Patents by Inventor Libo Xu

Libo Xu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Aryloxyacetic acids for diabetes and lipid disorders
    Patent number: 6569879
    Abstract: A class of aryloxyacetic acids comprises compounds that are potent agonists of PPAR alpha and/or gamma, and are therefore useful in the treatment, control or prevention of non-insulin dependent diabetes mellitus (NIDDM), hyperglycemia, dyslipidemia, hyperlipidemia, hypercholesterolemia, hypertriglyceridemia, atherosclerosis, obesity, vascular restenosis, inflammation, and other PPAR alpha and/or gamma mediated diseases, disorders and conditions.
    Type: Grant
    Filed: August 17, 2001
    Date of Patent: May 27, 2003
    Assignee: Merck & Co., Inc.
    Inventors: Kun Liu, Libo Xu, A. Brian Jones
  • Aryloxyacetic acids for diabetes and lipid disorders
    Publication number: 20020173663
    Abstract: A class of aryloxyacetic acids comprises compounds that are potent agonists of PPAR alpha and/or gamma, and are therefore useful in the treatment, control or prevention of non-insulin dependent diabetes mellitus (NIDDM), hyperglycemia, dyslipidemia, hyperlipidemia, hypercholesterolemia, hypertriglyceridemia, atherosclerosis, obesity, vascular restenosis, inflammation, and other PPAR alpha and/or gamma mediated diseases, disorders and conditions.
    Type: Application
    Filed: August 17, 2001
    Publication date: November 21, 2002
    Inventors: Kun Liu, Libo Xu, A. Brian Jones
  • Universal linker for combinatorial synthesis
    Patent number: 6093799
    Abstract: A substrate for solid phase synthesis of the formula: ##STR1## is disclosed. Also disclosed are processes for preparing the substrate and intermediates useful therein. Among the novel intermediates are compounds of the formula: ##STR2## wherein t is 0 or 1; n is 3-20; R is OH, an activated ester or the residue of a solid support having a plurality of amino functionalities; A is --O-- or --NH-- and Q is hydrogen or a protecting group for an amine or alcohol.
    Type: Grant
    Filed: October 20, 1999
    Date of Patent: July 25, 2000
    Assignee: Pharmacopeia, Inc.
    Inventors: Ge Li, Sian Louise Griffiths, Edward McDonald, Libo Xu
  • Universal linker for combinatorial synthesis
    Patent number: 6008321
    Abstract: A substrate for solid phase synthesis of the formula: ##STR1## is disclosed. Also disclosed are processes for preparing the substrate and intermediates useful therein. Among the novel intermediates are compounds of the formula: ##STR2## wherein t is 0 or 1; n is 3-20; R is OH, an activated ester or the residue of a solid support having a plurality of amino functionalities; A is --O-- or --NH-- and Q is hydrogen or a protecting group for an amine or alcohol.
    Type: Grant
    Filed: March 16, 1998
    Date of Patent: December 28, 1999
    Assignee: Pharmacopeia, Inc.
    Inventors: Ge Li, Sian Louise Griffiths, Edward McDonald, Libo Xu