Patents by Inventor Librada Maria Canedo

Librada Maria Canedo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ANTICANCER COMPOUNDS
    Publication number: 20210317490
    Abstract: Anticancer compounds of general formula I wherein R1 to R4 take various meanings, for use in the treatment of cancer. A novel Labrenzia sp. strain named PHM005 with Accession Deposit Number CECT-9225, a method of producing compounds of the invention and analogues thereof by using the PHM005 strain and the Lab gene cluster codifying the biosynthesis of pederin-like and onnamide-like compounds are also provided.
    Type: Application
    Filed: March 16, 2018
    Publication date: October 14, 2021
    Inventors: Librada María CAÑEDO HERNÁNDEZ, Fernando DE LA CALLE VERDÚ, María Pilar RODRÍGUEZ RAMOS, María del Carmen SCHLEISSNER SÁNCHEZ, Paz ZÚÑIGA GIRÓN
  • TRICYCLIC PYRROLE COMPOUNDS, THEIR PREPARATION AND USE IN MEDICAMENTS
    Publication number: 20160152566
    Abstract: The invention refers to compounds of general formula (I) wherein the variables take the various meanings, pharmaceutical compositions containing them and their use in medicine. The compounds have shown to be useful in therapy as angiogenesis inhibitors. The compounds are isolated from the fermentation broth of a fungal strain Paraconiothyrium sp., or are derivatives thereof.
    Type: Application
    Filed: July 8, 2014
    Publication date: June 2, 2016
    Inventors: Antonio FERNÁNDEZ MEDARDE, Librada Maria CANEDO HERNÁNDEZ, María De Los Ángeles VINUESA-NAVARRO, José María SÁNCHEZ LÓPEZ, Belinda CALVO PELAZ, Marta MARTÍNEZ INSUA, Ana RODRÍGUEZ-QUESADA, Melissa CARCÍA-CABALLERO, Miguel-Ángel MEDINA-TORRES
  • Use of collismycin and derivatives thereof as oxidative stress inhibitors
    Patent number: 8067441
    Abstract: The present invention relates to the use of Collismycin and derivatives thereof as inhibitors of oxidative stress in cells and their use for the preparation of medicaments for the treatment of oxidative stress-induced diseases or conditions, especially neurodegenerative diseases, such as Alzheimer's Disease and Parkinson's Disease.
    Type: Grant
    Filed: July 28, 2006
    Date of Patent: November 29, 2011
    Assignees: Neuropharma, S.A., Instituto Biomar, S.A.
    Inventors: Ana Martinez Gil, Paola Usan Egea, Miguel Medina Padilla, Esther Garcia Palomero, Julia Perez Baz, Rosa Isabel Fernandez Chimeno, Antonio Medarde Fernandez, Librada Maria Canedo Hernandez, Francisco Romero Millan, Ana Castro Morera, Mercedes Alonso Cascon, Jorge Sanchez Quesada
  • TERPENES WITH ANTIFUNGAL ACTIVITY AGAINST MALASSEZIA YEASTS
    Publication number: 20100184853
    Abstract: The present invention relates to the use of some terpenes, for example chlovalicin, ovalicin or fumagillin, as antifungal against Malassezia species and to their use in the manufacture of medicaments for the treatment of human skin diseases caused by these Malassezia species, such as pityriasis versicolor, seborrheic dermatitis, dandruff, atopic dermatitis, psoriasis, confluent and reticulated papillomatosis, onychomycosis, and transient acantholytic dermatosis.
    Type: Application
    Filed: June 13, 2008
    Publication date: July 22, 2010
    Applicant: INSTITUTO BIOMAR, S.A.
    Inventors: Librada Maria Canedo Hernandez, Maria De Los Angeles Vinuesa-Navarro, Antonio Fernandez-Medarde
  • Use of Collismycin and Derivatives Thereof as Oxidative Stress Inhibitors
    Publication number: 20080275088
    Abstract: The present invention relates to the use of Collismycin and derivatives thereof as inhibitors of oxidative stress in cells and their use for the preparation of medicaments for the treatment and/or prevention of oxidative stress-induced diseases or conditions, especially neurodegenerative diseases, such as Alzheimer's Disease and Parkinson's Disease.
    Type: Application
    Filed: July 28, 2006
    Publication date: November 6, 2008
    Applicants: NEUROPHARMA, S.A., INSTITUTO BIOMAR, S.A.
    Inventors: Ana Martinez Gil, Paola Usan Egea, Miguel Medina Padilla, Esther Garcia Palomero, Julia Perez Baz, Rosa Isabel Fernandez Chimeno, Antonio Medarde Fernandez, Librada Maria Canedo Hernandez, Francisco Romero Millan, Ana Castro Morera, Mercedes Alonso Cascon, Jorge Sanchez Quesada
  • Cytotoxic depsipeptides
    Patent number: 7446094
    Abstract: Compounds of general formula (I) wherein R1, R2, R3 are as defined and R4 groups are each independently selected from NR2, O and S; are of use in treatment of cancers.
    Type: Grant
    Filed: June 23, 2004
    Date of Patent: November 4, 2008
    Assignee: Instituto Biomar S.A.
    Inventors: Paco Romero, Leyre Malet, Librada Maria Cañedo, Carmen Cuevas, José Fernando Reyes
  • Indolocarbazole alkaloids from a marine actinomycete
    Patent number: 6852715
    Abstract: The invention provides compounds of formula (1) wherein R1 is a hydrogen atom, an alkyl group having 1 to 6 carbon atoms or an alkoxy group having 1 to 6 carbon atoms; and R2 is a hydrogen atom, an alkyl group having 1 to 6 carbon atoms or an alkoxy group having 1 to 6 carbon atoms; and pharmaceutically acceptable salts thereof. The invention also relates to a process for obtaining the compounds, compositions containing them and their therapeutic use. The compounds display excellent activity against mammalian cancer cell lines.
    Type: Grant
    Filed: June 28, 2000
    Date of Patent: February 8, 2005
    Assignee: Instituto Biomar S.A.
    Inventors: Dolores Garcia Gravalos, Julia Perez, Librada Maria Cañedo, Francisco Romero, Fernando Espliego
  • Polycylic xanthones and their use
    Patent number: 6812245
    Abstract: A novel class of antitumour compounds has been recognised based on the isolation from a new marine microbe, strain PO13-046, belonging to the genus Actinomadura sp.), of a compound designated IB-00208. The class of the formulae (I) or (II) where R1 can be hydrogen, acyl, alkyl, alkenyl, aryl, benzyl, alkali metal, and/or sugar, and R2 and R3 can be hydrogen, alkyl, or together R2 and R3 form an unsaturated bond. Such compounds demonstrate an interesting activity several cancel cell lines and against Gram-positive bacteria.
    Type: Grant
    Filed: June 9, 2003
    Date of Patent: November 2, 2004
    Assignee: Instituto Biomar S.A.
    Inventors: Librada Maria Cañedo, Dolores Garcia Gravalos, Francisco Romero, Fernando Espliego, Julia Perez-Baz
  • Use of citreamicins
    Publication number: 20030236291
    Abstract: Citreamicins possess useful antitumor activity. Typically they are of formula, wherein R1 is selected from the group consisting of COCH2CH(CH3)2, COCH3 or H when R2 is CH3, or wherein R1 is COCH2CH(CH3)2, and R2 is H.
    Type: Application
    Filed: July 25, 2003
    Publication date: December 25, 2003
    Inventors: Dolores Garcia Gravalos, Jose Luis Fernandez Puentes, Librada Maria Canedo Fernandez, Julia Perez-Baz, Francisco Romero-Millan, Fernando Espliego-Vazquez
  • Macrolides with antitumor activity
    Patent number: 6395711
    Abstract: The compound referred to herein as IB-962 12, having structure (I) can be obtained by cultivating the strain of Micromonospora sp. ES25-008, available under the accession number CECT-3333, and can be hydrolyzed to give IB-96212B having structure (II). The sugar substituent which is L-rhodinose, can its elf be derivatized or the sugar can be replaced, in either case, giving further derivatives of IB-96212 having a group other than L-rhodinose at the position of the sugar.
    Type: Grant
    Filed: April 17, 2000
    Date of Patent: May 28, 2002
    Assignee: Instituto Biomar S.A.
    Inventors: Rosa Isabel Fernandez-Chimeno, Francisco Romero, Jose Luis Fernandez-Puentes, Julia Perez-Baz, Librada Maria Canedo, Fernando Espliego
  • Immunosuppressive sesbanimide compositions and methods of treatment using same
    Publication number: 20010039041
    Abstract: The active component of the pharmaceutical composition of the present invention is a compound which has been isolated from the controlled aerobic fermentation of a marine microorganism, Agrobacterium sp. PH-103.
    Type: Application
    Filed: January 8, 2001
    Publication date: November 8, 2001
    Applicant: Pharma Mar, S.a.
    Inventors: Glynn T. Faircloth, Francisco Romero Millan, Librada Maria Canedo Fernandez, Cristina Accbal Sarabia