Patents by Inventor Lichen XIANG

Lichen XIANG has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Rapid nucleic acids separation and sample preparation via hollow-centered silica microsphere
    Patent number: 11746372
    Abstract: Disclosed herein are method for separating, amplifying, or detecting a nucleic acid from a sample may comprise contacting a sample lysate with a plurality of buoyant, inorganic, nucleic-acid-capture microspheres. The nucleic-acid-capture microspheres may comprise unicellular hollow microspheres having a diameter between 5 and 300 ?m and/or a true particle density between 0.05 and 0.60 grams/cm3. The microspheres may comprise hollow soda-lime-borosilicate microspheres. In some embodiments, the microspheres comprises hollow soda-lime-borosilicate microspheres surrounded by an amorphous silica shell. Also disclosed are kits for performing the methods.
    Type: Grant
    Filed: December 3, 2018
    Date of Patent: September 5, 2023
    Assignees: GoDx, Inc., The United States of America, as Represented by the Secretary, Dep. of Health and Human Services
    Inventors: Chang Hee Kim, Lichen Xiang, Wendy A. Henderson, Xiao Jiang
  • RAPID NUCLEIC ACIDS SEPARATION AND SAMPLE PREPARATION VIA HOLLOW-CENTERED SILICA MICROSPHERE
    Publication number: 20210180108
    Abstract: Disclosed herein are method for separating, amplifying, or detecting a nucleic acid from a sample may comprise contacting a sample lysate with a plurality of buoyant, inorganic, nucleic-acid-capture microspheres. The nucleic-acid-capture microspheres may comprise unicellular hollow microspheres having a diameter between 5 and 300 ?m and/or a true particle density between 0.05 and 0.60 grams/cm3. The microspheres may comprise hollow soda-lime-borosilicate microspheres. In some embodiments, the microspheres comprises hollow soda-lime-borosilicate microspheres surrounded by an amorphous silica shell. Also disclosed are kits for performing the methods.
    Type: Application
    Filed: December 3, 2018
    Publication date: June 17, 2021
    Applicants: GoDx, Inc, The United States of America, as Represented by the Secretary, Department of Health and Human Servic
    Inventors: Chang Hee KIM, Lichen XIANG, Wendy A. HENDERSON, Xiao JIANG