Abstract: A system for improving a cardiac ablation procedure includes a recommendation unit configured to provide an initial recommendation for at least one proposed ablation line for an ablation procedure on an anatomy of a patient. The system displays the at least one proposed ablation line on an anatomical map of the anatomy. The recommendation unit comprises a first and a second trained machine-learning model. Both the first and second trained machine-learning models have the same structure.

Abstract: Apparatus and methods are described for use of a sensor for monitoring a subject generate a sensor signal in response to the monitoring. Also disclosed is a computer processor to analyze the signal, and in response thereto, identify a correspondence between positions of the subject and occurrences of health events of the subject, and generate an output on the output device, in response to the identified correspondence. Other applications are also described.

Abstract: An ablation procedure guidance method is provided herein. The ablation procedure guidance method is implemented by a generation engine executing on a processor. The ablation procedure guidance method includes receiving inputs including images and conduction velocity vector estimations and generating a digital twin of an anatomical structure utilizing the images and the conduction velocity vector estimations. The ablation procedure guidance method also includes presenting, via a user interface of the generation engine, the digital twin to provide precision ablation guidance of the anatomical structure and provide electrophysiology information of the anatomical structure.

Abstract: A method includes receiving a data set including medical information of respective patients, respective types of a clinical procedure performed on the patients, and respective survival rates of the patients. A survival tree graph is generated by maximizing a cost function of differences in the survival rates between the types of the clinical treatment procedure. A type of the clinical procedure is selected for a given patient, based on the survival tree graph.

Abstract: Apparatus and methods are described for monitoring a subject. A sensor monitors the subject and generates a sensor signal in response thereto and a plurality of filters are used to filter the sensor signal using respective filter parameters. A computer processor receives the sensor signal, filters the signal with each of two or more of the filters, and in response to a quality of each of the filtered signals, selects one of the plurality of filters to filter the sensor signal. Subsequently, the computer processor detects that the subject has undergone motion, by analyzing the sensor signal, and in response thereto, filters the signal with each of two or more of the filters, and in response to a quality of each of the filtered signals, selects one of the plurality of filters to filter the sensor signal. Other applications are also described.

Abstract: A method and apparatus of aiding a physician in locating an area to perform an ablation on patients with atrial fibrillation (AFIB) includes receiving data at a machine, from at least one device, the data including information relating to a desired location for performing an ablation, generating, by the machine, an optimal location for performing the ablation based upon the data and inputs, and providing an optimal set of ablation parameters for performing the ablation at the location output by the model, or at a location specified by the physician.

Abstract: A method is provided. The method includes receiving input intracardiac signals from a monitoring and processing apparatus. Each of the input intracardiac signals includes artifacts. The method includes encoding, by an autoencoder, the input intracardiac signals utilizing an intracardiac dataset to produce a latent representation. The method also includes decoding, by an autoencoder, the latent representation to produce output intracardiac signals. The output intracardiac signals include the input intracardiac signals reconstructed without the signal artifacts.

Abstract: A system and method include a memory storing processor executable code for a denoised autoencoder, and one or more processors coupled to the memory to execute the processor executable code to receive raw signal data comprising signal noise, encode, by the denoised autoencoder, the raw signal data by performing a denoising autoencoder operation to produce a latent representation, and decode, by the denoised autoencoder, the latent representation to produce clean signal data reconstructed without the signal noise. A first filter is applied to a signal to emphasize activity within the signal and to produce a first modified signal, a rectifier and a second filter are applied to the first modified signal to smooth areas of the first modified signal with clinical importance and to produce a second modified signal, and high frequency energy zones of the second modified signal are automatically detected using an energy threshold to produce a weights vector.

Abstract: Apparatus and methods are described for use with a seat (82) of a vehicle, including a sensor unit (80) configured to be placed underneath the seat and configured to detect motion of a subject who is sitting on the seat during motion of the vehicle. The sensor unit includes a housing (90, 100), a first motion sensor (96, 106) disposed within the housing such as to generate a first sensor signal that is indicative of the motion of the vehicle, and a second motion sensor (98, 108) disposed within the housing, such as to generate a second sensor signal that is indicative of the motion of the subject and the motion of the vehicle. A computer processor at least partially distinguishes between motion of the subject and motion of the vehicle by analyzing the first and second sensor signals. Other applications are also described.

Abstract: A system includes an interface and a processor. The interface is configured to receive data that characterizes an initial ablation operation applied to a region of a heart of a patient. The processor is configured to automatically specify, based on the received data, if found required, a complementary ablation operation to be applied to the region.

Abstract: A system includes an interface and a processor. The interface is configured to receive a plurality of electrophysiological (EP) measurements performed in a heart of a patient. The processor is configured to estimate a wall thickness at a specified location of the heart based on the EP measurements.

Abstract: Apparatus and methods are described for monitoring a female subject. A sensor is configured to monitor the subject without contacting the subject or clothes the subject is wearing, and without viewing the subject or clothes the subject is wearing, and to generate a sensor signal in response to the monitoring. A computer processor is configured to receive the sensor signal, and to analyze the sensor signal. In response to the analyzing, the computer processor is configured to automatically identify a menstrual state of the subject, and to generate an output in response thereto. Other applications are also described.

Abstract: Apparatus and methods are described including apparatus for monitoring a female subject that includes a sensor, configured to monitor the subject without requiring compliance of the subject, and to generate a sensor signal in response to the monitoring. A computer processor is configured to receive the sensor signal, analyze the sensor signal, in response to the analyzing, identify whether the subject is in a pregnant state or a non-pregnant state, and generate an output in response thereto. Other applications are also described.

Abstract: A method including applying an agent to skin of a subject; and facilitating delivery of the agent into the skin by focusing ultrasound energy to a focal zone that is less than 0.2 mm in depth from a surface of the skin. Other applications are also described.

Abstract: Apparatus comprising an ultrasound ablation system, which comprises a reflection-facilitation element, configured to be placed at an extramyocardial site of a subject, and to provide an extramyocardial reflective region; and an ultrasound tool, which comprises at least one ultrasound transducer configured to be positioned within a heart chamber of the subject. The ultrasound transducer is configured to ablate myocardial tissue by applying ultrasound energy to the myocardial tissue such that at least a portion of the transmitted energy is reflected by the reflective region onto the myocardial tissue. Other embodiments are also described.

Abstract: Apparatus is provided for ablating cardiac tissue of a subject. The apparatus comprises an inflatable element, configured to be transthoracically placed within a pericardial region of the subject and a reflection-facilitation element, configured to deliver a fluid to the pericardial region, such that a portion of the fluid is disposed within the inflatable element, and another portion of the fluid is disposed outside of the inflatable element and inside the pericardial region. The apparatus additionally comprises at least one ultrasound transducer, configured to be transcatheterally placed in a heart chamber of the subject, and to apply ultrasound energy such that at least a portion of the applied energy is reflected by the fluid. Other embodiments are also described.

Abstract: Apparatus and methods are described for use with a seat (82) of a vehicle, including a sensor unit (80) configured to be placed underneath the seat and configured to detect motion of a subject who is sitting on the seat during motion of the vehicle. The sensor unit includes a housing (90, 100), a first motion sensor (96, 106) disposed within the housing such as to generate a first sensor signal that is indicative of the motion of the vehicle, and a second motion sensor (98, 108) disposed within the housing, such as to generate a second sensor signal that is indicative of the motion of the subject and the motion of the vehicle. A computer processor at least partially distinguishes between motion of the subject and motion of the vehicle by analyzing the first and second sensor signals. Other applications are also described.

Abstract: Cartridge apparatus (230) for use with a handle (220) is provided. The apparatus includes a housing (500) which: (a) includes a handle-coupling portion (235) shaped and sized to securely couple the housing to the handle and to facilitate separation of the housing from the handle, (b) shaped to define a skin-application portion (40) on an outer surface of the housing, and (c) includes at least one ultrasound element (60) in acoustic communication with the skin-application portion and configured to transmit ultrasound energy to the skin through the skin-application portion when the cartridge is attached to the handle. The cartridge apparatus also includes an inflatable element (250) inflated with a fluid, the fluid being in fluid communication with the skin-application portion. Other applications are also described.

Abstract: Apparatus is described for use with a burglar alarm that includes a detector configured to detect activity and to generate an activity-detection signal in response thereto. A sensor monitors a resting surface and generates a signal in response thereto. A control unit identifies a correspondence between (a) the activity-detection signal, and (b) the signal that is generated by the sensor. The control unit inhibits the burglar alarm from being triggered, in response to the correspondence. Other applications are also described.