Patents by Inventor Liangliang Sun

Liangliang Sun has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240115844
    Abstract: A particle storage tube (100) used for implanting microparticles into a body in cooperation with a puncture needle (500), and comprising an accommodation portion (1) and a drug delivery portion (2). The accommodation portion (1) is an elongated hollow tube having a channel (10) used to accommodate microparticles (4). One end of the accommodation portion (1) is connected to the drug delivery portion (2), and the other end of the accommodation portion (1) is an open part (11) used to discharge the microparticles out of the particle storage tube (100). The inner diameter of the channel (10) is 1.0-1.8 times the inner diameter of a lumen (502) of the puncture needle (500). An inner chamber (20) of the drug delivery portion (2) is in communication with the channel (10), and is used for delivering liquid medicine (200) to the channel (10).
    Type: Application
    Filed: December 17, 2023
    Publication date: April 11, 2024
    Applicant: SUZHOU YIBEN LIFE TECHNOLOGY CO., LTD
    Inventors: Shaoge GU, Yonghua DONG, Lei JIN, Liangliang ZHAO, Guoxiang SUN
  • Patent number: 11950199
    Abstract: A method performed by a network node for handling a communication session in a wireless communication network. The network node receives from a user equipment (UE) a registration message for re-registering the UE to a session. The network node further verifies the registration message based on registration information previously stored for the UE When verified in response to the reception, transmits back to the UE, a registration response along with a terminating request for a call establishment.
    Type: Grant
    Filed: April 24, 2019
    Date of Patent: April 2, 2024
    Assignee: Telefonaktiebolaget LM Ericsson (publ)
    Inventors: Debashish Pattnaik, Liangliang Guo, Songmao Li, Erqun Sun
  • Publication number: 20240092899
    Abstract: Provided is a bispecific antibody, comprising a first antigen-binding moiety and a second antigen-binding moiety, wherein a paired domain of the first antigen-binding moiety comprises an amino acid sequence of engineered HLA-I ?3 and an amino acid sequence of engineered ?2M. Also provided are an expression method for the bispecific antibody, a polynucleotide encoding the bispecific antibody, a vector and host cell containing the polynucleotide, a pharmaceutical composition containing the bispecific antibody, a fusion protein, and a conjugate.
    Type: Application
    Filed: January 27, 2022
    Publication date: March 21, 2024
    Inventors: Liangliang WANG, Zhengping ZHANG, Congcong SUN, Rongjuan ZHAO, Yimeng LI
  • Publication number: 20240090299
    Abstract: A display panel includes: multiple light-emitting devices arranged on a substrate, each light-emitting device includes a first electrode, multiple light-emitting units and a second electrode sequentially arranged in a direction away from the substrate, a microcavity structure is formed between the first electrode and the second electrode, the light-emitting unit includes a light-emitting layer, light-emission colors of at least two light-emitting layers in the same light-emitting device are different, and at least one light-emitting device includes a cavity length adjusting layer; and a color conversion layer including multiple wavelength conversion units, each wavelength conversion unit corresponds to a light-emitting device having the cavity length adjusting layer, the wavelength conversion unit is arranged on a light outlet side of the light-emitting device, at least one light-emission peak in a light-emission band of the light-emitting device is less than or equal to an intrinsic light-emission peak of a
    Type: Application
    Filed: July 1, 2022
    Publication date: March 14, 2024
    Inventors: Qian JIN, Wei HUANG, Qian SUN, Tianhao LU, Yang LI, Liangliang KANG
  • Publication number: 20240076277
    Abstract: A system and method for preparing epoxy chloropropane is provided in that by coupling three stages of high gravity reactors, the product epoxy chloropropane and water vapor are distilled from a reaction system in form of an azeotrope by adopting a water vapor steam stripping method. Further, by combining the azeotrope with the multiples stages of high gravity reactors, the gas phase mass transfer and the liquid phase mass transfer of the azeotrope are improved aiming at the features of the azeotrope in the reaction system, thus making the overall conversion rate higher. In addition, by combining steam stripping and high gravity, dichloropropanol and alkali solution are rapidly mixed for mass transfer, and the product epoxy chloropropane is rapidly distilled from the reaction system in the form of the azeotrope, such that the reaction proceeds continuously towards the direction of producing epoxy chloropropane, thus significantly improving the conversion rate.
    Type: Application
    Filed: December 24, 2021
    Publication date: March 7, 2024
    Inventors: Liangliang ZHANG, Liyang ZHOU, Guangwen CHU, Bibo XIA, Jianfeng CHEN, Yutu JIANG, Jihong TONG, Baochang SUN, Wei MAO, Yanchun ZHENG
  • Publication number: 20230051334
    Abstract: The present invention discloses a method comprising: A. acquiring the current I0 and I, and setting It1, It2, IR, Vmin, and Vmax. B. acquiring the speed V, and setting the speed VL and VH; C. a mowing motor runs in a low-speed mode, and a self-propelled motor runs at the speed VH; D. when encountering grassy areas, if I0<I<It1, keeping unchanged; if I?It1 and lasting for T1, skipping to E; if I=IR, skipping to G; E. the mowing motor switches to the high-speed mode; F. the mowing motor switches to the low-speed mode, V is switched to VH; G the mowing motor switches to the high-speed mode, V is adjusted to VL; H. the mowing motor stops, the self-propelled motors stop, then retreat and work along the original path, after attempting for M times, if the self-propelled motors stop again, bypassing and skipping to C to continue working.
    Type: Application
    Filed: October 25, 2021
    Publication date: February 16, 2023
    Applicant: ZHEJIANG SAFUN INDUSTRIAL CO., LTD.
    Inventors: Jianbing GUO, Jie LI, Linqiang ZHUANG, Feixiang ZHOU, Changda WU, Li HUANG, Liangliang SUN, Yingying SUN, Xinsen YING
  • Patent number: 11056329
    Abstract: An electrokinetically pumped sheath flow nanospray interface for capillary electrophoresis coupled to negative mode electrospray mass spectrometer is described. At this interface, application of an electric field generates electro-osmotic flow at the interior of a glass emitter having an orifice. Electroosmotic flow pumps liquid around the distal tip of the separation capillary, ensheathing analyte into the electrospray electrolyte. In negative ion mode, negative potential applied to an untreated emitter drives sheath flow away from the emitter orifice, decreasing the stability and efficiency of the spray. In contrast, when the interior of the electrospray emitter is grafted with aminoalkylsilanes, the amines have a positive charge, which reverses electroosmosis and generates stable sheath flow to the emitter orifice under negative potential. Limits of detection were about 150 to 900 attomoles injected.
    Type: Grant
    Filed: December 30, 2016
    Date of Patent: July 6, 2021
    Assignee: University of Notre Dame du Lac
    Inventors: Norman Dovichi, Scott Sarver, Nicole Schiavone, Zhenbin Zhang, Liangliang Sun
  • Publication number: 20200273693
    Abstract: An electrokinetically pumped sheath flow nanospray interface for capillary electrophoresis coupled to negative mode electrospray mass spectrometer is described. At this interface, application of an electric field generates electro-osmotic flow at the interior of a glass emitter having an orifice. Electroosmotic flow pumps liquid around the distal tip of the separation capillary, ensheathing analyte into the electrospray electrolyte. In negative ion mode, negative potential applied to an untreated emitter drives sheath flow away from the emitter orifice, decreasing the stability and efficiency of the spray. In contrast, when the interior of the electrospray emitter is grafted with aminoalkylsilanes, the amines have a positive charge, which reverses electroosmosis and generates stable sheath flow to the emitter orifice under negative potential. Limits of detection were about 150 to 900 attomoles injected.
    Type: Application
    Filed: December 30, 2016
    Publication date: August 27, 2020
    Applicant: University of Notre Dame du Lac
    Inventors: Norman DOVICHI, Scott SARVER, Nicole SCHIAVONE, Zhenbin ZHANG, Liangliang SUN
  • Patent number: 10578580
    Abstract: The invention provides a capillary isoelectric focusing (cIEF) system based on a sandwich injection method for automated chemical mobilization. This system was coupled with an electrokinetically pumped nanoelectrospray interface to a mass spectrometer. The nanoelectrospray emitter employed an acidic sheath electrolyte. To realize automated focusing and mobilization, a plug of ammonium hydroxide was first injected into the capillary, followed by a section of mixed sample and ampholyte. As focusing progressed, the NH3H2O section was titrated to lower pH buffer by the acidic sheath buffer. Chemical mobilization started automatically once the ammonium hydroxide was consumed by the acidic sheath flow electrolyte.
    Type: Grant
    Filed: September 22, 2017
    Date of Patent: March 3, 2020
    Assignee: University of Notre Dame du Lac
    Inventors: Norman Dovichi, Guijie Zhu, Liangliang Sun
  • Patent number: 10416115
    Abstract: A method of coating the inside wall of a capillary with a polymeric material for capillary electrophoresis is disclosed. The method can include introducing a catalyst-free solution of a monomer and initiator, wherein the monomer is present in about 1-10% (w/v) and the initiator is present in 0.1-1% (w/v), into a capillary and thermally initiating polymerization of the monomer thereby providing a capillary comprising an internal polymeric coating for separating, identifying, and quantifying components of an analyte.
    Type: Grant
    Filed: June 20, 2016
    Date of Patent: September 17, 2019
    Assignee: University of Nortre Dame du Lac
    Inventors: Norman Dovichi, Guijie Zhu, Liangliang Sun
  • Publication number: 20190004010
    Abstract: The invention provides a capillary isoelectric focusing (cIEF) system based on a sandwich injection method for automated chemical mobilization. This system was coupled with an electrokinetically pumped nanoelectrospray interface to a mass spectrometer. The nanoelectrospray emitter employed an acidic sheath electrolyte. To realize automated focusing and mobilization, a plug of ammonium hydroxide was first injected into the capillary, followed by a section of mixed sample and ampholyte. As focusing progressed, the NH3H2O section was titrated to lower pH buffer by the acidic sheath buffer. Chemical mobilization started automatically once the ammonium hydroxide was consumed by the acidic sheath flow electrolyte.
    Type: Application
    Filed: September 22, 2017
    Publication date: January 3, 2019
    Applicant: UNIVERSITY OF NOTRE DAME DU LAC
    Inventors: Norman DOVICHI, Guijie ZHU, Liangliang SUN
  • Publication number: 20170363576
    Abstract: The invention provides a novel method of coating the inside of a capillary with a polymeric material. The method can include introducing a catalyst-free solution of a monomer and initiator, wherein the monomer is present in about 1-10% (w/v) and the initiator is present in 0.1-1% (w/v), into a capillary and thermally initiating polymerization of the monomer thereby providing a capillary comprising an internal polymeric coating for separating, identifying, and quantifying components of an analyte.
    Type: Application
    Filed: June 20, 2016
    Publication date: December 21, 2017
    Applicant: University of Notre Dame du Lac
    Inventors: Norman DOVICHI, Guijie ZHU, Liangliang SUN
  • Patent number: 9465014
    Abstract: The invention provides a sheath-flow interface for producing electrospray from a capillary. The electrospray generated by the interface can be used as the source of ions for mass spectrometry. Electrokinetic flow in the interface can move a sheath liquid past the end of a capillary so as to mix with an analyte effluent discharged from the capillary. The sheath liquid and analyte mixture can be directed to an electrospray emitter to generate an electrospray.
    Type: Grant
    Filed: April 5, 2015
    Date of Patent: October 11, 2016
    Assignee: University of Notre Dame du Lac
    Inventors: Norman Dovichi, Liangliang Sun, Guijie Zhu
  • Patent number: 9362102
    Abstract: The invention provides a sheath-flow interface for producing electrospray from a capillary. The electrospray generated by the interface can be used as the source of ions for mass spectrometry. Electrokinetic flow in the interface can move a sheath liquid past the end of a capillary so as to mix with an analyte effluent discharged from the capillary. The sheath liquid and analyte mixture can be directed to an electrospray emitter to generate an electrospray.
    Type: Grant
    Filed: July 7, 2015
    Date of Patent: June 7, 2016
    Assignee: University of Notre Dame du Lac
    Inventors: Norman Dovichi, Liangliang Sun, Guijie Zhu
  • Publication number: 20150311056
    Abstract: The invention provides a sheath-flow interface for producing electrospray from a capillary. The electrospray generated by the interface can be used as the source of ions for mass spectrometry. Electrokinetic flow in the interface can move a sheath liquid past the end of a capillary so as to mix with an analyte effluent discharged from the capillary. The sheath liquid and analyte mixture can be directed to an electrospray emitter to generate an electrospray.
    Type: Application
    Filed: July 7, 2015
    Publication date: October 29, 2015
    Applicant: University of Notre Dame de Lac
    Inventors: Norman Dovichi, Liangliang Sun, Guijie Zhu
  • Publication number: 20150233877
    Abstract: The invention provides a sheath-flow interface for producing electrospray from a capillary. The electrospray generated by the interface can be used as the source of ions for mass spectrometry. Electrokinetic flow in the interface can move a sheath liquid past the end of a capillary so as to mix with an analyte effluent discharged from the capillary. The sheath liquid and analyte mixture can be directed to an electrospray emitter to generate an electrospray.
    Type: Application
    Filed: April 5, 2015
    Publication date: August 20, 2015
    Applicant: UNIVERSITY OF NOTRE DAME DU LAC
    Inventors: Norman Dovichi, Liangliang Sun, Guijie Zhu