Patents by Inventor Liangrang GUO

Liangrang GUO has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for analyzing impurities of oligonucleotide sequence based on high-throughput sequencing and application
    Patent number: 11597922
    Abstract: The present invention provides a method for analyzing impurities of an oligonucleotide sequence based on high-throughput sequencing. The method of the present invention comprises the following steps: constructing a high-throughput sequencing library for analysis of impurities of an oligonucleotide sequence; subjecting the high-throughput sequencing library to high-throughput sequencing, and analyzing the nucleotide sequence components according to the sequencing results; the sequence of the extension primer used in the construction of the high-throughput sequencing library consisting of the DNA molecule set forth in positions 1-22 of SEQ ID NO: 2 and N bases (A, T, C or G) in sequence; and N being an integer greater than or equal to 6.
    Type: Grant
    Filed: August 23, 2018
    Date of Patent: March 7, 2023
    Assignees: SUZHOU GENESCI CO., LTD, SUZHOU GENEPHARMA CO., LTD
    Inventors: Liangrang Guo, Peizhuo Zhang, Lei Yu
  • METHOD FOR ANALYZING IMPURITIES OF OLIGONUCLEOTIDE SEQUENCE BASED ON HIGH-THROUGHPUT SEQUENCING AND APPLICATION
    Publication number: 20210095270
    Abstract: The present invention provides a method for analyzing impurities of an oligonucleotide sequence based on high-throughput sequencing. The method of the present invention comprises the following steps: constructing a high-throughput sequencing library for analysis of impurities of an oligonucleotide sequence; subjecting the high-throughput sequencing library to high-throughput sequencing, and analyzing the nucleotide sequence components according to the sequencing results; the sequence of the extension primer used in the construction of the high-throughput sequencing library consisting of the DNA molecule set forth in positions 1-22 of SEQ ID NO: 2 and N bases (A, T, C or G) in sequence; and N being an integer greater than or equal to 6.
    Type: Application
    Filed: August 23, 2018
    Publication date: April 1, 2021
    Inventors: Liangrang GUO, Peizhuo ZHANG, Lei YU