Patents by Inventor Liangjun Lu
Liangjun Lu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Patent number: 11874362Abstract: Integrated two-dimensional multi-beam LiDAR transmitter based on the Butler matrix, comprising an tunable laser array, a frequency modulated continuous wave modulator array, an N×N Butler optical matrix network, an N×M optical beam expanding network, an M-path phase shifter array, and an M-path two-dimensional LiDAR emitters.Type: GrantFiled: October 1, 2020Date of Patent: January 16, 2024Assignee: Shanghai Jiao Tong UniversityInventors: Liangjun Lu, Chen Zhu, Linjie Zhou, Jiao Liu, Jianping Chen
-
Patent number: 11733098Abstract: A silicon Fourier transform spectrometer and an optical spectrum reconstruction method are disclosed. The spectrometer includes a waveguide input coupler, cascaded optical switches, unbalanced subwavelength grating (SWG) waveguide pairs, and a germanium silicon detector, where the cascaded optical switches are connected through unbalanced SWG waveguide pairs. The state of the optical switches are adjusted to digitally configure the optical path, so as to constitute a series of unbalanced Mach-Zehnder interferometer (MZI) arrays with different optical path differences, to realize a Fourier transform spectrometer based on spatial heterodyne. The optical spectrum is reconstructed by using a compressed sensing algorithm.Type: GrantFiled: December 23, 2021Date of Patent: August 22, 2023Assignee: Shanghai Jiao Tong UniversityInventors: Liangjun Lu, Junjie Du, Linjie Zhou, Jianping Chen, Jiao Liu
-
Patent number: 11639390Abstract: The present disclosure provides anti-?4?7 antibodies that bind human ?4?7, their methods of making, and their uses to treat patients with HIV infection.Type: GrantFiled: July 16, 2021Date of Patent: May 2, 2023Assignee: AbbVie Inc.Inventors: Jing Min, Teresa (Iok-Chan) Ng, Lorenzo Benatuil, Jacqueline Bixby, Tatyana Dekhtyar, Feng Dong, Axel Hernandez, Jr., Preethi Krishnan, Liangjun Lu, Federico Mensa, Renee Miller, Gautam Sahu
-
Publication number: 20220197106Abstract: A calibration system and related methods for optical phased array chips. The calibration system includes an adjustable mount module, an infrared microscopic observation module, an arrayed driver module, a two-dimensional laser beam scanning module, a photoelectric conversion module and an upper computer, and utilizes computer-vision-enabled positioning and phase error compensation algorithms as software components. Collimated laser is emitted from the target beamforming angle and aimed at the emission aperture of the chip, and is subsequently sampled by the array elements in a reversed injection manner. Based on the reciprocity of light propagation, by maximizing the power reversely output from the bus waveguide of the optical phased array chip, beamforming at the target angle is achieved supported by software implementations of optimization algorithms.Type: ApplicationFiled: December 24, 2021Publication date: June 23, 2022Inventors: Liangjun LU, Weihan XU, Linjie ZHOU, Jianping CHEN, Jiao LIU
-
Publication number: 20220187129Abstract: A silicon Fourier transform spectrometer and an optical spectrum reconstruction method are disclosed. The spectrometer includes a waveguide input coupler, cascaded optical switches, unbalanced subwavelength grating (SWG) waveguide pairs, and a germanium silicon detector, where the cascaded optical switches are connected through unbalanced SWG waveguide pairs. The state of the optical switches are adjusted to digitally configure the optical path, so as to constitute a series of unbalanced Mach-Zehnder interferometer (MZI) arrays with different optical path differences, to realize a Fourier transform spectrometer based on spatial heterodyne. The optical spectrum is reconstructed by using a compressed sensing algorithm.Type: ApplicationFiled: December 23, 2021Publication date: June 16, 2022Inventors: Liangjun LU, Junjie DU, Linjie ZHOU, Jianping CHEN, Jiao LIU
-
Patent number: 11333826Abstract: A silicon- and optical phased array-based integrated optically adjustable delay line, comprising, an optical phased array transmitting unit, a slab waveguide transmitting unit, and an optical phased array receiving unit that are sequentially arranged. By the optical phase control transmitting unit, the phase difference between channels is regulated and controlled via a phase shifter to change a far-field interference light spot and form a wave beam with directivity to regulate and control an incident angle of an optical signal entering the slab waveguide, thus changing the propagation path length of the optical signal. Finally, the optical signal is received by a corresponding optical phased array receiving unit to obtain different delay amounts. Large adjustable delay amount is realized and the delay line has the advantages of simple structure and control and high integration level with high application value in optical communication and microwave photonic and optical signal processing.Type: GrantFiled: September 30, 2020Date of Patent: May 17, 2022Assignee: Shanghai Jiao Tong UniversityInventors: Linjie Zhou, Wensheng Shan, Weihan Xu, Liangjun Lu, Jianping Chen, Jiao Liu
-
Publication number: 20220017624Abstract: The present disclosure provides anti-?4?7 antibodies that bind human ?4?7, their methods of making, and their uses to treat patients with HIV infection.Type: ApplicationFiled: July 16, 2021Publication date: January 20, 2022Inventors: Jing Min, Teresa (Iok-Chan) Ng, Lorenzo Benatuil, Jacqueline Bixby, Tatyana Dekhtyar, Feng Dong, Axel Hernandez, Jr., Preethi Krishnan, Liangjun Lu, Federico Mensa, Renee Miller, Gautam Sahu
-
Publication number: 20210181310Abstract: A chip-scale silicon-based hybrid-integrated LiDAR system, wherein a transmitting end thereof sequentially comprises a narrow-linewidth tunable laser source, a silicon-nitride-based beam splitter, a silicon-based phase shifter array and a silicon-nitride-based unidirectional transmitting antenna array w.r.t the optical path. Based on the principle of reciprocity of light propagation, the receiving end thereof sequentially comprises a silicon nitride unidirectional receiving antenna array, a silicon nitride beam splitter and a silicon-based coherent receiving module. It also comprises a backup system and an electric controller as the driver of the phase shifters and the processing module. Modules on the silicon platform and the silicon nitride platform are monolithic integrated in a multilayer sandwiched fashion by means of a tapered silicon/silicon nitride evanescent inter-layer coupler; and a gain chip in the tunable laser module and a silicon nitride waveguide are hybrid-integrated by horizontal coupling.Type: ApplicationFiled: February 8, 2021Publication date: June 17, 2021Inventors: Liangjun LU, Weihan XU, Linjie ZHOU, Jiao LIU, Jianping CHEN
-
Publication number: 20210026068Abstract: A silicon- and optical phased array-based integrated optically adjustable delay line, comprising, an optical phased array transmitting unit, a slab waveguide transmitting unit, and an optical phased array receiving unit that are sequentially arranged. By the optical phase control transmitting unit, the phase difference between channels is regulated and controlled via a phase shifter to change a far-field interference light spot and form a wave beam with directivity to regulate and control an incident angle of an optical signal entering the slab waveguide, thus changing the propagation path length of the optical signal. Finally, the optical signal is received by a corresponding optical phased array receiving unit to obtain different delay amounts. Large adjustable delay amount is realized and the delay line has the advantages of simple structure and control and high integration level with high application value in optical communication and microwave photonic and optical signal processing.Type: ApplicationFiled: September 30, 2020Publication date: January 28, 2021Inventors: Linjie ZHOU, Wensheng SHAN, Weihan XU, Liangjun LU, Jianping CHEN, Jiao LIU
-
Publication number: 20210018603Abstract: Integrated two-dimensional multi-beam LiDAR transmitter based on the Butler matrix, comprising an tunable laser array, a frequency modulated continuous wave modulator array, an N×N Butler optical matrix network, an N×M optical beam expanding network, an M-path phase shifter array, and an M-path two-dimensional LiDAR emitters.Type: ApplicationFiled: October 1, 2020Publication date: January 21, 2021Inventors: Liangjun LU, Chen ZHU, Linjie ZHOU, Jiao LIU, Jianping CHEN
-
Publication number: 20210018599Abstract: A three-dimensional scanning LiDAR based on one-dimensional optical phased arrays comprises a transmitting end, a coherent receiving end and an incoherent receiving end, wherein the transmitting end, the coherent receiving end and the incoherent receiving end are all one-dimensional arrays. A phase control complexity of the three-dimensional scanning phased array is reduced, and a tunable laser with high cost and a grating array antenna with large crosstalk are avoided. The LiDAR provides pure solid-state three-dimensional scanning in speed and integration level and is highly practical.Type: ApplicationFiled: September 30, 2020Publication date: January 21, 2021Inventors: Liangjun Lu, Weihan Xu, Linjie Zhou, Jianping Chen, Jiao Liu
-
Publication number: 20150119400Abstract: Pan-genotypic HCV inhibitors are described. This invention also relates to methods of using these inhibitors to treat HCV infection.Type: ApplicationFiled: October 24, 2014Publication date: April 30, 2015Inventors: Iok C. Ng, Liangjun Lu, Tanya Dekhtyar, Thomas Reisch, Rakesh L. Tripathi, Ron Pithawalla, Christine A. Collins, Tami J. Pilot-Matias
-
Publication number: 20150119319Abstract: The present invention relates to novel fluorinated macrocyclic compounds and methods of treating a hepatitis C infection in a subject in need of such therapy with said macrocyclic compounds. The present invention further relates to pharmaceutical compositions comprising the compounds of the present invention, or pharmaceutically acceptable salts, esters, or prodrugs thereof, in combination with a pharmaceutically acceptable carrier or excipient.Type: ApplicationFiled: January 2, 2015Publication date: April 30, 2015Inventors: Keith F. McDaniel, Hui-Ju Chen, Ming Yeung, Timothy Middleton, Liangjun Lu, Kevin Kurtz
-
Patent number: 8937041Abstract: The present invention relates to novel fluorinated macrocyclic compounds and methods of treating a hepatitis C infection in a subject in need of such therapy with said macrocyclic compounds. The present invention further relates to pharmaceutical compositions comprising the compounds of the present invention, or pharmaceutically acceptable salts, esters, or prodrugs thereof, in combination with a pharmaceutically acceptable carrier or excipient.Type: GrantFiled: December 29, 2011Date of Patent: January 20, 2015Assignee: AbbVie, Inc.Inventors: Keith F. McDaniel, Hui-Ju Chen, Ming Yeung, Timothy Middleton, Liangjun Lu, Kevin Kurtz
-
Patent number: 8338605Abstract: Compounds effective in inhibiting replication of Hepatitis C virus (“HCV”) or other viruses are disclosed. This invention is also directed to compositions comprising such compounds, co-formulation or co-administration of such compounds with other anti-viral or therapeutic agents, processes and intermediates for the syntheses of such compounds, and methods of using such compounds for the treatment of HCV or other viral infections.Type: GrantFiled: June 17, 2010Date of Patent: December 25, 2012Assignee: Abbott LaboratoriesInventors: Todd W. Rockway, David A. Betebenner, Allan C. Krueger, Nobuhiko Iwasaki, Curt S. Cooper, David D. Anderson, Dale J. Kempf, Darold L. Madigan, Christopher E. Motter, Jason P. Shanley, Michael D. Tufano, Rolf Wagner, Rong Zhang, Akteruzzaman Molla, Hongmei Mo, Tami J. Pilot-Matias, Sherie V. L. Masse, Robert J. Carrick, Wenping He, Liangjun Lu
-
Patent number: 8236950Abstract: Compounds effective in inhibiting replication of Hepatitis C virus (“HCV”) or other viruses are disclosed. This invention is also directed to compositions comprising such compounds, co-formulation or co-administration of such compounds with other anti-viral or therapeutic agents, processes and intermediates for the syntheses of such compounds, and methods of using such compounds for the treatment of HCV or other viral infections.Type: GrantFiled: December 19, 2007Date of Patent: August 7, 2012Assignee: Abbott LaboratoriesInventors: David A. Betebenner, Clarence J. Maring, Todd W. Rockway, Curt S. Cooper, David D. Anderson, Rolf Wagner, Rong Zhang, Akhteruzzaman Molla, Hongmei Mo, Tami J. Pilot-Matias, Sherie V L. Masse, Robert J. Carrick, Wenping He, Liangjun Lu
-
Publication number: 20120172291Abstract: The present invention relates to novel fluorinated macrocyclic compounds and methods of treating a hepatitis C infection in a subject in need of such therapy with said macrocyclic compounds. The present invention further relates to pharmaceutical compositions comprising the compounds of the present invention, or pharmaceutically acceptable salts, esters, or prodrugs thereof, in combination with a pharmaceutically acceptable carrier or excipient.Type: ApplicationFiled: December 29, 2011Publication date: July 5, 2012Inventors: Keith F. McDaniel, Hui-Ju Chen, Ming Yeung, Timothy Middleton, Liangjun Lu, Kevin Kurtz
-
Publication number: 20110160233Abstract: Compounds effective in inhibiting replication of Hepatitis C virus (“HCV”) or other viruses are disclosed. This invention is also directed to compositions comprising such compounds, co-formulation or co-administration of such compounds with other anti-viral or therapeutic agents, processes and intermediates for the syntheses of such compounds, and methods of using such compounds for the treatment of HCV or other viral infections.Type: ApplicationFiled: December 19, 2007Publication date: June 30, 2011Applicant: ABBOTT LABORATORIESInventors: David A. Betebenner, Clarence J. Maring, Todd W. Rockway, Curt S. Cooper, David D. Anderson, Rolf Wagner, Rong Zhang, Akhteruzzaman Molla, Hongmei Mo, Tami J. Pilot-Matias, Sherie VL. Masse, Robert J. Carrick, Wenping He, Liangjun Lu
-
Patent number: 7915411Abstract: Compounds effective in inhibiting replication of Hepatitis C virus (“HCV”) or other viruses are disclosed. This invention is also directed to compositions comprising such compounds, co-formulation or co-administration of such compounds with other anti-viral or therapeutic agents, processes and intermediates for the syntheses of such compounds, and methods of using such compounds for the treatment of HCV or other viral infections.Type: GrantFiled: December 20, 2006Date of Patent: March 29, 2011Assignee: Abbott LaboratoriesInventors: David A. Betebenner, David A. DeGoey, Clarence J. Maring, Allan C. Krueger, Nobuhiko Iwasaki, Todd W. Rockway, Curt S. Cooper, David D. Anderson, Pamela L. Donner, Brian E. Green, Dale J. Kempf, Dachun Liu, Keith F. McDaniel, Darold L. Madigan, Christopher E. Motter, John K. Pratt, Jason P. Shanley, Michael D. Tufano, Rolf Wagner, Rong Zhang, Akhteruzzaman Molla, Hongmei Mo, Tami J. Pilot-Matias, Sherie V L. Masse, Robert J. Carrick, Wenping He, Liangjun Lu, David J. Grampovnik
-
Patent number: 7910595Abstract: Compounds effective in inhibiting replication of Hepatitis C virus (“HCV”) or other viruses are disclosed. This invention is also directed to compositions comprising such compounds, co-formulation or co-administration of such compounds with other anti-viral or therapeutic agents, processes and intermediates for the syntheses of such compounds, and methods of using such compounds for the treatment of HCV or other viral infections.Type: GrantFiled: December 20, 2006Date of Patent: March 22, 2011Assignee: Abbott LaboratoriesInventors: David A. Betebenner, David A. DeGoey, Clarence J. Maring, Allan C. Krueger, Nobuhiko Iwasaki, Todd W. Rockway, Curt S. Cooper, David D. Anderson, Pamela L. Donner, Brian E. Green, Dale J. Kempf, Dachun Liu, Keith F. McDaniel, Darold L. Madigan, Christopher E. Motter, John K. Pratt, Jason P. Shanley, Michael D. Tufano, Rolf Wagner, Rong Zhang, Akhteruzzaman Molla, Hongmei Mo, Tami J. Pilot-Matias, Sherie V L. Masse, Robert J. Carrick, Wenping He, Liangjun Lu, David J. Grampovnik