Patents by Inventor Liangyou WANG

Liangyou WANG has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Chemosynthetic cyclo-hepta modified peptide capable of inhibiting toxin of and use thereof
    Patent number: 10905735
    Abstract: The invention relates to a chemosynthetic cyclo-hepta modified peptide capable of inhibiting toxins of Staphylococcus aureus and a use thereof. The chemosynthetic peptide can specifically inhibit production of the toxins of Staphylococcus aureus by means of the binding of the RNAIII activator protein by a Staphylococcus aureus autocrine. The invention also relates to the use of the chemosynthetic peptide in the pharmaceutical field. The sequence general formula of the chemosynthetic cyclo-hepta modified peptide is CH3—(CH2)m-X-G-(CQHWWHWYC)—(R)n-Y. The results show that the modified peptide can be dissolved well in water and has good activity against the toxins of Staphylococcus aureus.
    Type: Grant
    Filed: April 27, 2017
    Date of Patent: February 2, 2021
    Assignee: ZHONGCHENG INVESTMENT MANAGEMENT (SHANGHAI) CO., LTD
    Inventors: Ningsheng Shao, Guang Yang, Liangyou Wang, Hongmei Ding, Yaping Gao, Shaohua Li, Hui Li, Jie Li, Jie Dong, Wenhui Xia, Xiaoping Liang
  • CHEMOSYNTHETIC CYCLO-HEPTA MODIFIED PEPTIDE CAPABLE OF INHIBITING TOXIN OF STAPHYLOCOCCUS AUREUS AND USE THEREOF
    Publication number: 20190142892
    Abstract: The invention relates to a chemosynthetic cyclo-hepta modified peptide capable of inhibiting toxins of Staphylococcus aureus and a use thereof. The chemosynthetic peptide can specifically inhibit production of the toxins of Staphylococcus aureus by means of the binding of the RNAIII activator protein by a Staphylococcus aureus autocrine. The invention also relates to the use of the chemosynthetic peptide in the pharmaceutical field. The sequence general formula of the chemosynthetic cyclo-hepta modified peptide is CH3—(CH2)m-X-G-(C-Q-H—W—W—H—W—Y—C)—(R)n-Y. The results show that the modified peptide can be dissolved well in water and has good activity against the toxins of Staphylococcus aureus.
    Type: Application
    Filed: April 27, 2017
    Publication date: May 16, 2019
    Applicant: ZHONGCHENG INVESTMENT MANAGEMENT (SHANGHAI) CO., LTD
    Inventors: Ningsheng SHAO, Guang YANG, Liangyou WANG, Hongmei DING, Yaping GAO, Shaohua LI, Hui LI, Jie LI, Jie DONG, Wenhui XIA, Xiaoping LIANG