Patents by Inventor Libero A. Gardella

Libero A. Gardella has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Gelatin-encapsulated digoxin solutions and method of preparing the same
    Patent number: 4002718
    Abstract: Digoxin solutions are disclosed which are compatible with gelatin and which are of relatively high concentration, thereby permitting encapsulation of therapeutic amounts of digoxin in soft gelatin capsules of moderate size. The digoxin is first micronized and then dissolved in a vehicle consisting predominately of polyethylene glycol having a molecular weight no greater than about one thousand and having a melting temperature no greater than about 35.degree. C., to provide a digoxin concentration of at least one-half milligram per milliliter and preferably one milligram per milliliter. Solutions composed of various solvent blends are disclosed, including solutions which are highly viscous (semi-solid) at room temperature.
    Type: Grant
    Filed: October 16, 1974
    Date of Patent: January 11, 1977
    Assignee: Arnar-Stone Laboratories, Inc.
    Inventors: Libero A. Gardella, Helen Kesler