Abstract: The disclosure belongs to the technical field related to additive manufacturing model preprocessing, and discloses a field-based additive manufacturing digital model feature identification and extraction method and device, the method can convert the digital model represented by the facet into a signed distance field and introduce a simulated physical field of the forming/service simulation, the feature distance field after the frequency domain analysis filtering, and the geometric feature field obtained by the multi-precision convolution unit analysis according to the requirement of feature to be identified, then, multiple fields are combined to realize feature classification determination and labeling of features, and finally feature extraction is completed based on field data and isosurface and isoline reconstruction algorithms.

Abstract: Disclosed are free-form curved surface slicing method and device based on implicit model, includes following: (1) Using mesh model of layered curved surface to intersect with implicit model of a part to be manufactured to obtain contour lines; (2) Comparing rules for intersecting contour lines and meshes within mesh, mesh coordinates are substituted into implicit model, obtaining a position of an intersection point of contour lines in corresponding mesh; (3) Using interpolation method to calculate intersection coordinates of contour lines and mesh boundary, specifying storing sequence of interpolation points, storing intersection points of discrete line segments in mesh; (4) Merging unordered point sets obtained to establish topological relationship between point sets and discrete line segments, each line segment corresponds to two endpoints, each endpoint corresponds to two line segments, based on above, all points traversed will be connected into complete and ordered profile, that is sliced profile.

Abstract: Methods of sequencing a protein using a novel digestion-on-emitter technology are provided.

Abstract: Methods of sequencing a protein using a novel digestion-on-emitter technology are provided.

Abstract: A roller bearing includes an outer ring, an inner ring, at least one row of rollers arranged between the outer ring and the inner ring, and at least one optical fiber cable mounted to the outer ring or the inner ring, the optical fiber cable including at least one Bragg grating. The optical fiber cable is configured such that a signal in the optical fiber cable is usable to determine a preload or load on the roller bearing.

Abstract: A selective laser sintering (SLS) device. The SLS device includes a laser forming unit, a support platform and a driving mechanism. The support platform is configured to support a plurality of raw materials for additive manufacturing of an object including a plurality of sections. The laser forming unit is disposed on the support platform and is configured to lay powders on a surface of each section of the object and sinter the powders. The driving mechanism is disposed under the laser forming unit and includes a vertical driving mechanism and a horizontal driving mechanism. The vertical driving mechanism is connected to the laser forming unit and configured to lift the laser forming unit layer by layer. The horizontal driving mechanism is configured to drive the laser forming unit to move in a horizontal direction with respect to the support platform.

Abstract: The invention belongs to the field of filament additive manufacturing, and discloses a polymer multi-material high-flexibility laser additive manufacturing system and a method thereof. The system comprises a first robot arm, a second robot arm, a positioner, a rotational extrusion nozzle in which a plurality of extrusion modules are disposed and a laser, each extrusion module is used for extruding one kind of filament, and the rotational extrusion nozzle is connected with the first robot which drives the rotational extrusion nozzle to move according to a preset trajectory; the laser is connected with the second robot, and is used for emitting a laser to fuse the filament extruded from the rotational extrusion nozzle, and through the cooperative motion of the first robot and the second robot, the extrusion and fusion of the filament are performed synchronously; the positioner serves as a forming mesa, and the rotation of the positioner cooperates with the motions of the two robots.

Abstract: A selective laser sintering (SLS) device. The SLS device includes a laser forming unit, a support platform and a driving mechanism. The support platform is configured to support a plurality of raw materials for additive manufacturing of an object including a plurality of sections. The laser forming unit is disposed on the support platform and is configured to lay powders on a surface of each section of the object and sinter the powders. The driving mechanism is disposed under the laser forming unit and includes a vertical driving mechanism and a horizontal driving mechanism. The vertical driving mechanism is connected to the laser forming unit and configured to lift the laser forming unit layer by layer. The horizontal driving mechanism is configured to drive the laser forming unit to move in a horizontal direction with respect to the support platform.

Abstract: A roller bearing includes an outer ring, an inner ring, at least one row of rollers arranged between the outer ring and the inner ring, and at least one optical fiber cable mounted to the outer ring or the inner ring, the optical fiber cable including at least one Bragg grating. The optical fiber cable is configured such that a signal in the optical fiber cable is usable to determine a preload or load on the roller bearing.

Abstract: Methods of sequencing a protein using a novel digestion-on-emitter technology are provided.

Abstract: The invention belongs to the field of filament additive manufacturing, and discloses a polymer multi-material high-flexibility laser additive manufacturing system and a method thereof. The system comprises a first robot arm, a second robot arm, a positioner, a rotational extrusion nozzle in which a plurality of extrusion modules are disposed and a laser, each extrusion module is used for extruding one kind of filament, and the rotational extrusion nozzle is connected with the first robot which drives the rotational extrusion nozzle to move according to a preset trajectory; the laser is connected with the second robot, and is used for emitting a laser to fuse the filament extruded from the rotational extrusion nozzle, and through the cooperative motion of the first robot and the second robot, the extrusion and fusion of the filament are performed synchronously; the positioner serves as a forming mesa, and the rotation of the positioner cooperates with the motions of the two robots.

Abstract: The application discloses compositions, methods, systems, and apparatuses for rapid sequence analysis of proteins, including location of post-translational modifications and disulfide bonds. Limited digestion of fully denatured antibody occurs in seconds by flowing sample in 8M urea at constant pressure through a micro column reactor containing immobilized aspergillopepsin I, resulting in a product mixture containing 3-10 kDa peptides, which is then fractionated by capillary column chromatography and analyzed by both electron transfer dissociation (ETD) and collision activated dissociation mass spectrometry. This method provides 95% sequence coverage of a mAb and detects numerous post-translational modifications. For disulfide bond location, native mAb is subjected to longer digestion times. Release of disulfide containing peptides from accessible regions of the folded protein occurs with short digestion times.

Abstract: A depolarizer, including: a photoalignment layer deposited on the substrate; and a birefringent layer deposited on the photoalignment layer; wherein the photoalignment layer includes a plurality of segments, each segment with a different fast axis orientation and a different pretilt angle, such that each segment of the birefringent layer over the corresponding segment of the photoalignment layer has a different fast axis angle and a different birefringent value.

Abstract: The application discloses, compositions, methods, systems, and apparatuses for rapid sequence analysis of proteins, including location of post-translational modifications and disulfide bonds, is described. Limited digestion of fully denatured antibody occurs in seconds by flowing sample in 8 M urea at constant pressure through a micro column reactor containing immobilized aspergillopepsin I, resulting in a product mixture containing 3-10 kDa peptides, which is then fractionated by capillary column chromatography and analyzed by both electron transfer dissociation (ETD) and collision activated dissociation mass spectrometry. This method provides 95% sequence coverage of a mAb and detects numerous post-translational modifications. For disulfide bond location, native mAb is subjected to longer digestion times. Release of disulfide containing peptides from accessible regions of the folded protein occurs with short digestion times.

Abstract: A depolarizer, including: a photoalignment layer deposited on the substrate; and a birefringent layer deposited on the photoalignment layer; wherein the photoalignment layer includes a plurality of segments, each segment with a different fast axis orientation and a different pretilt angle, such that each segment of the birefringent layer over the corresponding segment of the photoalignment layer has a different fast axis angle and a different birefringent value.