Patents by Inventor Lian Zhu Liu

Lian Zhu Liu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Cyclohexyl benzamide compounds
    Patent number: 11214562
    Abstract: A compound of the Formula (1) is below provided where R1-R5 are as described in the description and each “*” represents a chiral center.
    Type: Grant
    Filed: July 17, 2017
    Date of Patent: January 4, 2022
    Assignee: ELI LILLY AND COMPANY
    Inventors: Zhi Long Hu, Lian Zhu Liu, Tianwei Ma, Mi Zeng, Haizhen Zhang
  • CYCLOHEXYL BENZAMIDE COMPOUNDS
    Publication number: 20210292302
    Abstract: A compound of the Formula (1) is below provided where R1-R5 are as described in the description and each “*” represents a chiral center.
    Type: Application
    Filed: July 17, 2017
    Publication date: September 23, 2021
    Inventors: Zhi Long Hu, Lian Zhu Liu, Tianwei Ma, Mi Zeng, Haizhen Zhang
  • Imidazolidine compounds
    Patent number: 11124496
    Abstract: The present invention provides a compound of Formula (I) wherein X is selected from the group consisting of (CH2)2— and CH2—CH(CH3)—; Q is selected from the group consisting of C(CH3)2 and Formula (a); or a pharmaceutically acceptable salt thereof; compositions, methods to treat liver disease and NASH.
    Type: Grant
    Filed: August 31, 2018
    Date of Patent: September 21, 2021
    Assignee: Eli Lilly and Company
    Inventors: Lian Zhu Liu, Xiaoqing Wang, Michael Robert Wiley
  • IMIDAZOLIDINE COMPOUNDS
    Publication number: 20210061785
    Abstract: The present invention provides a compound of Formula (I) wherein X is selected from the group consisting of (CH2)2— and CH2—CH(CH3)—; Q is selected from the group consisting of C(CH3)2 and Formula (a); or a pharmaceutically acceptable salt thereof; compositions, methods to treat liver disease and NASH.
    Type: Application
    Filed: August 31, 2018
    Publication date: March 4, 2021
    Inventors: Lian Zhu LIU, Xiaoqing WANG, Michael Robert WILEY
  • Cyclobutyl-imidazolidinone compounds
    Patent number: 10370352
    Abstract: The present invention provides a compound of Formula I wherein Q is selected from the group consisting of —CH(CH3)2 and R is selected from the group consisting of or a pharmaceutically acceptable salt thereof; compositions, methods to treat liver disease and NASH.
    Type: Grant
    Filed: September 6, 2018
    Date of Patent: August 6, 2019
    Assignee: ELI LILLY AND COMPANY
    Inventors: Lian Zhu Liu, Haizhen Zhang, Xiaoqing Wang, Gang Liu
  • Cyclobutyl-Imidazolidinone Compounds
    Publication number: 20190071413
    Abstract: The present invention provides a compound of Formula I wherein Q is selected from the group consisting of —CH(CH3)2 and R is selected from the group consisting of or a pharmaceutically acceptable salt thereof; compositions, methods to treat liver disease and NASH.
    Type: Application
    Filed: September 6, 2018
    Publication date: March 7, 2019
    Inventors: Lian Zhu LIU, Haizhen ZHANG, Xiaoqing WANG, Gang LIU
  • Tetrahydropyranyl benzamide derivatives
    Patent number: 10196385
    Abstract: The present invention provides compounds of the Formula below wherein R, R1-R3 are as described herein; methods of treating patients for diabetes using the compounds, and processes for preparing the compounds.
    Type: Grant
    Filed: February 19, 2016
    Date of Patent: February 5, 2019
    Assignee: Eli Lilly and Company
    Inventors: Zhi Long Hu, Lian Zhu Liu, Tianwei Ma, Haizhen Zhang, Jingye Zhou
  • Tetrahydropyranyl Benzamide Derivatives
    Publication number: 20180194755
    Abstract: The present invention provides compounds of the Formula below wherein R, R1-R3 are as described herein; methods of treating patients for diabetes using the compounds, and processes for preparing the compounds
    Type: Application
    Filed: February 19, 2016
    Publication date: July 12, 2018
    Inventors: Zhi Long Hu, Lian Zhu Liu, Tianwei Ma, Haizhen Zhang, Jingye Zhou
  • GPR142 agonist compounds
    Patent number: 9861613
    Abstract: The present invention provides compounds of the Formula (Ia) wherein R is selected from the group consisting of CH3, CH(CH3)2, CH2CN, CH2CHF2, CH2CF3, (A), (B), (C), (D), (E), (F), CH2CH2OCH3, and CH2C(O)OCH(CH3)2; R1 is selected from the group consisting of CF3, OCF3, and Cl; R2 is selected from the group consisting of H and F; or a pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: January 22, 2015
    Date of Patent: January 9, 2018
    Assignee: Eli Lilly and Company
    Inventors: Zhi Long Hu, Lian Zhu Liu, Tianwei Ma, Mi Emily Zeng, Jingye Zhou
  • GPR142 Agonist Compounds
    Publication number: 20170165234
    Abstract: The present invention provides compounds of the Formula (Ia) wherein R is selected from the group consisting of CH3, CH(CH3)2, CH2CN, CH2CHF2, CH2CF3, (A), (B), (C), (D), (E), (F), CH2CH2OCH3, and CH2C(O)OCH(CH3)2; R1 is selected from the group consisting of CF3, OCF3, and Cl; R2 is selected from the group consisting of H and F; or a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: January 22, 2015
    Publication date: June 15, 2017
    Inventors: Zhi Long Hu, Lian Zhu Liu, Tianwei Ma, Mi Emily Zeng, Jingye Zhou