KLF14, and PENK with administration of a therapeutic agent (e.g., vitamin C or its derivatives, analogs, metabolites, prodrugs, or pharmaceutically acceptable salts thereof). Also described herein are methods of modulating the methylation pattern of epigenetic markers such as ELOVL2, KLF14, and PENK with administration of a therapeutic agent (e.g., vitamin C or its derivatives, analogs, metabolites, prodrugs, or pharmaceutically acceptable salts thereof).
    Type: Grant
    Filed: November 19, 2018
    Date of Patent: March 22, 2022
    Assignees: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA, YouHealth Biotech, Limited
    Inventors: Kang Zhang, Rui Hou, Lianghong Zheng
  • Publication number: 20210375460
    Abstract: Disclosed herein are systems, methods, devices, and media for carrying out diagnosis of myopia onset and progression. Machine learning algorithms enable the automated analysis of relevant features to generate predictions. Also disclosed are treatment methods incorporating the machine learning algorithms to identify suitable treatments and predict treatment efficacy.
    Type: Application
    Filed: April 26, 2021
    Publication date: December 2, 2021
    Inventors: Zhihuan LI, Rui HOU, Lianghong ZHENG
  • Publication number: 20210343411
    Abstract: Disclosed herein are methods and systems for Artificial Intelligence (AI)-based methods for performing medical diagnosis of diseases and conditions. An automated natural language processing (NLP) system performs deep learning techniques to extract clinically relevant information from electronic health records (EHRs). This framework provides a high diagnostic accuracy that demonstrates a successful AI-based method for systematic disease diagnosis and management.
    Type: Application
    Filed: December 29, 2020
    Publication date: November 4, 2021
    Inventors: Kang ZHANG, Zhihuan LI, Lianghong ZHENG
  • Publication number: 20210115518
    Abstract: Disclosed herein are methods and kits for identifying a subject as having leukemia. Also provided herein are methods and kits for determining a leukemia subtype in subject. Further provided herein are methods and kits for determining the prognosis of a subject having leukemia and for determining the progression of leukemia in a subject.
    Type: Application
    Filed: June 22, 2020
    Publication date: April 22, 2021
    Inventors: Kang ZHANG, Rui HOU, Lianghong ZHENG
  • Publication number: 20210042916
    Abstract: Disclosed herein are systems, methods, devices, and media for carrying out medical diagnosis of diseases and conditions using artificial intelligence or machine learning approaches. Deep learning algorithms enable the automated analysis of medical images such as X-rays to generate predictions of comparable accuracy to clinical experts for various diseases and conditions including those afflicting the lung such as pneumonia.
    Type: Application
    Filed: February 7, 2019
    Publication date: February 11, 2021
    Inventors: Kang ZHANG, Rui HOU, Lianghong ZHENG
  • Patent number: 10829821
    Abstract: Disclosed herein are methods and kits for identifying a subject as having leukemia. Also provided herein are methods and kits for determining a leukemia subtype in subject. Further provided herein are methods and kits for determining the prognosis of a subject having leukemia and for determining the progression of leukemia in a subject.
    Type: Grant
    Filed: August 3, 2018
    Date of Patent: November 10, 2020
    Assignees: YOUHEALTH ONCOTECH, LIMITED, THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Kang Zhang, Rui Hou, Lianghong Zheng
  • Publication number: 20200299776
    Abstract: Disclosed herein are methods and kits for identifying a subject as having esophagus cancer, pancreatic cancer, or stomach cancer. Also provided herein are methods and kits for generating the methylation profile of a biomarker associated with esophagus cancer, pancreatic cancer, or stomach cancer.
    Type: Application
    Filed: December 26, 2019
    Publication date: September 24, 2020
    Inventors: Kang ZHANG, Rui HOU, Lianghong ZHENG
  • Publication number: 20200277677
    Abstract: Disclosed herein are methods, probes, and kits for diagnosing the presence of cancer and/or a cancer type in a subject.
    Type: Application
    Filed: October 5, 2018
    Publication date: September 3, 2020
    Applicants: YouHealth Oncotech, Limited, The Regents of the University of California
    Inventors: Kang ZHANG, Rui HOU, Lianghong ZHENG, Gen LI
  • Publication number: 20200263256
    Abstract: Disclosed herein, in certain embodiments, are methods and kits for diagnosing a subject as having hepatocellular carcinoma (HCC) or lung cancer. In some instances, also described herein are methods of determining the prognosis of the subject having HCC or lung cancer. In additional instances, described herein are methods of determining the specific staging of HCC or lung cancer in a subject.
    Type: Application
    Filed: November 1, 2019
    Publication date: August 20, 2020
    Inventors: Kang ZHANG, Rui HOU, Lianghong ZHENG
  • Patent number: 10722180
    Abstract: Disclosed herein are systems, methods, devices, and media for carrying out medical diagnosis of ophthalmic diseases and conditions. Deep learning algorithms enable the automated analysis of ophthalmic images to generate predictions of comparable accuracy to clinical experts.
    Type: Grant
    Filed: October 15, 2018
    Date of Patent: July 28, 2020
    Inventors: Kang Zhang, Rui Hou, Lianghong Zheng
  • Patent number: 10544467
    Abstract: Disclosed herein are methods and kits for identifying a subject as having esophagus cancer, pancreatic cancer, or stomach cancer. Also provided herein are methods and kits for generating the methylation profile of a biomarker associated with esophagus cancer, pancreatic cancer, or stomach cancer.
    Type: Grant
    Filed: December 12, 2017
    Date of Patent: January 28, 2020
    Assignees: YouHealth Oncotech, Limited, The Regents of the University of California
    Inventors: Kang Zhang, Rui Hou, Lianghong Zheng
  • Patent number: 10513739
    Abstract: Disclosed herein, in certain embodiments, are methods and kits for diagnosing a subject as having hepatocellular carcinoma (HCC) or lung cancer. In some instances, also described herein are methods of determining the prognosis of the subject having HCC or lung cancer. In additional instances, described herein are methods of determining the specific staging of HCC or lung cancer in a subject.
    Type: Grant
    Filed: March 2, 2018
    Date of Patent: December 24, 2019
    Assignees: YouHealth Oncotech, Limited, The Regents of the University of California
    Inventors: Kang Zhang, Rui Hou, Lianghong Zheng
  • Publication number: 20190360052
    Abstract: Disclosed herein are methods and kits for identifying a subject as having breast cancer. Also provided herein are methods and kits for determining the prognosis of a subject having breast cancer and for determining the progression of breast cancer in a subject.
    Type: Application
    Filed: July 6, 2017
    Publication date: November 28, 2019
    Inventors: Kang ZHANG, Rui HOU, Lianghong ZHENG
  • Publication number: 20190345560
    Abstract: Disclosed herein are methods and kits for identifying a subject as having lung cancer. Also provided herein are methods and kits for determining the prognosis of a subject having lung cancer and for determining the progression of lung cancer in a subject.
    Type: Application
    Filed: July 6, 2017
    Publication date: November 14, 2019
    Inventors: Kang ZHANG, Rui HOU, Lianghong ZHENG
  • Publication number: 20190300965
    Abstract: Disclosed herein are methods and kits for identifying a subject as having liver cancer. Also provided herein are methods and kits for determining the prognosis of a subject having liver cancer and for determining the progression of liver cancer in a subject.
    Type: Application
    Filed: July 6, 2017
    Publication date: October 3, 2019
    Inventors: Kang ZHANG, Rui HOU, Lianghong ZHENG
  • Publication number: 20190300964
    Abstract: Disclosed herein are methods and kits for identifying a subject as having colon cancer. Also provided herein are methods and kits for determining the prognosis of a subject having colon cancer and for determining the progression of colon cancer in a subject.
    Type: Application
    Filed: July 6, 2017
    Publication date: October 3, 2019
    Inventors: Kang ZHANG, Rui HOU, Lianghong ZHENG
  • Publication number: 20190177796
    Abstract: Disclosed herein are methods of increasing the expression rate of epigenetic markers such as ELOVL2, KLF14, and PENK with administration of a therapeutic agent (e.g., vitamin C or its derivatives, analogs, metabolites, prodrugs, or pharmaceutically acceptable salts thereof). Also described herein are methods of modulating the methylation pattern of epigenetic markers such as ELOVL2, KLF14, and PENK with administration of a therapeutic agent (e.g., vitamin C or its derivatives, analogs, metabolites, prodrugs, or pharmaceutically acceptable salts thereof).
    Type: Application
    Filed: November 19, 2018
    Publication date: June 13, 2019
    Inventors: Kang Zhang, Rui Hou, Lianghong Zheng